Quantitative pharmacodynamic characterization of resistance vs. heteroresistance of colistin in E. coli using a semi-mechanistic modelling of killing curves
(2022)
Journal Article
Mead, A., Toutain, P.-L., Richez, P., & Pelligand, L. (2022). Quantitative pharmacodynamic characterization of resistance vs. heteroresistance of colistin in E. coli using a semi-mechanistic modelling of killing curves. Antimicrobial Agents and Chemotherapy, https://doi.org/10.1128/aac.00793-22
Heteroresistance correspond to the presence in a bacterial isolate of an initial small subpopulation of bacteria characterized by a significant reduction in their sensitivity to a given antibiotic. Mechanisms of heteroresistance vs. resistance are po... Read More about Quantitative pharmacodynamic characterization of resistance vs. heteroresistance of colistin in E. coli using a semi-mechanistic modelling of killing curves.