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Bats actively modulate membrane compliance to control camber and reduce drag (2022)
Journal Article
Cheney, J., Rehm, J., Swartz, S., & Breuer, K. (in press). Bats actively modulate membrane compliance to control camber and reduce drag. Journal of Experimental Biology, https://doi.org/10.1242/jeb.243974

Bat wing skin is exceptionally compliant and cambers significantly during flight. Plagiopatagiales proprii, arrays of small muscles embedded in the armwing membrane, are activated during flight and are hypothesized to modulate membrane tension. We ex... Read More about Bats actively modulate membrane compliance to control camber and reduce drag.

A food systems approach and qualitative system dynamics model to reveal policy issues within the commercial broiler chicken system in South Africa (2022)
Journal Article
Queenan, K., Cuevas, S., Mabhaudhi, T., Chimonyo, M., Shankar, B., Slotow, R., & Häsler, B. (in press). A food systems approach and qualitative system dynamics model to reveal policy issues within the commercial broiler chicken system in South Africa. PLoS ONE, https://doi.org/10.1371/journal.pone.0270756

Abstract: Global broiler production and consumption levels continue to rise. South Africa’s broiler system is dominated by commercial production and formal retail trade, with competition from cheap imports. Local broiler policies have narrow, produc... Read More about A food systems approach and qualitative system dynamics model to reveal policy issues within the commercial broiler chicken system in South Africa.

The immunomodulatory effects of statins on macrophages Author information (2022)
Journal Article
Sheridan, A., Wheeler-Jones, C., & Gage, M. C. (2022). The immunomodulatory effects of statins on macrophages Author information. Immuno, https://doi.org/10.3390/immuno2020021

Statins are extensively used in the medical practice, with their action as lipid-lowering agents proving to be central in the treatment of atherosclerotic cardiovascular disease. However, in addition to their cholesterol-reducing effects, mounting ev... Read More about The immunomodulatory effects of statins on macrophages Author information.

A novel whole yeast-based subunit oral vaccine against Eimeria tenella in chickens (2022)
Journal Article
Soutter, F., Werling, D., Nolan, M., Küster, T., Attree, E., Marugán-Hernández, V., …Blake, D. (2022). A novel whole yeast-based subunit oral vaccine against Eimeria tenella in chickens. Frontiers in Immunology, 13, Article 809711. https://doi.org/10.3389/fimmu.2022.809711

Cheap, easy-to-produce oral vaccines are needed for control of coccidiosis in chickens to reduce the impact of this disease on welfare and economic performance. Saccharomyces cerevisiae yeast expressing three Eimeria tenella antigens were developed a... Read More about A novel whole yeast-based subunit oral vaccine against Eimeria tenella in chickens.

Longitudinal assessment of blood-borne musculoskeletal disease biomarkers in the DE50-MD dog model of Duchenne muscular dystrophy (2022)
Journal Article
Riddell, D. O., Hildyard, J. C. W., Harron, R. C. M., Wells, D. J., & Piercy, R. J. (in press). Longitudinal assessment of blood-borne musculoskeletal disease biomarkers in the DE50-MD dog model of Duchenne muscular dystrophy. Wellcome Open Research, https://doi.org/10.12688/wellcomeopenres.17398.1

Background: Duchenne muscular dystrophy (DMD) is a fatal muscle wasting disease affecting approximately 1 in 6000 male births worldwide. Due to their phenotypic similarity to human patients, large animal models are invaluable tools for pre-clinical t... Read More about Longitudinal assessment of blood-borne musculoskeletal disease biomarkers in the DE50-MD dog model of Duchenne muscular dystrophy.

Probing differences in gene essentiality between the human and animal adapted (2021)
Journal Article
Gibson, A. J., Passmore, I. J., Faulkner, V., Xia, D., Nobeli, I., Stiens, J., …Kendall, S. L. (2021). Probing differences in gene essentiality between the human and animal adapted. Frontiers in Veterinary Science,

Members of the Mycobacterium tuberculosis complex (MTBC) show distinct host adaptations, preferences and phenotypes despite being >99% identical at the nucleic acid level. Previous studies have explored gene expression changes between the members, ho... Read More about Probing differences in gene essentiality between the human and animal adapted.

Associations between Circulating IGF-1 Concentrations and Disease Status with the Leukocyte Transcriptome in Early Lactation Dairy Cows (2021)
Journal Article
Wathes, D. C., Becker, F., Buggiotti, L., Crowe, M. A., Ferris, C., Foldager, L., …GplusE consortium. (2021). Associations between Circulating IGF-1 Concentrations and Disease Status with the Leukocyte Transcriptome in Early Lactation Dairy Cows. Animals,

Peripartum dairy cows commonly experience negative energy balance (EB) and immunosuppression together with high incidences of infectious and metabolic disease. This study investigated mechanisms linking EB status with immune defence in early lactatio... Read More about Associations between Circulating IGF-1 Concentrations and Disease Status with the Leukocyte Transcriptome in Early Lactation Dairy Cows.

Estimating gaits of an ancient crocodile-line archosaur through 1 trajectory optimization, with comparison to fossil trackways (2021)
Journal Article
Polet, D. T., & Hutchinson, J. R. (in press). Estimating gaits of an ancient crocodile-line archosaur through 1 trajectory optimization, with comparison to fossil trackways. Frontiers in Bioengineering and Biotechnology, https://doi.org/10.3389/fbioe.2021.800311

13 Fossil trackways provide a glimpse into the behaviour of extinct animals. However, while providing 14 information of trackmaker size, stride and even speed, the actual gait of the organism can be 15 ambiguous. This is especially true of quadrupeda... Read More about Estimating gaits of an ancient crocodile-line archosaur through 1 trajectory optimization, with comparison to fossil trackways.

A genome-wide association study identifies novel candidate genes for susceptibility to diabetes mellitus in non-obese cats (2021)
Journal Article
Catchpole, B., Forcada, Y., Boursnell, M., & Church, D. (2021). A genome-wide association study identifies novel candidate genes for susceptibility to diabetes mellitus in non-obese cats. PLoS ONE, https://doi.org/10.1371/journal.pone.0259939

Diabetes mellitus (DM) is a common feline endocrinopathy, which is similar to human type 2 diabetes (T2DM) in terms of its pathophysiology. T2DM occurs due to peripheral insulin resistance and/or ?-cell dysfunction. Several studies have identified ge... Read More about A genome-wide association study identifies novel candidate genes for susceptibility to diabetes mellitus in non-obese cats.

Time to Loss of Behavioural and Brainstem Responses of Ducks Following Non-Stunned Slaughter (2021)
Journal Article
Gibson, T. (in press). Time to Loss of Behavioural and Brainstem Responses of Ducks Following Non-Stunned Slaughter. Animals, https://doi.org/10.3390/ani11123531

Non-stunned slaughter has been extensively described for other farmed species but there has been limited research on waterfowl. The study assessed 34 ducks in a non-stunned halal slaughter-house in Brazil for time to loss of consciousness using vario... Read More about Time to Loss of Behavioural and Brainstem Responses of Ducks Following Non-Stunned Slaughter.

Evaluating integrated surveillance for antimicrobial use and resistance in England: a qualitative study (2021)
Journal Article
Bennani, H., Cornelsen, L., Stärk, K. D. C., & Häsler, B. (2021). Evaluating integrated surveillance for antimicrobial use and resistance in England: a qualitative study. Frontiers in Veterinary Science,

Integrated surveillance systems for antimicrobial use (AMU) and antimicrobial resistance (AMR) require regular evaluation to ensure the effectiveness and efficiency of the system. An important step in the evaluation is to choose an appropriate tool... Read More about Evaluating integrated surveillance for antimicrobial use and resistance in England: a qualitative study.

Histopathologic Concordance Of Concurrent Duodenal And Ileal Biopsy Specimens In Dogs With Inflammatory Or Neoplastic Disease Blinded (2021)
Journal Article
Kathrani, A., Priestnall, S., & Caulfield, S. (2021). Histopathologic Concordance Of Concurrent Duodenal And Ileal Biopsy Specimens In Dogs With Inflammatory Or Neoplastic Disease Blinded. Journal of Veterinary Internal Medicine, https://doi.org/10.3390/ani11102938

Background Histopathologic discordance between intestinal locations in canine chronic enteropathy has prompted recommendations to biopsy both duodenal and ileal sites to minimize lesion oversight. Further evaluation is required for dogs with non-chr... Read More about Histopathologic Concordance Of Concurrent Duodenal And Ileal Biopsy Specimens In Dogs With Inflammatory Or Neoplastic Disease Blinded.

Comparison of the transcriptome in circulating leukocytes in early lactation between primiparous and multiparous cows provides evidence for age-related changes (2021)
Journal Article
Buggiotti, L., Cheng, Z., Salavati, M., Wathes, C., & GplusE Consortium. (2021). Comparison of the transcriptome in circulating leukocytes in early lactation between primiparous and multiparous cows provides evidence for age-related changes. BMC Genomics, https://doi.org/10.1186/s12864-021-07977-5

Background: Previous studies have identified many immune pathways which are consistently altered in humans and model organisms as they age. Dairy cows are often culled at quite young ages due to an inability to cope adequately with metabolic and infe... Read More about Comparison of the transcriptome in circulating leukocytes in early lactation between primiparous and multiparous cows provides evidence for age-related changes.

Controlling the causative agents of coccidiosis in domestic chickens; an eye on the 1 past and considerations for the future 2 (2021)
Journal Article
Attree, E., Sanchez-Arsuaga, G., Jones, M., Xia, D., -Hernandez, M., Blake, D., & Tomley, F. (2021). Controlling the causative agents of coccidiosis in domestic chickens; an eye on the 1 past and considerations for the future 2. CAB Reviews: Perspectives in Agriculture, Veterinary Science, Nutrition and Natural Resources, https://doi.org/10.1186/s43170-021-00056-5

Coccidiosis is a potentially severe enteritis caused by species of obligate intracellular parasites of the genus Eimeria. These parasites cause significant economic losses to the poultry industry, predominantly due to compromised efficiency of produc... Read More about Controlling the causative agents of coccidiosis in domestic chickens; an eye on the 1 past and considerations for the future 2.

The critical dynamic role of the tail in bipedal dinosaur locomotion (2021)
Journal Article
Bishop, P., Falisse, A., De Groote, F., & Hutchinson, J. (2021). The critical dynamic role of the tail in bipedal dinosaur locomotion. Science Advances, https://doi.org/10.1126/sciadv.abi7348

Locomotion has influenced the ecology, evolution, and extinction of species throughout history, yet studying locomotion in the fossil record is challenging. Computational biomechanics can provide novel insight by mechanistically relating observed ana... Read More about The critical dynamic role of the tail in bipedal dinosaur locomotion.

CD146 Delineates an Interfascicular Cell Sub-Population in Tendon That Is Recruited during Injury through Its Ligand Laminin-?4 (2021)
Journal Article
Marr, N., Meeson, R., Kelly, E., Fang, Y., Peffers, M., Pitsillides, A., …Thorpe, C. (2021). CD146 Delineates an Interfascicular Cell Sub-Population in Tendon That Is Recruited during Injury through Its Ligand Laminin-α4. International Journal of Molecular Sciences, https://doi.org/10.3390/ijms22189729

The interfascicular matrix (IFM) binds tendon fascicles and contains a population of morphologically distinct cells; however the role of IFM-localised cell populations in tendon repair remains to be determined. The basement membrane protein laminin-?... Read More about CD146 Delineates an Interfascicular Cell Sub-Population in Tendon That Is Recruited during Injury through Its Ligand Laminin-?4.