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All Outputs (4)

Optimisation and validation of immunohistochemical axonal markers for morphological and functional characterisation of equine peripheral nerves (2021)
Journal Article
Almuhanna, A., Cahalan, S., Lane, A., Goodwin, D., Perkins, J., & Piercy, R. (2021). Optimisation and validation of immunohistochemical axonal markers for morphological and functional characterisation of equine peripheral nerves. Equine Veterinary Journal, 53(6), 1188-1198. https://doi.org/10.1111/evj.13403

Background: Horses are affected by various peripheral nerve disorders but defining their aetiology and pathophysiology is hampered by limited understanding of associated morphological and pathological changes and involvement of specific axonal types.... Read More about Optimisation and validation of immunohistochemical axonal markers for morphological and functional characterisation of equine peripheral nerves.

Musculoskeletal magnetic resonance imaging in the DE50-MD dog model of Duchenne muscular dystrophy (2021)
Journal Article
Hornby, N., Drees, R., Harron, R., Chang, R., Wells, D., & Piercy, R. (2021). Musculoskeletal magnetic resonance imaging in the DE50-MD dog model of Duchenne muscular dystrophy. Neuromuscular Disorders, 31(8), 736-751. https://doi.org/10.1016/j.nmd.2021.05.010

The DE50-MD canine model of Duchenne muscular dystrophy (DMD) has a dystrophin gene splice site mutation causing deletion of exon 50, an out-of-frame transcript and absence of dystrophin expression in striated muscles. We hypothesized that the muscul... Read More about Musculoskeletal magnetic resonance imaging in the DE50-MD dog model of Duchenne muscular dystrophy.

A highly prevalent SINE mutation in the myostatin (MSTN) gene promoter is associated with low circulating myostatin concentration in Thoroughbred racehorses (2021)
Journal Article
O'Hara, V., Cowan, A., Riddell, D., Massey, C., Martin, J., & Piercy, R. (2021). A highly prevalent SINE mutation in the myostatin (MSTN) gene promoter is associated with low circulating myostatin concentration in Thoroughbred racehorses. Scientific Reports, 11(1), https://doi.org/10.1038/s41598-021-86783-1

Horse racing is a popular and financially important industry worldwide and researchers and horse owners are interested in genetic and training influences that maximise athletic performance. An association has been found between the presence of a shor... Read More about A highly prevalent SINE mutation in the myostatin (MSTN) gene promoter is associated with low circulating myostatin concentration in Thoroughbred racehorses.

Hypoglycin A absorption in sheep without concurrent clinical or biochemical evidence of disease (2021)
Journal Article
Gonzalez-Medina, S., Bevin, W., Alzola-Domingo, R., Chang, Y., & Piercy, R. (2021). Hypoglycin A absorption in sheep without concurrent clinical or biochemical evidence of disease. Journal of Veterinary Internal Medicine, 35(2), 1170-1176. https://doi.org/10.1111/jvim.16077

Background Hypoglycin A (HGA) intoxication after ingestion of Acer spp. tree material has never been confirmed in domesticated ruminants despite their similar grazing habitats. Objectives To investigate whether sheep have low HGA bioavailability caus... Read More about Hypoglycin A absorption in sheep without concurrent clinical or biochemical evidence of disease.