Endochondral growth defect and deployment of transient chondrocyte behaviours underlie osteoarthritis onset in a natural murine model
(2016)
Journal Article
Staines, K. A., Madi, K., Mirczuk, S. M., Parker, S., Burleigh, A., Poulet, B., …Pitsillides, A. A. (2016). Endochondral growth defect and deployment of transient chondrocyte behaviours underlie osteoarthritis onset in a natural murine model. https://doi.org/10.1002/art.39508
All Outputs (65)
Studying Cat (Felis catus) Diabetes: Beware of the Acromegalic Imposter (2015)
Journal Article
Niessen, S. J. M., Forcada, Y., Mantis, P., Lamb, C. R., Harrington, N., Fowkes, R. C., …Church, D. B. (2015). Studying Cat (Felis catus) Diabetes: Beware of the Acromegalic Imposter. PLoS ONE, 10(5), e0127794. https://doi.org/10.1371/journal.pone.0127794
Homologous and heterologous desensitization of guanylyl cyclase-B signaling in GH3 somatolactotropes (2014)
Journal Article
Thompson, I. R., Mirczuk, S. M., Smith, L., Lessey, A. J., Simbi, B., Sunters, A., …Fowkes, R. C. (2014). Homologous and heterologous desensitization of guanylyl cyclase-B signaling in GH3 somatolactotropes. Cell and Tissue Research, 355(2), 425-36. https://doi.org/10.1007/s00441-013-1763-yThe guanylyl cyclases, GC-A and GC-B, are selective receptors for atrial and C-type natriuretic peptides (ANP and CNP, respectively). In the anterior pituitary, CNP and GC-B are major regulators of cGMP production in gonadotropes and yet mouse models... Read More about Homologous and heterologous desensitization of guanylyl cyclase-B signaling in GH3 somatolactotropes.
Pulsatile Hormonal Signaling to Extracellular Signal-Regulated Kinase: Exploring System Sensitivity to Gonadotropin-Releasing Hormone Pulse Frequency and Width (2014)
Journal Article
Perrett, R. M., Voliotis, M., Armstrong, S. P., Fowkes, R. C., Pope, G. R., Tsaneva-Atanasova, K., & McArdle, C. A. (2014). Pulsatile Hormonal Signaling to Extracellular Signal-Regulated Kinase: Exploring System Sensitivity to Gonadotropin-Releasing Hormone Pulse Frequency and Width. Journal of Biological Chemistry, 289(11), 7873-7883. https://doi.org/10.1074/jbc.M113.532473Gonadotropin-releasing hormone (GnRH) is secreted in brief pulses that stimulate synthesis and secretion of pituitary gonadotropin hormones and thereby mediate control of reproduction. It acts via G-protein-coupled receptors to stimulate effectors, i... Read More about Pulsatile Hormonal Signaling to Extracellular Signal-Regulated Kinase: Exploring System Sensitivity to Gonadotropin-Releasing Hormone Pulse Frequency and Width.
SUPPRESSION OF NUCLEAR FACTOR-kappaB ACTIVITY IN MACROPHAGES BY CHYLOMICRON REMNANTS: MODULATION BY THE FATTY ACID COMPOSITION OF THE PARTICLES
Journal Article
De Pascale, C., Graham, V. S., Fowkes, R. C., Wheeler-Jones, C. P. D., & Botham, K. M. SUPPRESSION OF NUCLEAR FACTOR-kappaB ACTIVITY IN MACROPHAGES BY CHYLOMICRON REMNANTS: MODULATION BY THE FATTY ACID COMPOSITION OF THE PARTICLES
Somatostatin Analogs Modulate AIP in Somatotroph Adenomas: The Role of the ZAC1 Pathway
Journal Article
Chahal, H. S., Trivellin, G., Leontiou, C. A., Alband, N., Fowkes, R. C., Tahir, A., …Korbonits, M. Somatostatin Analogs Modulate AIP in Somatotroph Adenomas: The Role of the ZAC1 Pathway. https://doi.org/10.1210/jc.2012-1111
Hypoxia-induced VEGF production 'RSUMEs' in pituitary adenomas
Journal Article
Fowkes, R. C., & Vlotides, G. Hypoxia-induced VEGF production 'RSUMEs' in pituitary adenomas. Endocrine-Related Cancer, 19(1), C1-C5. https://doi.org/10.1530/erc-11-0297
Expression of guanylyl cyclase-B (GC-B/NPR2) receptors in normal human fetal pituitaries and human pituitary adenomas implicates a regulatory role for C-type natriuretic peptide
Journal Article
Thompson, I. R., Chand, A. N., King, P. J., Ansorge, O., Karavitaki, N., Jones, C. A., …Fowkes, R. C. Expression of guanylyl cyclase-B (GC-B/NPR2) receptors in normal human fetal pituitaries and human pituitary adenomas implicates a regulatory role for C-type natriuretic peptide. Endocrine-Related Cancer, 19(4), 497-508. https://doi.org/10.1530/ERC-12-0129
Genetic Analysis of NR0B1 in Congenital Adrenal Hypoplasia Patients: Identification of a Rare Regulatory Variant Resulting in Congenital Adrenal Hypoplasia and Hypogonadal Hypogonadism without Testicular Carcinoma in situ
Journal Article
Walker, A. P., Fowkes, R. C., Saleh, F., Kim, S., Wilkinson, P., Cabrera-Sharp, V., …Bouloux, P. M. G. Genetic Analysis of NR0B1 in Congenital Adrenal Hypoplasia Patients: Identification of a Rare Regulatory Variant Resulting in Congenital Adrenal Hypoplasia and Hypogonadal Hypogonadism without Testicular Carcinoma in situ. Sexual Development, Online. https://doi.org/10.1159/000342295
LIKE A HOLE IN THE HEAD; DEVELOPMENT OF CRANIAL FORAMINA IN THE CHICK EMBRYO
Journal Article
Akbareian, S. E., Pitsillides, A. A., Fowkes, R. C., & McGonnell, I. M. LIKE A HOLE IN THE HEAD; DEVELOPMENT OF CRANIAL FORAMINA IN THE CHICK EMBRYO. Journal of Anatomy, 218(3), 351-351
THE ROLE OF THE C-TYPE NATRIURETIC PEPTIDE PATHWAY IN FORMATION OF CRANIAL FORAMINA IN THE CHICK EMBRYO
Journal Article
Akbareian, S. E., Thompson, I. R., Pitsillides, A. A., Fowkes, R. C., & McGonnell, I. M. THE ROLE OF THE C-TYPE NATRIURETIC PEPTIDE PATHWAY IN FORMATION OF CRANIAL FORAMINA IN THE CHICK EMBRYO. Endocrine Reviews, 31(3),
Pulsatile and Sustained Gonadotropin-releasing Hormone (GnRH) Receptor Signaling DOES THE ERK SIGNALING PATHWAY DECODE GnRH PULSE FREQUENCY?
Journal Article
Armstrong, S. P., Caunt, C. J., Fowkes, R. C., Tsaneva-Atanasova, K., & McArdle, C. A. Pulsatile and Sustained Gonadotropin-releasing Hormone (GnRH) Receptor Signaling DOES THE ERK SIGNALING PATHWAY DECODE GnRH PULSE FREQUENCY?. Journal of Biological Chemistry, 285(32), 24360-24371. https://doi.org/10.1074/jbc.M110.115964
A Maternal "Junk Food" Diet in Pregnancy and Lactation Promotes Nonalcoholic Fatty Liver Disease in Rat Offspring
Journal Article
Bayol, S. A. M., Simbi, B. H., Fowkes, R. C., & Stickland, N. C. A Maternal "Junk Food" Diet in Pregnancy and Lactation Promotes Nonalcoholic Fatty Liver Disease in Rat Offspring. Endocrinology, 151(4), 1451-1461. https://doi.org/10.1210/en.2009-1192
DEVELOPMENTAL AND FUNCTIONAL ROLE OF CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE II (CAMKII) ISOFORMS IN NORMAL HUMAN FETAL PITUITARY, L BETA T2 GONADOTROPES AND ZEBRAFISH NEUROENDOCRINETissues
Journal Article
Chand, A. C., Thompson, I. R., Akbareian, S. E., Toro, S., Anderson, R. A., McNeilly, A. S., …Fowkes, R. C. DEVELOPMENTAL AND FUNCTIONAL ROLE OF CALCIUM/CALMODULIN-DEPENDENT PROTEIN KINASE II (CAMKII) ISOFORMS IN NORMAL HUMAN FETAL PITUITARY, L BETA T2 GONADOTROPES AND ZEBRAFISH NEUROENDOCRINETissues. Endocrine Reviews, 31(3),
FISH AND CHICKS: C-TYPE NATRIURETIC PEPTIDE AND THE DEVELOPMENT OF THE PITUITARY GLAND IN GALLUS GALLUS AND DANIO RERIO
Journal Article
Chand, A. N., Akbareian, S. E., McGonnell, I. M., & Fowkes, R. C. FISH AND CHICKS: C-TYPE NATRIURETIC PEPTIDE AND THE DEVELOPMENT OF THE PITUITARY GLAND IN GALLUS GALLUS AND DANIO RERIO. Endocrine Reviews, 31(3),
L-Cysteine Stimulates Hydrogen Sulfide Synthesis in Myocardium Associated With Attenuation of Ischemia-Reperfusion Injury
Journal Article
Elsey, D. J., Fowkes, R. C., & Baxter, G. F. L-Cysteine Stimulates Hydrogen Sulfide Synthesis in Myocardium Associated With Attenuation of Ischemia-Reperfusion Injury. Journal of Cardiovascular Pharmacology and Therapeutics, 15(1), 53-59. https://doi.org/10.1177/1074248409357743
Regulation of cardiovascular cell function by hydrogen sulfide (H2S)
Journal Article
Elsey, D. J., Fowkes, R. C., & Baxter, G. F. Regulation of cardiovascular cell function by hydrogen sulfide (H2S). Cell Biochemistry and Function, 28(2), 95-106. https://doi.org/10.1002/cbf.1618
Nitric oxide/cGMP signalling mediates the cardioprotective action of adrenomedullin in reperfused myocardium
Journal Article
Hamid, S. A., Totzeck, M., Drexhage, C., Thompson, R. I., Fowkes, R. C., Rassaf, T., & Baxter, G. F. Nitric oxide/cGMP signalling mediates the cardioprotective action of adrenomedullin in reperfused myocardium. Basic Research in Cardiology, 105(2), 257-266. https://doi.org/10.1007/s00395-009-0058-7
DEVELOPMENT OF CRANIAL FORAMINA IN THE CHICK EMBRYO
Journal Article
Akbareian, S. E., Thompson, I. R., Pitsillides, A. A., Fowkes, R. C., & McGonnell, I. M. DEVELOPMENT OF CRANIAL FORAMINA IN THE CHICK EMBRYO. Developmental Biology, 331(2), 252. https://doi.org/10.1016/j.ydbio.2009.05.276
Pulsatile and Sustained Gonadotropin-releasing Hormone (GnRH) Receptor Signaling DOES THE Ca2+/NFAT SIGNALING PATHWAY DECODE GnRH PULSE FREQUENCY?
Journal Article
Armstrong, S. P., Caunt, C. J., Fowkes, R. C., Tsaneva-Atanasova, K., & McArdle, C. A. Pulsatile and Sustained Gonadotropin-releasing Hormone (GnRH) Receptor Signaling DOES THE Ca2+/NFAT SIGNALING PATHWAY DECODE GnRH PULSE FREQUENCY?. Journal of Biological Chemistry, 284(51), 35746-35757. https://doi.org/10.1074/jbc.M109.063917