Skip to main content

Research Repository

Advanced Search

All Outputs (358)

The Role Of Fstl3 In Spermatogenesis: A Transcriptome Analysis (2019)
Presentation / Conference Contribution
Ballesteros, R., Xia, D., O'Shaughnessy, P., & Mukherjee, A. The Role Of Fstl3 In Spermatogenesis: A Transcriptome Analysis

Spermatogenesis in mammals depends on the function of Sertoli cells (SC). The total number of SC present in the testes is determined in the pre-pubertal stages of development. Activin, a TGFβ family ligand, regulates SC proliferation in the early pos... Read More about The Role Of Fstl3 In Spermatogenesis: A Transcriptome Analysis.

FINITE ELEMENT ANALYSIS OF TISSUES WRAPPING AROUND THE KNEE JOINT OF OSTRICHES (STRUTHIO CAMELUS) (2015)
Presentation / Conference Contribution
Chadwick, K. P., Allen, V. R., & Hutchinson, J. R. FINITE ELEMENT ANALYSIS OF TISSUES WRAPPING AROUND THE KNEE JOINT OF OSTRICHES (STRUTHIO CAMELUS)

Mechanical stimulation is accepted to play some role in the development of sesamoid bones, however with great variability in occurrence, it is not yet clear how significant this role is and what specific loading environment fosters or hinders growth.... Read More about FINITE ELEMENT ANALYSIS OF TISSUES WRAPPING AROUND THE KNEE JOINT OF OSTRICHES (STRUTHIO CAMELUS).

DEVELOPING, TESTING AND OPTIMISING A MOUSE HINDLIMB MUSCULOSKELETAL MODEL (2015)
Presentation / Conference Contribution
Charles, J. P., Cappellari, O., Spence, A., Wells, D. J., & Hutchinson, J. R. DEVELOPING, TESTING AND OPTIMISING A MOUSE HINDLIMB MUSCULOSKELETAL MODEL

Stability during locomotion arises from many complex interactions which are not yet fully understood. Studies into how sensory feedback from muscle spindles contributes to this have used neuromechanical simulations, however their accuracy is limited... Read More about DEVELOPING, TESTING AND OPTIMISING A MOUSE HINDLIMB MUSCULOSKELETAL MODEL.

Considerations towards a roadmap for collection, handling and storage of blood extracellular vesicles
Presentation / Conference Contribution
Clayton, A., Boilard, E., Buzas, E. I., Cheng, L., Falcón-Perez, J. M., Gardiner, C., Gustafson, D., Gualerzi, A., Hendrix, A., Hoffman, A., Jones, J., Lässer, C., Lawson, C., Lenassi, M., Nazarenko, I., O’Driscoll, L., Pink, R., Siljander, P. R. M., Soekmadji, C., Wauben, M., …Nieuwland, R. Considerations towards a roadmap for collection, handling and storage of blood extracellular vesicles

There is an increasing interest in exploring clinically relevant information that is present in body fluids, and extracellular vesicles (EVs) are intrinsic components of body fluids (“liquid biopsies”). In this report, we will focus on blood. Blood c... Read More about Considerations towards a roadmap for collection, handling and storage of blood extracellular vesicles.

CHARACTERISING THE SPOTTY OSTEOMALACIA IN PHOSPHO1 KNOCKOUT MICE
Presentation / Conference Contribution
Boyde, A., Staines, K. A., Javaheri, B., Millan, J. L., Pitsillides, A. A., & Farquharson, C. CHARACTERISING THE SPOTTY OSTEOMALACIA IN PHOSPHO1 KNOCKOUT MICE. Presented at Joint Meeting of the Bone Research Society and Bone Matrix Research Society

GENERATION OF THREE-DIMENSIONAL HUMAN ARTIFICIAL SKELETAL MUSCLE TISSUE FROM IPS CELLS ENABLES COMPLEX DISEASE MODELLING FOR MUSCULAR DYSTROPHY
Presentation / Conference Contribution
Maffioletti, S. M., Sarcar, S., Henderson, A., Mannhardt, I., Pinton, L., Moyle, L. A., Steele-Stallard, H., Cappellari, O., Wells, K. E., Ragazzi, M., Wang, W., Zammit, P., Wells, D. J., Eschenhagen, T., & Tedesco, F. S. GENERATION OF THREE-DIMENSIONAL HUMAN ARTIFICIAL SKELETAL MUSCLE TISSUE FROM IPS CELLS ENABLES COMPLEX DISEASE MODELLING FOR MUSCULAR DYSTROPHY