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Global transcriptomic profiles of circulating leucocytes in early lactation cows with clinical or subclinical mastitis (2021)
Journal Article
Cheng, Z., Buggiotti, L., Salavati, M., Marchitelli, C., Palma-Vera, S., Wylie, A., …GplusE Consortium. (in press). Global transcriptomic profiles of circulating leucocytes in early lactation cows with clinical or subclinical mastitis. Molecular Biology Reports,

Bovine mastitis is an inflammatory disease of the mammary gland, which is classified as subclinical or clinical. Circulating neutrophils are recruited to the udder to help combat infection. We compared the transcriptomic profiles in circulating leuko... Read More about Global transcriptomic profiles of circulating leucocytes in early lactation cows with clinical or subclinical mastitis.

Mining the Unmapped Reads in Bovine RNA-Seq Data Reveals the Prevalence of Bovine Herpes Virus-6 in European Dairy Cows and the Associated Changes in Their Phenotype and Leucocyte Transcriptome (2020)
Journal Article
Buggiotti, L., Cheng, Z., Wathes, C., & GplusE Consortium, G. (in press). Mining the Unmapped Reads in Bovine RNA-Seq Data Reveals the Prevalence of Bovine Herpes Virus-6 in European Dairy Cows and the Associated Changes in Their Phenotype and Leucocyte Transcriptome. Viruses, 12(12), 1451. https://doi.org/10.3390/v12121451

Microbial RNA is detectable in host samples by aligning unmapped reads from RNA sequencing against taxon reference sequences, generating a score proportional to the microbial load. An RNA-Seq data analysis showed that 83.5% of leukocyte samples from... Read More about Mining the Unmapped Reads in Bovine RNA-Seq Data Reveals the Prevalence of Bovine Herpes Virus-6 in European Dairy Cows and the Associated Changes in Their Phenotype and Leucocyte Transcriptome.

Relationships between metabolic profiles and gene expression in liver and leukocytes of dairy cows in early lactation (2020)
Dataset
Cheng, Z., Wathes, D. C., Buggiotti, L., Salavati, M., Takeda, H., Tang, L., …Crowe, M. A. Relationships between metabolic profiles and gene expression in liver and leukocytes of dairy cows in early lactation. [Dataset]. https://doi.org/10.34840/q4vd-m506

Homeorhetic mechanisms assist dairy cows to transition from pregnancy to lactation. Less successful cows develop severe negative energy balance (NEB), placing them at risk of metabolic and infectious disease and reduced fertility. We have previously... Read More about Relationships between metabolic profiles and gene expression in liver and leukocytes of dairy cows in early lactation.