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Potential innate immunity-related markers of endometrial receptivity and recurrent implantation failure (RIF) (2021)
Journal Article
Basatvat, S., Russell, J., Saare, M., Thurston, L., Salumets, A., & Fazeli, A. (2021). Potential innate immunity-related markers of endometrial receptivity and recurrent implantation failure (RIF). Reproductive Biology, 21(4), https://doi.org/10.1016/j.repbio.2021.100569

The successful implantation of the embryo into a receptive endometrium is essential for the establishment of a viable pregnancy while recurrent implantation failure (RIF) is a real challenge in assisted reproduction. The maternal innate immune system... Read More about Potential innate immunity-related markers of endometrial receptivity and recurrent implantation failure (RIF).

Efficient isolation, biophysical characterisation and molecular composition of extracellular vesicles secreted by primary and immortalised cells of reproductive origin (2019)
Journal Article
Jamaludin, N. A., Thurston, L. M., Witek, K. J., Meikle, A., Basatvat, S., Elliott, S., …Fazeli, A. (2019). Efficient isolation, biophysical characterisation and molecular composition of extracellular vesicles secreted by primary and immortalised cells of reproductive origin. Theriogenology, 135, 121-137. https://doi.org/10.1016/j.theriogenology.2019.06.002

Effective communication between the maternal reproductive tract, gametes and the pre-implantation embryo is essential for the successful establishment of pregnancy. Recent studies have recognised extracellular vesicles (EVs) as potent vehicles for in... Read More about Efficient isolation, biophysical characterisation and molecular composition of extracellular vesicles secreted by primary and immortalised cells of reproductive origin.

Alteration in the expression of the renin-angiotensin system in the myocardium of mice conceived by in vitro fertilization (2018)
Journal Article
Wang, Q., Zhang, Y., Le, F., Wang, N., Zhang, F., Luo, Y., …Jin, F. (2018). Alteration in the expression of the renin-angiotensin system in the myocardium of mice conceived by in vitro fertilization. Biology of Reproduction, https://doi.org/10.1093/biolre/ioy158

Epidemiological studies have revealed that offspring conceived by in vitro fertilization (IVF) have an elevated risk of cardiovascular malformations at birth, and are more predisposed to cardiovascular diseases in late childhood. Unfortunately, the u... Read More about Alteration in the expression of the renin-angiotensin system in the myocardium of mice conceived by in vitro fertilization.

Alterations in placental 11 beta-hydroxysteroid dehydrogenase (11 beta HSD) activities and fetal cortisol : cortisone ratios induced by nutritional restriction prior to conception and at defined stages of gestation in ewes
Journal Article
McMullen, S., Osgerby, J. C., Thurston, L. M., Gadd, T. S., Wood, P. J., Wathes, D. C., & Michael, A. E. Alterations in placental 11 beta-hydroxysteroid dehydrogenase (11 beta HSD) activities and fetal cortisol : cortisone ratios induced by nutritional restriction prior to conception and at defined stages of gestation in ewes. Reproduction, 127(6), 717-725. https://doi.org/10.1530/rep.1.00070

11 beta-hydroxysteroid dehydrogenase enzymes in the testis and male reproductive tract of the boar (Sus scrofa domestica) indicate local roles for glucocorticoids in male reproductive physiology
Journal Article
Sharp, V., Thurston, L. M., Fowkes, R. C., & Michael, A. E. 11 beta-hydroxysteroid dehydrogenase enzymes in the testis and male reproductive tract of the boar (Sus scrofa domestica) indicate local roles for glucocorticoids in male reproductive physiology. Reproduction, 134(3), 473-482. https://doi.org/10.1530/REP-07-0126

Ovarian modulators of type 1 11 beta-hydroxysteroid dehydrogenase (11 beta HSD) activity and intra-follicular cortisol : cortisone ratios correlate with the clinical outcome of IVF
Journal Article
Thurston, L. M., Norgate, D. P., Jonas, K. C., Gregory, L., Wood, P. J., Cooke, B. A., & Michael, A. E. Ovarian modulators of type 1 11 beta-hydroxysteroid dehydrogenase (11 beta HSD) activity and intra-follicular cortisol : cortisone ratios correlate with the clinical outcome of IVF. Human Reproduction, 18(8), 1603-1612. https://doi.org/10.1093/humrep/deg322

Ovarian modulators of 11 beta-hydroxysteroid dehydrogenase (11 beta HSD) activity in follicular fluid from bovine and porcine large antral follicles and spontaneous ovarian cysts
Journal Article
Thurston, L. M., Jonas, K. C., Abayasekara, D. R. E., & Michael, A. E. Ovarian modulators of 11 beta-hydroxysteroid dehydrogenase (11 beta HSD) activity in follicular fluid from bovine and porcine large antral follicles and spontaneous ovarian cysts. Biology of Reproduction, 68(6), 2157-2163. https://doi.org/10.1095/biolreprod.102.012096