This readme.txt file was generated on 2020-MM-DD ------------------- GENERAL INFORMATION ------------------- 1. Title of Dataset: 200925 OSA - Open Access Data Dog breeds and body conformations with predisposition to osteosarcoma in the UK, a restropective case-control analysis - Supporting Data 2. Author Information: Principal Investigator Contact Information Name: Grace L. Edmunds Institution: Bristol Veterinary School, Address: Langford House, Langford, Bristol, BS40 5DU, UK Email: ge8793@bristol.ac.uk Co-investigator Contact Information Name: Matthew J. Smalley Institution: European Cancer Stem Cell Research Institute Address: Hadyn Ellis Building, Maindy Road, CF24 4HQ Email: SmalleyMJ@Cardiff.ac.uk Name: Sam Beck Institution: Address: Horner Court, 637 Gloucester Road, Horfield, Bristol, BS7 0BJ, UK Email: sam.beck@synlab.co.uk Name: Rachel J. Errington Institution: School of Medicine Address: Cardiff University, Heath Park, Cardiff, United Kingdom CF14 4ER Email: ErringtonRJ@cardiff.ac.uk Name: Sara Gould Institution: Langford Veterinary Services Address: Langford House Langford, BS40 5DU Email: sg16003@bristol.ac.uk Name: Helen Winter Institution: Bristol Cancer Institute Address: Bristol, BS2 8ED Email: helen.winter@uhbw.nhs.uk Name: Dave C. Brodbelt Institution: Pathobiology and Population Sciences, The Royal Veterinary College Address: Hawkshead Lane, North Mymms, Hatfield, Herts AL9 7TA, UK Name: Dan G. O'Neill, Institution: Pathobiology and Population Sciences, The Royal Veterinary College Address: Hawkshead Lane, North Mymms, Hatfield, Herts AL9 7TA, UK Email: doneill@rvc.ac.uk 3. Dates of data collection: VPG: January 2008 and January 2020 VetCompass: 2016 4. Geographic location of data collection: UK 5. Information about funding sources that supported the collection of the data: N/A -------------------------- SHARING/ACCESS INFORMATION -------------------------- 1. Licenses/restrictions placed on the data: These VetCompass™ data are made available to assist interested readers of the original papers to delve deeper into some of the results provided, and to enhance academic rigour and reproducibility by enabling external scrutiny and also to provide learning resources for students. As an academic research programme, VetCompass is also very keen to share open access data that may be useful for undergraduate and postgraduate students to explore and analyse as a learning resource. It should be noted, though, that the open access data generally represent just a subsection of the complete original study data. VetCompass contributors are able to share these sections of data openly in accordance with current ethical considerations and data protection regulations. Fields with sensitive, confidential or identifying information from the original full datasets have been redacted. Datasets may also hold curtailed lists of study animals. Safe inferences derived from the full, unredacted datasets are summarised in the accompanying peer-reviewed publication. VetCompass emphasises that full understanding of the provenance and context of any dataset is an essential component for safe interpretation. Such understanding by the original researchers will have been critical for the validity of the peer-reviewed publication. Further inference without this core contextual understanding and without access to the full dataset should be regarded as incomplete and provisional at best. These Open Access data are provided: • Purely for validation and learning exercise purposes • With no ethical permissions for use in further formal research • With no warranty or assurances for completeness or veracity • With no background information on the context beyond that which is described in the originating publication. • With no additional support offered by the original researchers or authors • With no responsibility of any kind accepted by the Royal Veterinary College or VetCompass on any matters arising from the access, sharing, analysis or outcomes of usage of these data in any way. 2. Links to publications that cite or use the data: 3. Links to other publicly accessible locations of the data: N/A 4. Links/relationships to ancillary data sets: N/A 5. Was data derived from another source? VPG: Cases included all dogs with osteosarcoma in a database of biopsies submitted to VPG Histology (Bristol, UK) between January 2008 and January 2020 inclusive VetCompass: Yes. These data were shared from UK veteirnary clinics participating in VetCompass. 6. Recommended citation for the data: --------------------- DATA & FILE OVERVIEW --------------------- 1. File List A. Filename: 200925 OSA - Open Access Data Short description: Spreadsheet of some data that are allowed to be shared and that support the associated publication 2. Relationship between files: N/A 3. Additional related data collected that was not included in the current data package: Data that hold identifying information. 4. Are there multiple versions of the dataset No -------------------------- METHODOLOGICAL INFORMATION -------------------------- 1. Description of methods used for collection/generation of data: As described in the accompanying publication. 2. Methods for processing the data: A section of the raw study data have been exported as a CSV file. The dataset has been fully anonymised by removing any client and animal details that might enable the client to be identified. 3. Instrument- or software-specific information needed to interpret the data: CSV is a common data exchange format that is widely supported by consumer, business, and scientific applications including Excel (Microsoft) and Numbers (Apple). 4. Standards and calibration information, if appropriate: N/A 5. Environmental/experimental conditions: N/A 6. Describe any quality-assurance procedures performed on the data: A section of the raw study data have been provided. 7. People involved with sample collection, processing, analysis and/or submission: The study authors as listed in the accompanying paper. ----------------------------------------- DATA-SPECIFIC INFORMATION FOR: Final_Data_PLOS.csv ----------------------------------------- 1. Number of variables: 6 2. Number of rows: 906.967 rows 3. Variable List A. Name: Open Access - Patient ID Description: ID number assigned to dog(disguised/anonymised) B. Name: Source breed Description: Patient's breed C. Name: Sex Description: True if male D. Name: Neutered Description: True if neutered E. Name: BirthDate Description: Date of birth F. Name: OSA case or noncase Description: OSA cases or noncases 4. Missing data codes: Unknown: Status not known Empty cell: Data not available 5. Specialized formats of other abbreviations used: N/A