All Outputs (5)

Biofabrication of the osteochondral unit and its applications: Current and future directions for 3D bioprinting (2022)
Journal Article
Santos-Beato, P., Midha, S., Pitsillides, A., Miller, A., Torii, R., & Kalaskar, D. (2022). Biofabrication of the osteochondral unit and its applications: Current and future directions for 3D bioprinting. Journal of Tissue Engineering, 13, https://doi.org/10.1177/20417314221133480

Multiple prevalent diseases, such as osteoarthritis (OA), for which there is no cure or full understanding, affect the osteochondral unit; a complex interface tissue whose architecture, mechanical nature and physiological characteristics are still ye... Read More about Biofabrication of the osteochondral unit and its applications: Current and future directions for 3D bioprinting.

Increased PHOSPHO1 expression mediates cortical bone mineral density in renal osteodystrophy (2022)
Journal Article
Hsu, S., Stephen, L., Dillon, S., Milne, E., Javaheri, B., Pitsillides, A., …Farquharson, C. (2022). Increased PHOSPHO1 expression mediates cortical bone mineral density in renal osteodystrophy. Journal of Endocrinology, 254(3), 167-181. https://doi.org/10.1530/JOE-22-0097

Patients with advanced chronic kidney disease (CKD) often present with skeletal abnormalities, a condition known as renal osteodystrophy (ROD). While tissue non-specific alkaline phosphatase (TNAP) and PHOSPHO1 are critical for bone mineralization, t... Read More about Increased PHOSPHO1 expression mediates cortical bone mineral density in renal osteodystrophy.

MCTR3 reprograms arthritic monocytes to upregulate Arginase-1 and exert pro-resolving and tissue-protective functions in experimental arthritis (2022)
Journal Article
Pistorius, K., Ly, L., Souza, P., Gomez, E., Koenis, D., Rodriguez, A., …Dalli, J. (2022). MCTR3 reprograms arthritic monocytes to upregulate Arginase-1 and exert pro-resolving and tissue-protective functions in experimental arthritis. EBioMedicine, 79, https://doi.org/10.1016/j.ebiom.2022.103974

TYROSINE KINASE INHIBITOR ALW-II-41-27 ATTENUATES OSTEOPHYTOSIS AND SYNOVITIS IN MICE (2022)
Journal Article
Blanco, M., Kops, N., Fahy, N., Bastiaansen-Jenniskens, Y., Chambers, M., Pitsillides, A., …van Osch, G. (2022). TYROSINE KINASE INHIBITOR ALW-II-41-27 ATTENUATES OSTEOPHYTOSIS AND SYNOVITIS IN MICE. Osteoarthritis and Cartilage, 30, S432-S433. https://doi.org/10.1016/j.joca.2022.02.586

Moving beyond the limits of detection: the past, the present, and the future of diagnostic imaging in canine osteoarthritis (2022)
Journal Article
Jones, G., Pitsillidies, A., & Meeson, R. (2022). Moving beyond the limits of detection: the past, the present, and the future of diagnostic imaging in canine osteoarthritis. Frontiers in Veterinary Science, https://doi.org/10.3389/fvets.2022.789898

Osteoarthritis (OA) is the most common orthopaedic condition in dogs, characterised as chronic, painful end-point of a synovial joint with limited therapeutic options other than palliative pain control or surgical salvage. Since the 1970s, radiograph... Read More about Moving beyond the limits of detection: the past, the present, and the future of diagnostic imaging in canine osteoarthritis.