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Monoacylated Cellular Prion Proteins Reduce Amyloid-beta-Induced Activation of Cytoplasmic Phospholipase A2 and Synapse Damage
Journal Article
West, E., Osborne, C., Nolan, W., & Bate, C. (in press). Monoacylated Cellular Prion Proteins Reduce Amyloid-beta-Induced Activation of Cytoplasmic Phospholipase A2 and Synapse Damage. Biology, 4(2), 367-82. https://doi.org/10.3390/biology4020367

Alzheimer’s disease (AD) is a progressive neurodegenerative disease characterized by the accumulation of amyloid-β (Aβ) and the loss of synapses. Aggregation of the cellular prion protein (PrPC) by Aβ oligomers induced synapse damage in cultured neur... Read More about Monoacylated Cellular Prion Proteins Reduce Amyloid-beta-Induced Activation of Cytoplasmic Phospholipase A2 and Synapse Damage.

Effect of the synthetic Toll-like receptor ligands LPS, Pam3CSK4, HKLM and FSL-1 in the function of bovine polymorphonuclear neutrophils
Journal Article
Conejeros, I., Gibson, A. J., Werling, D., Munoz-Caro, T., Hermosilla, C., Taubert, A., & Burgos, R. A. (in press). Effect of the synthetic Toll-like receptor ligands LPS, Pam3CSK4, HKLM and FSL-1 in the function of bovine polymorphonuclear neutrophils. Developmental and Comparative Immunology, 52(2), 215-225. https://doi.org/10.1016/j.dci.2015.05.012

Toll-like receptors (TLR) are a family of pattern recognition receptors that sense microbial associated molecular patterns (MAMP) such as microbial membrane components and nucleic acids of bacterial origin. Polymorphonuclear neutrophils (PMN) are the... Read More about Effect of the synthetic Toll-like receptor ligands LPS, Pam3CSK4, HKLM and FSL-1 in the function of bovine polymorphonuclear neutrophils.

a-Synuclein-Induced Synapse Damage in Cultured Neurons Is Mediated by Cholesterol-Sensitive Activation of Cytoplasmic Phospholipase A2
Journal Article
Bate, C., & Williams, A. (in press). a-Synuclein-Induced Synapse Damage in Cultured Neurons Is Mediated by Cholesterol-Sensitive Activation of Cytoplasmic Phospholipase A2. Biomolecules, 5(1), 178-93. https://doi.org/10.3390/biom5010178

The accumulation of aggregated forms of the α-synuclein (αSN) is associated with the pathogenesis of Parkinson’s disease (PD) and Dementia with Lewy Bodies. The loss of synapses is an important event in the pathogenesis of these diseases. Here we sho... Read More about a-Synuclein-Induced Synapse Damage in Cultured Neurons Is Mediated by Cholesterol-Sensitive Activation of Cytoplasmic Phospholipase A2.

Prevalence of theileria equi and babesia caballi as well as the identification of associated ticks in sympatric grevy's zebras (equus grevyi) and donkeys (equus africanus asinus) in northern kenya
Journal Article
Hawkins, E., Kock, R. A., McKeever, D. J., Gakuya, F., Musyoki, C., Chege, S. M., …Maina, E. Prevalence of theileria equi and babesia caballi as well as the identification of associated ticks in sympatric grevy's zebras (equus grevyi) and donkeys (equus africanus asinus) in northern kenya. https://doi.org/10.7589/2013-11-316