Comparison of cellular assays for TLR activation and development of a species-specific reporter cell line for cattle

Tombacz, K; Mwangi, D; Werling, D; Gibson, A J

doi:10.1177/1753425917695445

All Outputs (3)

Polymorphisms in the selectin gene cluster are associated with fertility and survival time in a population of Holstein Friesian cows (2017)
Journal Article
Chen, X., Zhang, S., Cheng, Z. R., Cooke, J. S., Werling, D., Wathes, D. C., & Pollott, G. E. (2017). Polymorphisms in the selectin gene cluster are associated with fertility and survival time in a population of Holstein Friesian cows. PLoS ONE, 12(4), https://doi.org/10.1371/journal.pone.0175555

Selectins are adhesion molecules, which mediate attachment between leucocytes and endothelium. They aid extravasation of leucocytes from blood into inflamed tissue during the mammary gland’s response to infection. Selectins are also involved in attac... Read More about Polymorphisms in the selectin gene cluster are associated with fertility and survival time in a population of Holstein Friesian cows.

Subset-specific expression of Toll-like receptors by bovine afferent lymph dendritic cells (2017)
Journal Article
Werling, D., Hope, J., Siddiqui, N., Widdison, S., Russell, C., Sopp, C., & Coffey, T. J. (2017). Subset-specific expression of Toll-like receptors by bovine afferent lymph dendritic cells. Frontiers in Veterinary Science, 4(44), https://doi.org/10.3389/fvets.2017.00044

Comparison of cellular assays for TLR activation and development of a species-specific reporter cell line for cattle (2017)
Journal Article
Tombacz, K., Mwangi, D., Werling, D., & Gibson, A. J. (2017). Comparison of cellular assays for TLR activation and development of a species-specific reporter cell line for cattle. Innate Immunity, 23(4), 329-335. https://doi.org/10.1177/1753425917695445

PRRs are sentinels of the innate immune system, with TLRs being the most important. Assays for TLR ligand interactions have been used to gain insights into their function and signaling pathways. As significant differences exist between species with r... Read More about Comparison of cellular assays for TLR activation and development of a species-specific reporter cell line for cattle.