A novel mammalian glucokinase exhibiting exclusive inorganic polyphosphate dependence in the cell nucleus

Ali, A; Wathes, D C; Swali, A; Burns, H; Burns, S

Abstract

We report the discovery of a polyphosphate-dependent enzyme system in mammalian cells with kinetics similar to established ATP-dependent glucokinase, also known to have a nuclear location. The kinetics suggest possible regulatory or redox protective roles.

Citation

Ali, A., Wathes, D. C., Swali, A., Burns, H., & Burns, S. (2017). A novel mammalian glucokinase exhibiting exclusive inorganic polyphosphate dependence in the cell nucleus. https://doi.org/10.1016/j.bbrep.2017.09.004

• Journal Article Type: Article
• Acceptance Date: Sep 15, 2017
• Publication Date: Sep 20, 2017
• Deposit Date: Oct 17, 2017
• Publicly Available Date: Oct 17, 2017
• Journal: Biochemistry and Biophysics Reports
• Peer Reviewed: Peer Reviewed
• Volume: 12
• Pages: 151-157
• DOI: https://doi.org/10.1016/j.bbrep.2017.09.004
• Public URL: https://rvc-repository.worktribe.com/output/1390507