Insulin, but not adiponectin, is detectable in equine saliva using an automated, commercial assay
(2023)
Journal Article
Menzies-Gow, N., Elliott, J., & Barnabe, M. (2023). Insulin, but not adiponectin, is detectable in equine saliva using an automated, commercial assay. Equine Veterinary Journal, https://doi.org/10.1111/evj.14019
All Outputs (12)
Short-term induced hyperinsulinaemia and dexamethasone challenge do not affect circulating total adiponectin concentrations in insulin-sensitive ponies (2023)
Journal Article
Barnabé, M., Elliott, J., Harris, P., & Menzies-Gow, N. (2023). Short-term induced hyperinsulinaemia and dexamethasone challenge do not affect circulating total adiponectin concentrations in insulin-sensitive ponies. Equine Veterinary Journal, https://doi.org/10.1111/evj.14012BackgroundHypoadiponectinaemia is a risk factor for endocrinopathic laminitis, but the directionality and nature of its association with insulin dysregulation is unclear.ObjectivesTo investigate the effects of short-term induced hyperinsulinaemia and... Read More about Short-term induced hyperinsulinaemia and dexamethasone challenge do not affect circulating total adiponectin concentrations in insulin-sensitive ponies.
Factors associated with insulin responses to oral sugars in a mixed-breed cohort of ponies (2023)
Journal Article
Knowles, E., Harris, P., Elliott, J., Chang, Y., & Menzies-Gow, N. (2023). Factors associated with insulin responses to oral sugars in a mixed-breed cohort of ponies. Equine Veterinary Journal, https://doi.org/10.1111/evj.13983Background: Serum insulin concentration at 60 min (InsulinT60) during an oral sugar test (OST) indicates future laminitis risk and insulin dysregulation (ID). Associations between InsulinT60 and physical and owner-reported variables may help clinicia... Read More about Factors associated with insulin responses to oral sugars in a mixed-breed cohort of ponies.
Therapeutics of managing reduced red cell mass associated with chronic kidney disease – is there a case for earlier intervention? (2023)
Journal Article
Elliott, J. (in press). Therapeutics of managing reduced red cell mass associated with chronic kidney disease – is there a case for earlier intervention?. Journal of Veterinary Pharmacology and Therapeutics, https://doi.org/10.1111/jvp.13127Reduced red cell mass is a poor prognostic indicator in chronic kidney disease (CKD) patients. Whilst overt anaemia impacts on the quality of life of patients with CKD, lowered red cell mass may also compromise oxygen delivery to proximal tubular ce... Read More about Therapeutics of managing reduced red cell mass associated with chronic kidney disease – is there a case for earlier intervention?.
Short Communication: Identification of equine corticotropin-like intermediate lobe peptide (CLIP) binding to an adrenocortipcotrophic hormone (ACTH) assay capture antibody (2023)
Journal Article
Knowles, E., Hyde, C., Harris, P., Elliott, J., & Menzies-Gow, N. (2023). Short Communication: Identification of equine corticotropin-like intermediate lobe peptide (CLIP) binding to an adrenocortipcotrophic hormone (ACTH) assay capture antibody. Domestic Animal Endocrinology, https://doi.org/10.1016/j.domaniend.2023.106785A chemiluminescent immunoassay is commonly employed to measure adrenocorticotrophic hormone (ACTH) concentrations to assist pituitary pars intermedia dysfunction diagnosis. In a previous study, seasonally dependent assay cross-reactivity to endogenou... Read More about Short Communication: Identification of equine corticotropin-like intermediate lobe peptide (CLIP) binding to an adrenocortipcotrophic hormone (ACTH) assay capture antibody.
Consequences of adiponectin deficiency – can they be related to the pathophysiology of laminitis? (2023)
Journal Article
Elliott, J., & Bailey, S. (in press). Consequences of adiponectin deficiency – can they be related to the pathophysiology of laminitis?. Equine Veterinary Journal, https://doi.org/10.1111/evj.13932No abstract available
Risk factors for upper urinary tract uroliths and ureteral obstruction in cats under referral veterinary care in the United Kingdom (2023)
Journal Article
Geddes, R. F., Davison, L. J., Elliott, J., Syme, H. M., & O'Neill, D. G. (2023). Risk factors for upper urinary tract uroliths and ureteral obstruction in cats under referral veterinary care in the United Kingdom. Journal of Veterinary Internal Medicine, 37(2), 567-577. https://doi.org/10.1111/jvim.16659Background
Cats presenting with upper urinary tract uroliths (UUTUs) and ureteral obstruction (“obstructive UUTU”) are typically younger than cats with idiopathic CKD that often have incidental nephroliths.
Hypothesis
Cats with upper urinary tra... Read More about Risk factors for upper urinary tract uroliths and ureteral obstruction in cats under referral veterinary care in the United Kingdom.
A review of cellular and molecular mechanisms in endocrinopathic, sepsis-related and supporting limb equine laminitis (2023)
Journal Article
Elliott, J. (2023). A review of cellular and molecular mechanisms in endocrinopathic, sepsis-related and supporting limb equine laminitis. Equine Veterinary Journal, https://doi.org/10.1111/evj.13933Equine laminitis has both fascinated and frustrated veterinary researchers and clinicians for many years. The recognition that many ponies suffering from pasture associated laminitis have an insulin dysregulated phenotype (endocrinopathic laminitis,... Read More about A review of cellular and molecular mechanisms in endocrinopathic, sepsis-related and supporting limb equine laminitis.
A review of cellular and molecular mechanisms in endocrinopathic, sepsis-related and supporting limb equine laminitis (2023)
Journal Article
Elliott, J., & Bailey, S. (in press). A review of cellular and molecular mechanisms in endocrinopathic, sepsis-related and supporting limb equine laminitis. Equine Veterinary Journal, https://doi.org/10.1111/evj.13933Equine laminitis has both fascinated and frustrated veterinary researchers and clinicians for many years. The recognition that many ponies suffering from pasture associated laminitis have an insulin dysregulated phenotype (endocrinopathic laminitis,... Read More about A review of cellular and molecular mechanisms in endocrinopathic, sepsis-related and supporting limb equine laminitis.
Assessment of peritubular capillary rarefaction in kidneys of cats with chronic kidney disease (2023)
Journal Article
Paschall, R., Quimby, J., Cianciolo, R., McLeland, S., Lunn, K., & Elliott, J. (2023). Assessment of peritubular capillary rarefaction in kidneys of cats with chronic kidney disease. Journal of Veterinary Internal Medicine, 37(2), 556-566. https://doi.org/10.1111/jvim.16656BackgroundHypoxia is a key driver of fibrosis and is associated with capillary rarefaction in humans. ObjectivesCharacterize capillary rarefaction in cats with chronic kidney disease (CKD). AnimalsArchival kidney tissue from 58 cats with CKD, 20 unaf... Read More about Assessment of peritubular capillary rarefaction in kidneys of cats with chronic kidney disease.
Relationships between total adiponectin concentrations and obesity in native-breed ponies in England (2023)
Journal Article
Barnabe, M., Elliott, J., Harris, P., & Menzies-Gow, N. (in press). Relationships between total adiponectin concentrations and obesity in native-breed ponies in England. Equine Veterinary Journal, https://doi.org/10.1111/evj.14013Background: Equine metabolic syndrome is a collection of risk factors associated with an increased risk of endocrinopathic laminitis. All affected animals display insulin dysregulation and some may show adiponectin dysregulation and/or excessive adip... Read More about Relationships between total adiponectin concentrations and obesity in native-breed ponies in England.
Predictors of laminitis development in a cohort of nonlaminitic ponies (2023)
Journal Article
Knowles, E., Elliott, J., Harris, P., Chang, Y., & Menzies-Gow, N. (2023). Predictors of laminitis development in a cohort of nonlaminitic ponies. Equine Veterinary Journal, https://doi.org/10.1111/evj.13572Background Quantifying risk factors for laminitis development requires improvement. Objectives To identify the most useful physical examination, metabolic and management factors to predict laminitis development in client-owned, nonlaminitic ponies. S... Read More about Predictors of laminitis development in a cohort of nonlaminitic ponies.