Skip to main content

Research Repository

Advanced Search

Are Eimeria Genetically Diverse, and Does It Matter? (2017)
Journal Article
Clark, E. L., Tomley, F. M., & Blake, D. P. (2017). Are Eimeria Genetically Diverse, and Does It Matter?. Trends in Parasitology, 33(3), 231-241. https://doi.org/10.1016/j.pt.2016.08.007

Eimeria pose a risk to all livestock species as a cause of coccidiosis, reducing productivity and compromising animal welfare. Pressure to reduce drug use in the food chain makes the development of cost-effective vaccines against Eimeria essential. F... Read More about Are Eimeria Genetically Diverse, and Does It Matter?.

Population, genetic, and antigenic diversity of the apicomplexan Eimeria tenella and their relevance to vaccine development (2015)
Journal Article
Blake, D. P., Clark, E. L., Macdonald, S. E., Thenmozhi, V., Kundu, K., Garg, R., …Tomley, F. M. (2015). Population, genetic, and antigenic diversity of the apicomplexan Eimeria tenella and their relevance to vaccine development. https://doi.org/10.1073/pnas.1506468112

The phylum Apicomplexa includes serious pathogens of humans and animals. Understanding the distribution and population structure of these protozoan parasites is of fundamental importance to explain disease epidemiology and develop sustainable control... Read More about Population, genetic, and antigenic diversity of the apicomplexan Eimeria tenella and their relevance to vaccine development.

MORN1 has a conserved role in asexual and sexual development across the apicomplexa. Eukaryot Cell
Journal Article
Ferguson, D. J. P., Sahoo, N., Pinches, R. A., Bumstead, J. M., Tomley, F. M., & Gubbels, M. J. (in press). MORN1 has a conserved role in asexual and sexual development across the apicomplexa. Eukaryot Cell. https://doi.org/10.1128/EC.00021-08

The gene encoding the membrane occupation and recognition nexus protein MORN1 is conserved across the Apicomplexa. In Toxoplasma gondii, MORN1 is associated with the spindle poles, the anterior and posterior rings of the inner membrane complex (IMC).... Read More about MORN1 has a conserved role in asexual and sexual development across the apicomplexa. Eukaryot Cell.

Plasmodium male development gene-1 (mdv-1) is important for female sexual development and identifies a polarised plasma membrane during zygote development
Journal Article
Lal, K., Delves, M. J., Bromley, E., Wastling, J. M., Tomley, F. M., & Sinden, R. E. Plasmodium male development gene-1 (mdv-1) is important for female sexual development and identifies a polarised plasma membrane during zygote development. International Journal for Parasitology, 39(7), 755-61. https://doi.org/10.1016/j.ijpara.2008.11.008

Conservation of proteins involved in oocyst wall formation in Eimeria maxima, Eimeria tenella and Eimeria acervulina
Journal Article
Belli, S. I., Ferguson, D. J. P., Katrib, M., Slapetova, I., Mai, K., Slapeta, J., …Smith, N. C. (in press). Conservation of proteins involved in oocyst wall formation in Eimeria maxima, Eimeria tenella and Eimeria acervulina. International Journal for Parasitology, 39(10), 1063-70. https://doi.org/10.1016/j.ijpara.2009.05.004

Vaccination with proteins from gametocytes of Eimeria maxima protects chickens, via transfer of maternal antibodies, against infection with several species of Eimeria. Antibodies to E. maxima gametocyte proteins recognise proteins in the wall forming... Read More about Conservation of proteins involved in oocyst wall formation in Eimeria maxima, Eimeria tenella and Eimeria acervulina.