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Molecular characterisation and functional interrogation of a local natriuretic peptide system in rodent pituitaries, alpha T3-1 and L beta T2 gonadotroph cells
Journal Article
Thompson, I. R., Chand, A. N., Jonas, K. C., Burrin, J. M., Steinhelper, M. E., Wheeler-Jones, C. P. D., …Fowkes, R. C. Molecular characterisation and functional interrogation of a local natriuretic peptide system in rodent pituitaries, alpha T3-1 and L beta T2 gonadotroph cells. Journal of Endocrinology, 203(2), 215-229. https://doi.org/10.1677/joe-09-0189

11 beta-hydroxysteroid dehydrogenase enzymes in the testis and male reproductive tract of the boar (Sus scrofa domestica) indicate local roles for glucocorticoids in male reproductive physiology
Journal Article
Sharp, V., Thurston, L. M., Fowkes, R. C., & Michael, A. E. 11 beta-hydroxysteroid dehydrogenase enzymes in the testis and male reproductive tract of the boar (Sus scrofa domestica) indicate local roles for glucocorticoids in male reproductive physiology. Reproduction, 134(3), 473-482. https://doi.org/10.1530/REP-07-0126

Absence of pituitary adenylate cyclase-activating polypeptide-stimulated transcription of the human glycoprotein alpha-subunit gene in L beta T2 gonadotrophs reveals disrupted cAMP-mediated gene transcription
Journal Article
Fowkes, R. C., Sidhu, K. K., Sosabowski, J., King, P., & Burrin, J. M. Absence of pituitary adenylate cyclase-activating polypeptide-stimulated transcription of the human glycoprotein alpha-subunit gene in L beta T2 gonadotrophs reveals disrupted cAMP-mediated gene transcription. Journal of Molecular Endocrinology, 31(2), 263-278. https://doi.org/10.1677/jme.0.0310263

Regulation of human glycoprotein hormone α-subunit (αGSU) transcription in LβT2 gonadotropes by protein kinase C (PKC) and extracellular signal-regulated kinase 1/2 (ERK1/2)
Journal Article
Fowkes, R. C., King, P., & Burrin, J. M. Regulation of human glycoprotein hormone α-subunit (αGSU) transcription in LβT2 gonadotropes by protein kinase C (PKC) and extracellular signal-regulated kinase 1/2 (ERK1/2). Biology of Reproduction, 67(3), 725-734. https://doi.org/10.1095/biolreprod67.3.725

Regulation and Function of C-Type Natriuretic Peptide (CNP) in Gonadotrope-Derived Cell Lines
Journal Article
Mirczuk, S. M., Lessey, A. J., Catterick, A. R., Perrett, R. M., Scudder, C. J., Read, J. E., …Fowkes, R. C. (in press). Regulation and Function of C-Type Natriuretic Peptide (CNP) in Gonadotrope-Derived Cell Lines. Cells, 8(9), https://doi.org/10.3390/cells8091086

C-type natriuretic peptide (CNP) is the most conserved member of the mammalian natriuretic peptide family, and is implicated in the endocrine regulation of growth, metabolism and reproduction. CNP is expressed throughout the body, but is particularly... Read More about Regulation and Function of C-Type Natriuretic Peptide (CNP) in Gonadotrope-Derived Cell Lines.