@article { , title = {Odontoameloblastoma with extensive chondroid matrix deposition in a guinea pig}, abstract = {Odontoameloblastomas (previously incorporated within ameloblastic odontomas) are matrix-producing odontogenic mixed tumors and are closely related in histologic appearance to the 2 other types of matrix-producing odontogenic mixed tumors: odontomas and ameloblastic fibro-odontomas. The presence or absence of intralesional, induced non-neoplastic tissue must be accounted for in the diagnosis. Herein we describe a naturally occurring odontoameloblastoma with extensive chondroid cementum deposition in a guinea pig (Cavia porcellus). Microscopically, the mass featured palisading neoplastic odontogenic epithelium closely apposed to ribbons and rings of a pink dental matrix (dentinoid), alongside extensive sheets and aggregates of chondroid cementum. The final diagnosis was an odontoameloblastoma given the abundance of odontogenic epithelium in association with dentinoid but a paucity of pulp ectomesenchyme. Chondroid cementum is an expected anatomical feature of cavies, and its presence within the odontoameloblastoma was interpreted as a response of the ectomesenchyme of the dental follicle to the described neoplasm. Our case illustrates the inductive capabilities of odontoameloblastomas while highlighting species-specific anatomy that has resulted in a histologic appearance unique to cavies and provides imaging and histologic data to aid diagnosis of these challenging lesions.}, doi = {10.1177/1040638718794784}, issn = {1040-6387}, journal = {JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION}, publicationstatus = {Published}, publisher = {SAGE Publications}, url = {https://rvc-repository.worktribe.com/output/1386194}, keyword = {ePrints migration}, year = {2018}, author = {Wong, H E and Hedley, J and Stapleton, N and Murphy, B and Priestnall, S L} }