Renal fibrosis in feline chronic kidney disease: known mediators and mechanisms of injury

Lawson, J S; Elliott, J; Wheeler-Jones, C P D; Syme, H M; Jepson, R E

doi:10.1016/j.tvjl.2014.10.009

World small animal veterinary association renal pathology initiative: classification of glomerular diseases in dogs (2015)
Journal Article
Cianciolo, R. E., Mohr, F. C., Aresu, L., Brown, C. A., James, C., Jansen, J. H., Spangler, W. L., van de Lugt, J., Kass, P., Brovida, C., Cowgill, L. D., Heiene, R., Polzin, D. J., Syme, H. M., Vaden, S. L., van Dongen, A. M., & Lees, G. E. (2015). World small animal veterinary association renal pathology initiative: classification of glomerular diseases in dogs. Veterinary Pathology, 53(1), 113-135. https://doi.org/10.1177/0300985815579996

Effect of Cyclooxygenase(COX)-1 and COX-2 inhibition on furosemide-induced renal responses and isoform immunolocalization in the healthy cat kidney (2015)
Journal Article
Pelligand, L., Suemanotham, N., King, J. N., Seewald, W., Syme, H. M., Smith, K. C., Lees, P., & Elliott, J. (2015). Effect of Cyclooxygenase(COX)-1 and COX-2 inhibition on furosemide-induced renal responses and isoform immunolocalization in the healthy cat kidney. BMC Veterinary Research, 11(296), https://doi.org/10.1186/s12917-015-0598-z

Autoantibodies against Cytochrome P450 Side-Chain Cleavage Enzyme in Dogs (Canis lupus familiaris) Affected with Hypoadrenocorticism (Addison's Disease) (2015)
Journal Article
Boag, A. M., Christie, M. R., McLaughlin, K. A., Syme, H. M., Graham, P., & Catchpole, B. (2015). Autoantibodies against Cytochrome P450 Side-Chain Cleavage Enzyme in Dogs (Canis lupus familiaris) Affected with Hypoadrenocorticism (Addison's Disease). PLoS ONE, 10(11), https://doi.org/10.1371/journal.pone.0143458

Neutrophil Gelatinase-Associated Lipocalin in Dogs With Sepsis Undergoing Emergency Laparotomy: A Prospective Case–Control Study (2015)
Journal Article
Cortellini, S., Pelligand, L., Syme, H. M., Chang, Y. M., & Adamantos, S. E. (2015). Neutrophil Gelatinase-Associated Lipocalin in Dogs With Sepsis Undergoing Emergency Laparotomy: A Prospective Case–Control Study. Journal of Veterinary Internal Medicine, 29(6), 1595-1602. https://doi.org/10.1111/jvim.13638

Relationship between plasma fibroblast growth factor-23 concentration and survival time in cats with chronic kidney disease (2015)
Journal Article
Geddes, R. F., Elliott, J., & Syme, H. M. (2015). Relationship between plasma fibroblast growth factor-23 concentration and survival time in cats with chronic kidney disease. Journal of Veterinary Internal Medicine, 29(6), 1494-1501. https://doi.org/10.1111/jvim.13625

Analysis of DLA-DQB1 and polymorphisms in CTLA4 in Cocker spaniels affected with immune-mediated haemolytic anaemia (2015)
Journal Article
Threlfall, A. J., Boag, A. M., Soutter, F., Glanemann, B., Syme, H. M., & Catchpole, B. (2015). Analysis of DLA-DQB1 and polymorphisms in CTLA4 in Cocker spaniels affected with immune-mediated haemolytic anaemia. Canine Genetics and Epidemiology, 2(8), https://doi.org/10.1186/s40575-015-0020-y

Feline Chronic Kidney Disease Is Associated with Upregulation of Transglutaminase 2: A Collagen Cross-Linking Enzyme (2015)
Journal Article
Sanchez-Lara, A. C., Elliott, J., Syme, H. M., Brown, C. A., & Haylor, J. L. (2015). Feline Chronic Kidney Disease Is Associated with Upregulation of Transglutaminase 2: A Collagen Cross-Linking Enzyme. Veterinary Pathology, 52(3), 513-523. https://doi.org/10.1177/0300985814542811

Chronic kidney disease is a major cause of morbidity and mortality in cats. Transglutaminase 2 (TG2) is a calcium-dependent enzyme proposed to mediate tubulointerstitial fibrosis in the kidney by cross-linking collagen fibrils. Postmortem kidney tiss... Read More about Feline Chronic Kidney Disease Is Associated with Upregulation of Transglutaminase 2: A Collagen Cross-Linking Enzyme.

Changes in systolic blood pressure over time in healthy cats and cats with chronic kidney disease (2015)
Journal Article
Bijsmans, E. S., Jepson, R. E., Chang, Y. M., Syme, H. M., & Elliott, J. (2015). Changes in systolic blood pressure over time in healthy cats and cats with chronic kidney disease. Journal of Veterinary Internal Medicine, 29(3), 855-61. https://doi.org/10.1111/jvim.12600

Determination of extracellular fluid volume in healthy and azotemic cats (2015)
Journal Article
Finch, N. C., Heiene, R., Elliott, J., Syme, H. M., & Peters, A. M. (2015). Determination of extracellular fluid volume in healthy and azotemic cats. Journal of Veterinary Internal Medicine, 29(1), 35-42. https://doi.org/10.1111/jvim.12506

Renal fibrosis in feline chronic kidney disease: known mediators and mechanisms of injury (2015)
Journal Article
Lawson, J. S., Elliott, J., Wheeler-Jones, C. P. D., Syme, H. M., & Jepson, R. E. (2015). Renal fibrosis in feline chronic kidney disease: known mediators and mechanisms of injury. https://doi.org/10.1016/j.tvjl.2014.10.009

Chronic kidney disease (CKD) is a common medical condition of ageing cats. In most cases the underlying aetiology is unknown, but the most frequently reported pathological diagnosis is renal tubulointerstitial fibrosis. Renal fibrosis, characterised... Read More about Renal fibrosis in feline chronic kidney disease: known mediators and mechanisms of injury.

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