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Regional variations in discrete collagen fibre mechanics within intact intervertebral disc resolved using synchrotron computed tomography and digital volume correlation (2022)
Journal Article
Disney, C., Mo, J., Eckersley, A., Bodey, A., Hoyland, J., Sherratt, M., …Bay, B. (2022). Regional variations in discrete collagen fibre mechanics within intact intervertebral disc resolved using synchrotron computed tomography and digital volume correlation. Acta Biomaterialia, 138, 361-374. https://doi.org/10.1016/j.actbio.2021.10.012

Many soft tissues, such as the intervertebral disc (IVD), have a hierarchical fibrous composite structure which suffers from regional damage. We hypothesise that these tissue regions have distinct, inherent fibre structure and structural response upo... Read More about Regional variations in discrete collagen fibre mechanics within intact intervertebral disc resolved using synchrotron computed tomography and digital volume correlation.

Use of multivariate analysis to evaluate antigenic relationships between US BVDV vaccine strains and non-US genetically divergent isolates (2022)
Journal Article
Mosena, A., Falkenberg, S., Ma, H., Casas, E., Dassanayake, R., Booth, R., …Neill, J. (2022). Use of multivariate analysis to evaluate antigenic relationships between US BVDV vaccine strains and non-US genetically divergent isolates. Journal of Virological Methods, 299, https://doi.org/10.1016/j.jviromet.2021.114328

Bovine viral diarrhea virus (BVDV) comprises two species, BVDV-1 and BVDV-2. But given the genetic diversity among pestiviruses, at least 22 subgenotypes are described for BVDV-1 and 3-4 for BVDV-2. Genetic characterization is generally accomplished... Read More about Use of multivariate analysis to evaluate antigenic relationships between US BVDV vaccine strains and non-US genetically divergent isolates.

Investigation Of Factors Affecting Recruitment And Retention In The UK Veterinary Nursing Profession (2022)
Journal Article
Hagen, J., Weller, R., Mair, T., Batt-Williams, S., & Kinnison, T. (2022). Investigation Of Factors Affecting Recruitment And Retention In The UK Veterinary Nursing Profession. Vet Record Case Reports, https://doi.org/10.1136/vr.106044

Background Recruitment and retention have been identified as contributing factors to workforce shortages in the veterinary team. Methods In this second part of a project exploring recruitment and retention in veterinary professions, results from v... Read More about Investigation Of Factors Affecting Recruitment And Retention In The UK Veterinary Nursing Profession.

Occurrence and clinical management of urethral obstruction in male cats under primary veterinary care in the United Kingdom in 2016 (2022)
Journal Article
Beeston, D., Humm, K., Church, D. B., Brodbelt, D., & O'Neill, D. G. (in press). Occurrence and clinical management of urethral obstruction in male cats under primary veterinary care in the United Kingdom in 2016. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.16389

Background: Urethral obstruction (UO) has a negative effect on welfare of cats. Objectives: This study aimed to determine incidence, case management, and outcomes of UO in cats in primary-care practice in the United Kingdom. Animals: All male c... Read More about Occurrence and clinical management of urethral obstruction in male cats under primary veterinary care in the United Kingdom in 2016.

Prospective evaluation of novel biomarkers of acute kidney injury in dogs following cardiac surgery under cardiopulmonary bypass (2022)
Journal Article
Starybrat, D., Jepson, R., Bristow, P., Peterson, S., Yerramilli, M., Yerramilli, M., …Cortellini, S. (in press). Prospective evaluation of novel biomarkers of acute kidney injury in dogs following cardiac surgery under cardiopulmonary bypass. Journal of Veterinary Emergency and Critical Care,

Objective - Assess the occurrence of acute kidney injury (AKI) in dogs undergoing cardiac surgery under cardiopulmonary bypass (CPB) and explore associations between traditional and novel serum and urinary biomarkers. Design – Prospective cohort st... Read More about Prospective evaluation of novel biomarkers of acute kidney injury in dogs following cardiac surgery under cardiopulmonary bypass.

Training related risk factors for Exercise Induced Pulmonary Haemorrhage in British National Hunt racehorses. (2022)
Journal Article
Cardwell, J., & McGilvray, T. (in press). Training related risk factors for Exercise Induced Pulmonary Haemorrhage in British National Hunt racehorses. Equine Veterinary Journal, https://doi.org/10.1111/evj.13448

Background: Exercise induced pulmonary haemorrhage (EIPH) is an important condition of horses performing high intensity exercise, with reported prevalence among racehorses of up to 95%, based on the detection of blood on tracheobronchoscopy. Previous... Read More about Training related risk factors for Exercise Induced Pulmonary Haemorrhage in British National Hunt racehorses..

Disease prevention efforts on Welsh cattle farms are influenced by farm demographics (2022)
Journal Article
Paton, N., Schaefer, K., Armitage-Chan, E., Cooper, H., & Buggiotti, L. (2022). Disease prevention efforts on Welsh cattle farms are influenced by farm demographics. Veterinary Record, https://doi.org/10.1002/vetr.1389

Background This research seeks to understand how the transition to a new generation of younger, more diverse farmers affects disease prevention efforts on UK farms. Methods We apply multivariate regression analysis to analyse survey responses from 11... Read More about Disease prevention efforts on Welsh cattle farms are influenced by farm demographics.

Dietary and agricultural adaptations to drought among smallholder farmers in South Africa: A qualitative study (2022)
Journal Article
Hawkins, P., Geza, W., Mabhaudhi, T., Sutherland, C., Queenan, K., Dangour, A., & Scheelbeek, P. (2022). Dietary and agricultural adaptations to drought among smallholder farmers in South Africa: A qualitative study. Weather and Climate Extremes, 35, 100413. https://doi.org/10.1016/j.wace.2022.100413

Building resilience to environmental change is an integral part of long-term climate adaptation planning and local policy. There is an increased understanding of the impact of climate change on global crop production however, little focus has been gi... Read More about Dietary and agricultural adaptations to drought among smallholder farmers in South Africa: A qualitative study.

A novel whole yeast-based subunit oral vaccine against Eimeria tenella in chickens (2022)
Journal Article
Soutter, F., Werling, D., Nolan, M., Küster, T., Attree, E., Marugán-Hernández, V., …Blake, D. (2022). A novel whole yeast-based subunit oral vaccine against Eimeria tenella in chickens. Frontiers in Immunology, 13, Article 809711. https://doi.org/10.3389/fimmu.2022.809711

Cheap, easy-to-produce oral vaccines are needed for control of coccidiosis in chickens to reduce the impact of this disease on welfare and economic performance. Saccharomyces cerevisiae yeast expressing three Eimeria tenella antigens were developed a... Read More about A novel whole yeast-based subunit oral vaccine against Eimeria tenella in chickens.

Caudal foot placement superior to toe elevation for navicular palmaroproximal-palmarodistal-oblique image quality (2022)
Journal Article
Peeters, M. W., Thursby, J. J., Watson, H. E., & Berner, D. (2022). Caudal foot placement superior to toe elevation for navicular palmaroproximal-palmarodistal-oblique image quality. Equine Veterinary Journal, https://doi.org/10.1111/evj.13563

Background: Palmaroproximal-palmarodistal oblique (PaPr-PaDiO) radiographs are regularly obtained for full evaluation of the navicular bone (NB). Despite their routine use, different acquisition techniques are described. Objectives: Determining the... Read More about Caudal foot placement superior to toe elevation for navicular palmaroproximal-palmarodistal-oblique image quality.

Breed and conformational predispositions for prolapsed nictitating membrane gland (PNMG) in dogs in the UK: A VetCompass study (2022)
Journal Article
O'Neill, D., Yahui, Y., Roser, T. P., Dave C., B., David B., C., Camilla, P., & Minn, M. (2022). Breed and conformational predispositions for prolapsed nictitating membrane gland (PNMG) in dogs in the UK: A VetCompass study. (Con)textos Linguísticos, 17(1), https://doi.org/10.1371/journal.pone.0260538

Background Prolapsed nictitating membrane gland (PNMG) is the most common disorder of the third eyelid in dogs. However, the epidemiology of PNMG in the wider dog population remains understudied. Methods Using de-identified clinical data from th... Read More about Breed and conformational predispositions for prolapsed nictitating membrane gland (PNMG) in dogs in the UK: A VetCompass study.

Effects of between and within herd moves on the shedding of recrudescent elephant endotheliotropic herpesvirus (EEHV) in captive Asian elephants (Elephas maximus) (2022)
Journal Article
Titus, S., Patterson, S., Prince-Wright, J., Dastjerdi, A., & Molenaar, F. (2022). Effects of between and within herd moves on the shedding of recrudescent elephant endotheliotropic herpesvirus (EEHV) in captive Asian elephants (Elephas maximus). Viruses, https://doi.org/10.3390/v14020229

Haemorrhagic disease associated with elephant endotheliotropic herpesvirus (Elephantid her-pesvirus, EEHV) infections is the leading cause of death for Asian elephant (Elephas maximus) calves. This study assessed the effect of captive herd management... Read More about Effects of between and within herd moves on the shedding of recrudescent elephant endotheliotropic herpesvirus (EEHV) in captive Asian elephants (Elephas maximus).

Ultrasonography as a sensitive and specific diagnostic modality for the detection of ectopic ureters in urinary incontinent dogs (2022)
Journal Article
Taylor, O., Knight, R., Genain, M., & Owen, L. (2022). Ultrasonography as a sensitive and specific diagnostic modality for the detection of ectopic ureters in urinary incontinent dogs. Veterinary Radiology and Ultrasound, https://doi.org/10.1111/vru.13055

Ultrasonography is a widely available diagnostic modality for the identification of dogs with suspected ureteral ectopia; however published studies detailing its sensitivity and specificity are currently lacking. The aim of this retrospective, descri... Read More about Ultrasonography as a sensitive and specific diagnostic modality for the detection of ectopic ureters in urinary incontinent dogs.

Risk factors and implications associated with renal mineralization in chronic kidney disease in cats (2022)
Journal Article
Tang, P., Jepson, R., Chang, Y., Geddes, R., Hopkinson, M., & Elliott, J. (2022). Risk factors and implications associated with renal mineralization in chronic kidney disease in cats. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.16363

Background Nephrocalcinosis is a pathological feature of chronic kidney disease (CKD). Its pathophysiological implications for cats with CKD are unexplored. Objectives Identify nephrocalcinosis risk factors and evaluate its influence on CKD prog... Read More about Risk factors and implications associated with renal mineralization in chronic kidney disease in cats.

Severe thrombocytopenia due to subinvolution of placental sites in a Maltese terrier (2022)
Journal Article
Crosby, J., Plested, M., Hardas, A., & Olivares, G. (in press). Severe thrombocytopenia due to subinvolution of placental sites in a Maltese terrier. Vet Record Case Reports, https://doi.org/10.1002/vrc2.288

A 6-year 2-month, primiparous, female, entire Maltese terrier presented 4 weeks after whelping with an acute history of lethargy and vulval haemorrhage. It was found to be anaemic and severely thrombocytopenic, which raised the concern about thromboc... Read More about Severe thrombocytopenia due to subinvolution of placental sites in a Maltese terrier.

Validation of DE50-MD dogs as a model for the cognitive and biochemical defects in the brain phenotype of Duchenne muscular dystrophy (2022)
Journal Article
Crawford, A., Hildyard, J., Rushing, S., Wells, D., Diez Leon, M., & Piercy, R. (in press). Validation of DE50-MD dogs as a model for the cognitive and biochemical defects in the brain phenotype of Duchenne muscular dystrophy. eLife, https://doi.org/10.1242/dmm.049291

Duchenne muscular dystrophy (DMD), a fatal musculoskeletal disorder, is associated with neurodevelopmental problems and cognitive impairment caused by dystrophin deficiency in the brain. Dog models of DMD represent key translational tools to study... Read More about Validation of DE50-MD dogs as a model for the cognitive and biochemical defects in the brain phenotype of Duchenne muscular dystrophy.

Veterinary drug therapies used for undesirable behaviours in UK dogs under primary veterinary care (2022)
Journal Article
Pegram, C., Craven, A., Packer, R., Jarvis, S., McGreevy, P., Warnes, C., …O'Neill, D. (in press). Veterinary drug therapies used for undesirable behaviours in UK dogs under primary veterinary care. PLoS ONE, 17, https://doi.org/10.1371/journal.pone.0261139

Undesirable behaviours (UBs) in dogs are common and important issues with serious potential welfare consequences for both the dogs and their owners. This study aimed to investigate the usage of drug therapy for UBs in dogs and assess demographic risk... Read More about Veterinary drug therapies used for undesirable behaviours in UK dogs under primary veterinary care.

Risk factors associated with short-term mortality and recurrence of status epilepticus in dogs (2022)
Journal Article
Fentem, R., de Stefani, A., Quintana, R., Alcoverro, E., Jones, G., Amengual-Batle, P., & Goncalves, R. (2022). Risk factors associated with short-term mortality and recurrence of status epilepticus in dogs. Journal of Veterinary Internal Medicine, https://doi.org/10.1111/jvim.16353

Background Status epilepticus (SE) is an emergency associated with serious consequences for both patient and owner. Data regarding risk factors for short-term mortality or recurrence in dogs with SE is limited. Objective Identify risk factors associa... Read More about Risk factors associated with short-term mortality and recurrence of status epilepticus in dogs.

Surveillance of heat-related illness in small animals presenting to veterinary practices in the UK between 2013-2018. (2022)
Journal Article
Hall, E. (2022). Surveillance of heat-related illness in small animals presenting to veterinary practices in the UK between 2013-2018. Open Veterinary Journal, https://doi.org/10.5455/OVJ.2022.v12.i1.2

Background: Heat-related illness (HRI) can affect all companion animals and is likely to become more common as global temperatures rise. The misconception that HRI is primarily a result of dogs being trapped in hot cars, highlights a lack of awarenes... Read More about Surveillance of heat-related illness in small animals presenting to veterinary practices in the UK between 2013-2018..