Pathobiology and Population Sciences

Risk factors associated with Rift Valley fever epidemics in South Africa in 2008–11
Journal Article
Metras, R., Jewell, C., Porphyre, T., Thompson, P. N., Pfeiffer, D. U., Collins, L. M., & White, R. G. (in press). Risk factors associated with Rift Valley fever epidemics in South Africa in 2008–11. https://doi.org/10.1038/srep09492

Genomic signatures of human and animal disease in the zoonotic pathogen Streptococcus suis
Journal Article
Weinert, L. A., Chaudhuri, R. R., Wang, J., Peters, S. E., Corander, J., Jombart, T., Baig, A., Howell, K. J., Vehkala, M., Valimaki, N., Harris, D., Tran Thi Bich, C., Nguyen Van Vinh, C., Campbell, J., Schultsz, C., Parkhill, J., Bentley, S. D., Langford, P. R., Rycroft, A. N., Wren, B. W., …BRaDP1T Consortium. (in press). Genomic signatures of human and animal disease in the zoonotic pathogen Streptococcus suis. Nature Communications, 6, https://doi.org/10.1038/ncomms7740

Streptococcus suis causes disease in pigs worldwide and is increasingly implicated in zoonotic disease in East and South-East Asia. To understand the genetic basis of disease in S. suis, we study the genomes of 375 isolates with detailed clinical phe... Read More about Genomic signatures of human and animal disease in the zoonotic pathogen Streptococcus suis.

a-Synuclein-Induced Synapse Damage in Cultured Neurons Is Mediated by Cholesterol-Sensitive Activation of Cytoplasmic Phospholipase A2
Journal Article
Bate, C., & Williams, A. (in press). a-Synuclein-Induced Synapse Damage in Cultured Neurons Is Mediated by Cholesterol-Sensitive Activation of Cytoplasmic Phospholipase A2. Biomolecules, 5(1), 178-93. https://doi.org/10.3390/biom5010178

The accumulation of aggregated forms of the α-synuclein (αSN) is associated with the pathogenesis of Parkinson’s disease (PD) and Dementia with Lewy Bodies. The loss of synapses is an important event in the pathogenesis of these diseases. Here we sho... Read More about a-Synuclein-Induced Synapse Damage in Cultured Neurons Is Mediated by Cholesterol-Sensitive Activation of Cytoplasmic Phospholipase A2.

Farmers taking responsibility for herd health development—stable schools in research and advisory activities as a tool for dairy health and welfare planning in Europe
Journal Article
Ivemeyer, S., Bell, N. J., Brinkmann, J., Cimer, K., Gratzer, E., Leeb, C., March, S., Mejdell, C., Roderick, S., Smolders, G., Walkenhorst, M., Winckler, C., & Vaarst, M. (in press). Farmers taking responsibility for herd health development—stable schools in research and advisory activities as a tool for dairy health and welfare planning in Europe. Organic Agriculture, 5(2), 135-141. https://doi.org/10.1007/s13165-015-0101-y

Evaluation of treatments for claw horn lesions in dairy cows in a randomized controlled trial
Journal Article
Thomas, H. J., Miguel-Pacheco, G. G., Bollard, N. J., Archer, S. C., Bell, N. J., Mason, C., Maxwell, O. J. R., Remnant, J. G., Sleeman, P., Whay, H. R., & Huxley, J. N. (in press). Evaluation of treatments for claw horn lesions in dairy cows in a randomized controlled trial. Journal of Dairy Science, 98, 1-10. https://doi.org/10.3168/jds.2014-8982

Livestock trade networks for guiding animal health surveillance
Journal Article
Hardstaff, J. L., Haesler, B., & Rushton, J. (in press). Livestock trade networks for guiding animal health surveillance. BMC Veterinary Research, 11(1), 82. https://doi.org/10.1186/s12917-015-0354-4

Effects of Ex-Vivo and In-Vivo Treatment with Probiotics on the Inflammasome in Dogs with Chronic Enteropathy
Journal Article
Schmitz, S., Werling, D., & Allenspach, K. (in press). Effects of Ex-Vivo and In-Vivo Treatment with Probiotics on the Inflammasome in Dogs with Chronic Enteropathy. PLoS ONE, 10(3), e0120779. https://doi.org/10.1371/journal.pone.0120779

Inflammasomes coordinate the maturation of IL-1β and IL-18 in response to danger signals. They are vital for maintenance of intestinal homeostasis and have been linked to chronic intestinal inflammation in humans. Probiotics have been advocated as tr... Read More about Effects of Ex-Vivo and In-Vivo Treatment with Probiotics on the Inflammasome in Dogs with Chronic Enteropathy.

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