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Laminitis in horses
Journal Article
Menzies-Gow, N. J. (in press). Laminitis in horses. Veterinary Record, 183(16), 505-506. https://doi.org/10.1136/inp.k4485

Laminitis is a common and painful condition of adult equids that often results in permanent lameness or euthanasia. In recent years, our knowledge of the condition has developed and this article discusses the current understanding of laminitis and ap... Read More about Laminitis in horses.

LRRK2 deficiency induced mitochondrial Ca2+ efflux inhibition can be rescued by Na+/Ca2+/Li+ exchanger upregulation
Journal Article
Ludtmann, M. H. R., Kostic, M., Horne, A., Gandhi, S., Sekler, I., & Abramov, A. Y. (in press). LRRK2 deficiency induced mitochondrial Ca2+ efflux inhibition can be rescued by Na+/Ca2+/Li+ exchanger upregulation. https://doi.org/10.1038/s41419-019-1469-5

Variants of leucine-rich repeat kinase 2 (lrrk2) are associated with an increased risk in developing Parkinson’s disease (PD). Mitochondrial dysfunction and specifically mitochondrial Ca2+ handling has been linked to the pathogenesis of PD. Here we d... Read More about LRRK2 deficiency induced mitochondrial Ca2+ efflux inhibition can be rescued by Na+/Ca2+/Li+ exchanger upregulation.