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Predicted Impact of COVID-19 on Neglected Tropical Disease Programs and the Opportunity for Innovation

Toor, J; Adams, E R; Aliee, M; Amoah, B; Anderson, R M; Ayabina, D; Bailey, R; Basáñez, M G; Blok, D J; Blumberg, S; Borlase, A; Rivera, R C; Castaño, M S; Chitnis, N; Coffeng, L E; Crump, R E; Das, A; Davis, C N; Davis, E L; Deiner, M S; Diggle, P J; Fronterre, C; Giardina, F; Giorgi, E; Graham, M; Hamley, J I D; Huang, C I; Kura, K; Lietman, T M; Lucas, T C D; Malizia, V; Medley, G F; Meeyai, A; Michael, E; Porco, T C; Prada, J M; Rock, K S; Le Rutte, E A; Smith, M E; Spencer, S E F; Stolk, W A; Touloupou, P; Vasconcelos, A; Vegvari, C; de Vlas, S J; Walker, M; Hollingsworth, T D


J Toor

E R Adams

M Aliee

B Amoah

R M Anderson

D Ayabina

R Bailey

M G Basáñez

D J Blok

S Blumberg

A Borlase

R C Rivera

M S Castaño

N Chitnis

L E Coffeng

R E Crump

A Das

C N Davis

E L Davis

M S Deiner

P J Diggle

C Fronterre

F Giardina

E Giorgi

M Graham

J I D Hamley

C I Huang

K Kura

T M Lietman

T C D Lucas

V Malizia

G F Medley

A Meeyai

E Michael

T C Porco

J M Prada

K S Rock

E A Le Rutte

M E Smith

S E F Spencer

W A Stolk

P Touloupou

A Vasconcelos

C Vegvari

S J de Vlas

M Walker

T D Hollingsworth


Abstract Due to the COVID-19 pandemic, many key neglected tropical disease (NTD) activities have been postponed. This hindrance comes at a time when the NTDs are progressing towards their ambitious goals for 2030. Mathematical modelling on several NTDs, namely gambiense sleeping sickness, lymphatic filariasis, onchocerciasis, schistosomiasis, soil-transmitted helminthiases (STH), trachoma, and visceral leishmaniasis, shows that the impact of this disruption will vary across the diseases. Programs face a risk of resurgence, which will be fastest in high-transmission areas. Furthermore, of the mass drug administration diseases, schistosomiasis, STH, and trachoma are likely to encounter faster resurgence. The case-finding diseases (gambiense sleeping sickness and visceral leishmaniasis) are likely to have fewer cases being detected but may face an increasing underlying rate of new infections. However, once programs are able to resume, there are ways to mitigate the impact and accelerate progress towards the 2030 goals.


Toor, J., Adams, E. R., Aliee, M., Amoah, B., Anderson, R. M., Ayabina, D., …Hollingsworth, T. D. (2020). Predicted Impact of COVID-19 on Neglected Tropical Disease Programs and the Opportunity for Innovation. Clinical Infectious Diseases,

Journal Article Type Article
Acceptance Date Jul 10, 2020
Publication Date Sep 28, 2020
Deposit Date Oct 7, 2020
Publicly Available Date Oct 7, 2020
Journal Clinical Infectious Diseases
Print ISSN 1058-4838
Publisher Oxford University Press
Peer Reviewed Peer Reviewed
Keywords Microbiology (medical), Infectious Diseases
Public URL


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