Comparison of the effects of dietary n-3 and n-6 polyunsaturated fatty acids on very-low-density lipoprotein secretion when delivered to hepatocytes in chylomicron remnants
Journal Article
Zheng, X. Z., Avella, M. A., & Botham, K. M. Comparison of the effects of dietary n-3 and n-6 polyunsaturated fatty acids on very-low-density lipoprotein secretion when delivered to hepatocytes in chylomicron remnants. Biochemical Journal, 357, 481-487. https://doi.org/10.1042/0264-6021%3A3570481
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The internal redox balance of the cells influences the metabolism of lipids of dietary origin by J774 macrophages: Implications for foam cell formation
Journal Article
Napolitano, M., Rivabene, R., Avella, M. A., Botham, K. M., & Bravo, E. The internal redox balance of the cells influences the metabolism of lipids of dietary origin by J774 macrophages: Implications for foam cell formation. Journal of Vascular Research, 38(4), 350-360. https://doi.org/10.1159/000051066
Oxidation affects the regulation of hepatic lipid synthesis by chylomicron remnants
Journal Article
Napolitano, M., Rivabene, R., Avella, M. A., Amicone, L., Tripodi, M., Botham, K. M., & Bravo, E. Oxidation affects the regulation of hepatic lipid synthesis by chylomicron remnants. Free Radical Biology and Medicine, 30(5), 506-515. https://doi.org/10.1016/S0891-5849%2800%2900493-7
Lipid synthesis in macrophages derived from the human cell line THP-1: modulation of the effects of native and oxidized chylomicron-remnant-like particles by oestrogen
Journal Article
Napolitano, M., Batt, K. V., Avella, M. A., Bravo, E., & Botham, K. M. Lipid synthesis in macrophages derived from the human cell line THP-1: modulation of the effects of native and oxidized chylomicron-remnant-like particles by oestrogen. Clinical Science, 101(4), 403-413. https://doi.org/10.1042/CS20010086
The fatty acid composition of chylomicron remnants influences their binding and internalization by isolated hepatocytes
Journal Article
Lambert, M. S., Avella, M. A., Berhane, Y., Shervill, E., & Botham, K. M. The fatty acid composition of chylomicron remnants influences their binding and internalization by isolated hepatocytes. European Journal of Biochemistry, 268(14), 3983-3992
The differential hepatic uptake of chylomicron remnants of different fatty acid composition is not mediated by hepatic lipase
Journal Article
Lambert, M. S., Avella, M. A., Berhane, Y., Shervill, E., & Botham, K. M. The differential hepatic uptake of chylomicron remnants of different fatty acid composition is not mediated by hepatic lipase. British Journal of Nutrition, 85, 575-582. https://doi.org/10.1079/BJN2000328
Metabolism of chylomicron cholesterol is delayed by estrogen. An in vivo study in the rat
Journal Article
Bravo, E., Cantafora, A., Avella, M. A., & Botham, K. M. Metabolism of chylomicron cholesterol is delayed by estrogen. An in vivo study in the rat. Experimental Biology and Medicine, 226(2), 112-118
The influence of chylomicron remnants on cholesteryl ester metabolism in cultured rat hepatocytes: comparison of the effects of particles enriched in n-3 or n-6 polyunsaturated fatty acids
Journal Article
Botham, K. M., Maldonado, E. N., Chico, Y., Zheng, X. Z., Avella, M. A., & Ochoa, B. The influence of chylomicron remnants on cholesteryl ester metabolism in cultured rat hepatocytes: comparison of the effects of particles enriched in n-3 or n-6 polyunsaturated fatty acids
The effects of chylomicron remnants enriched in n-3 or n-6 polyunsaturated fatty acids on the transcription of genes regulating their uptake and metabolism by the liver: Influence of cellular oxidative state
Journal Article
Zheng, X. Z., Rivabene, R., Cavallari, C., Napolitano, M., Avella, M. A., Bravo, E., & Botham, K. M. The effects of chylomicron remnants enriched in n-3 or n-6 polyunsaturated fatty acids on the transcription of genes regulating their uptake and metabolism by the liver: Influence of cellular oxidative state. Free Radical Biology and Medicine, 32(11), 1123-1131
Chylomicron-remnant-like particles inhibit receptor-mediated endothelium-dependent vasorelaxation in pig coronary arteries
Journal Article
Goulter, A. B., Avella, M. A., Elliott, J., & Botham, K. M. Chylomicron-remnant-like particles inhibit receptor-mediated endothelium-dependent vasorelaxation in pig coronary arteries. Clinical Science, 103(5), 451-460
Incorporation of lycopene into chylomicron remnant-like particles enhances their induction of lipid accumulation in macrophages
Journal Article
Moore, E. H., Napolitano, M., Prosperi, A., Avella, M. A., Suckling, K. E., Bravo, E., & Botham, K. M. Incorporation of lycopene into chylomicron remnant-like particles enhances their induction of lipid accumulation in macrophages. Biochemical and Biophysical Research Communications, 312(4), 1216-1219. https://doi.org/10.1016/j.bbrc.2003.11.040
Chylomicron-remnant-like particles inhibit the basal nitric oxide pathway in porcine coronary artery and aortic endothelial cells
Journal Article
Goulter, A. B., Avella, M. A., Botham, K. M., & Elliott, J. Chylomicron-remnant-like particles inhibit the basal nitric oxide pathway in porcine coronary artery and aortic endothelial cells. Clinical Science, 105(3), 363-371. https://doi.org/10.1042/CS20030039
The effects of dietary n-3 polyunsaturated fatty acids delivered in chylomicron remnants on the transcription of genes regulating synthesis and secretion of very-low-density lipoprotein by the liver: Modulation by cellular oxidative state
Journal Article
Botham, K. M., Zheng, X. Z., Napolitano, M., Avella, M. A., Cavallari, C., Rivabene, R., & Bravo, E. The effects of dietary n-3 polyunsaturated fatty acids delivered in chylomicron remnants on the transcription of genes regulating synthesis and secretion of very-low-density lipoprotein by the liver: Modulation by cellular oxidative state. Experimental Biology and Medicine, 228(2), 143-151
The fatty acid composition of chylomicron remnants influences their propensity to oxidate
Journal Article
Napolitano, M., Bravo, E., Avella, M. A., Chico, Y., Ochoa, B., Botham, K. M., & Rivabene, R. The fatty acid composition of chylomicron remnants influences their propensity to oxidate
Cholesterol esterification in human monocyte-derived macrophages is inhibited by protein kinase C with dual roles for mitogen activated protein kinases
Journal Article
Napolitano, M., Avella, M., Goode, N. T., Botham, K. M., & Bravo, E. Cholesterol esterification in human monocyte-derived macrophages is inhibited by protein kinase C with dual roles for mitogen activated protein kinases. Cell Biology International, 28(10), 717-725. https://doi.org/10.1016/j.cellbi.2004.07.007
Protection of chylomicron remnants from oxidation by incorporation of probucol into the particles enhances their uptake by human macrophages and increases lipid accumulation in the cells
Journal Article
Moore, E. H., Napolitano, M., Avella, M. A., Bejta, F., Suckling, K. E., Bravo, E., & Botham, K. M. Protection of chylomicron remnants from oxidation by incorporation of probucol into the particles enhances their uptake by human macrophages and increases lipid accumulation in the cells. European Journal of Biochemistry, 271(12), 2417-2427. https://doi.org/10.1111/j.1432-1033.2004.04164.x
Differential effects of low-density lipoprotein and chylomicron remnants on lipid accumulation in human macrophages
Journal Article
Batt, K. V., Avella, M. A., Moore, E. H., Jackson, B. F., Suckling, K. E., & Botham, K. M. Differential effects of low-density lipoprotein and chylomicron remnants on lipid accumulation in human macrophages. Experimental Biology and Medicine, 229(6), 528-537
The role of protein kinase C in regulating equine eosinophil adherence and superoxide production
Journal Article
Sepulveda, M. F., Greenaway, E. C., Avella, M. A., Goode, N. T., & Cunningham, F. M. The role of protein kinase C in regulating equine eosinophil adherence and superoxide production. Inflammation Research, 54(3), 97-105. https://doi.org/10.1007/s00011-004-1329-2
Efflux of lipid from macrophages after induction of lipid accumulation by chylomicron remnants
Journal Article
Moore, E. H., Bejta, F., Avella, M. A., Suckling, K. E., & Botham, K. M. Efflux of lipid from macrophages after induction of lipid accumulation by chylomicron remnants. https://doi.org/10.1016/j.bbalip.2005.04.009
Uptake of triacylglycerol-rich lipoproteins of differing triacylglycerol molecular species and unsaponifiable content by liver cells
Journal Article
Perona, J. S., Avella, M. A., Botham, K. M., & Ruiz-Gutierrez, V. Uptake of triacylglycerol-rich lipoproteins of differing triacylglycerol molecular species and unsaponifiable content by liver cells. British Journal of Nutrition, 95(5), 889-897. https://doi.org/10.1079/BJN20061730