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Evaluation of the time-activity budgets of captive ducks (Anatidae) compared to wild counterparts (2022)
Journal Article
Rose, P., Roper, A., Banks, S., Giorgio, C., Timms, M., Vaughan, P., …O'Brien, M. (2022). Evaluation of the time-activity budgets of captive ducks (Anatidae) compared to wild counterparts. Applied Animal Behaviour Science, 251, https://doi.org/10.1016/j.applanim.2022.105626

Ducks are commonly housed in captive environments where their abilities for flight are constrained, either temporarily or permanently. The use of flight restraint in modern animal management is contentious and ethically questioned yet any associated... Read More about Evaluation of the time-activity budgets of captive ducks (Anatidae) compared to wild counterparts.

Characterization of Equine Chronic Tendon Lesions in Low- and High-Field Magnetic Resonance Imaging (2022)
Journal Article
Doll, C., von Pueckler, K., Offhaus, J., Berner, D., & Burk, J. (2022). Characterization of Equine Chronic Tendon Lesions in Low- and High-Field Magnetic Resonance Imaging. Veterinary Sciences, 9(6), https://doi.org/10.3390/vetsci9060297

In equine medicine, experience regarding MRI of chronic tendon lesions is limited, and evidence on the suitability of different sequences in 3 T high-field MRI is scarce. Therefore, macroscopically healthy and altered tendons were examined by histolo... Read More about Characterization of Equine Chronic Tendon Lesions in Low- and High-Field Magnetic Resonance Imaging.

Context Dependent Sulf1/Sulf2 Functional Divergence in Endothelial Cell Activity (2022)
Journal Article
Justo, T., Smart, N., & Dhoot, G. (2022). Context Dependent Sulf1/Sulf2 Functional Divergence in Endothelial Cell Activity. International Journal of Molecular Sciences, 23(7), https://doi.org/10.3390/ijms23073769

Signalling activities are tightly regulated to control cellular responses. Heparan sulfate proteoglycans (HSPGs) at the cell membrane and extracellular matrix regulate ligand availability and interaction with a range of key receptors. SULF1 and SULF2... Read More about Context Dependent Sulf1/Sulf2 Functional Divergence in Endothelial Cell Activity.

Overcoming temporal dispersion for measurement of activity-related impedance changes in unmyelinated nerves (2022)
Journal Article
Tarotin, I., Mastitskaya, S., Ravagli, E., Perkins, J., Holder, D., & Aristovich, K. (2022). Overcoming temporal dispersion for measurement of activity-related impedance changes in unmyelinated nerves. Journal of Neural Engineering, 19(2), https://doi.org/10.1088/1741-2552/ac669a

Objective. Fast neural electrical impedance tomography is an imaging technique that has been successful in visualising electrically evoked activity of myelinated fibres in peripheral nerves by measurement of the impedance changes (dZ) accompanying ex... Read More about Overcoming temporal dispersion for measurement of activity-related impedance changes in unmyelinated nerves.

Misconceptions of Antibiotics as a Potential Explanation for Their Misuse. A Survey of the General Public in a Rural and Urban Community in Sri Lanka (2022)
Journal Article
Gunasekera, Y., Kinnison, T., Kottawatta, S., Silva-Fletcher, A., & Kalupahana, R. (2022). Misconceptions of Antibiotics as a Potential Explanation for Their Misuse. A Survey of the General Public in a Rural and Urban Community in Sri Lanka. Antibiotics, 11(4), https://doi.org/10.3390/antibiotics11040454

Reducing the growth of antimicrobial resistance (AMR) through public understanding is a goal of the World Health Organization. It is especially important in countries where antibiotics are widely available for common ailments without prescription. Th... Read More about Misconceptions of Antibiotics as a Potential Explanation for Their Misuse. A Survey of the General Public in a Rural and Urban Community in Sri Lanka.

How much is that doodle in the window? Exploring motivations and behaviours of UK owners acquiring designer crossbreed dogs (2019-2020) (2022)
Journal Article
Burnett, E., Brand, C. L., O’Neill, D. G., Pegram, C. L., Belshaw, Z., Stevens, K. B., & Packer, R. M. A. (2022). How much is that doodle in the window? Exploring motivations and behaviours of UK owners acquiring designer crossbreed dogs (2019-2020). Canine Medicine and Genetics, 9(1), https://doi.org/10.1186/s40575-022-00120-x

Demand for intentional crosses of purebred dog breeds, often labelled ‘designer crossbreeds’ (e.g., Labrador Retriever X Poodle, the ‘Labradoodle’), has recently increased in the UK. This study aimed to explore this phenomenon by comparing pre-purcha... Read More about How much is that doodle in the window? Exploring motivations and behaviours of UK owners acquiring designer crossbreed dogs (2019-2020).

Research Note: MHCY haplotype impacts Campylobacter jejuni colonization in a backcross [(Line 6(1) x Line N) x Line N] population (2022)
Journal Article
Zhang, J., Goto, R., Psifidi, A., Stevens, M., Taylor, R., & Miller, M. (2022). Research Note: MHCY haplotype impacts Campylobacter jejuni colonization in a backcross [(Line 6(1) x Line N) x Line N] population. Poultry Science, 101(3), https://doi.org/10.1016/j.psj.2021.101654

MHCY is a candidate region for influencing immune responses in chickens. MHCY contains multiple specialized, polymorphic MHC class I loci along with loci belonging to 4 additional gene families. In this study, MHCY haplotypes were tested for associat... Read More about Research Note: MHCY haplotype impacts Campylobacter jejuni colonization in a backcross [(Line 6(1) x Line N) x Line N] population.

Demographic patterns of human antibody levels to Simulium damnosum s.l. saliva in onchocerciasis-endemic areas: An indicator of exposure to vector bites (2022)
Journal Article
Willen, L., Milton, P., Hamley, J., Walker, M., Osei-Atweneboana, M., Volf, P., …Courtenay, O. (2022). Demographic patterns of human antibody levels to Simulium damnosum s.l. saliva in onchocerciasis-endemic areas: An indicator of exposure to vector bites. PLoS Neglected Tropical Diseases, 16(1), https://doi.org/10.1371/journal.pntd.0010108

BackgroundIn onchocerciasis endemic areas in Africa, heterogenous biting rates by blackfly vectors on humans are assumed to partially explain age- and sex-dependent infection patterns with Onchocerca volvulus. To underpin these assumptions and furthe... Read More about Demographic patterns of human antibody levels to Simulium damnosum s.l. saliva in onchocerciasis-endemic areas: An indicator of exposure to vector bites.

A cluster-randomised, non-inferiority trial of the impact of a two-dose compared to three-dose schedule of pneumococcal conjugate vaccination in rural Gambia: the PVS trial (2022)
Journal Article
Mackenzie, G., Osei, I., Salaudeen, R., Hossain, I., Young, B., Secka, O., …Greenwood, B. (2022). A cluster-randomised, non-inferiority trial of the impact of a two-dose compared to three-dose schedule of pneumococcal conjugate vaccination in rural Gambia: the PVS trial. Trials, 23(1), https://doi.org/10.1186/s13063-021-05964-5

Background: Pneumococcal conjugate vaccines (PCV) effectively prevent pneumococcal disease but the global impact of pneumococcal vaccination is hampered by the cost of PCV. The relevance and feasibility of trials of reduced dose schedules is greatest... Read More about A cluster-randomised, non-inferiority trial of the impact of a two-dose compared to three-dose schedule of pneumococcal conjugate vaccination in rural Gambia: the PVS trial.

Regional variations in discrete collagen fibre mechanics within intact intervertebral disc resolved using synchrotron computed tomography and digital volume correlation (2022)
Journal Article
Disney, C., Mo, J., Eckersley, A., Bodey, A., Hoyland, J., Sherratt, M., …Bay, B. (2022). Regional variations in discrete collagen fibre mechanics within intact intervertebral disc resolved using synchrotron computed tomography and digital volume correlation. Acta Biomaterialia, 138, 361-374. https://doi.org/10.1016/j.actbio.2021.10.012

Many soft tissues, such as the intervertebral disc (IVD), have a hierarchical fibrous composite structure which suffers from regional damage. We hypothesise that these tissue regions have distinct, inherent fibre structure and structural response upo... Read More about Regional variations in discrete collagen fibre mechanics within intact intervertebral disc resolved using synchrotron computed tomography and digital volume correlation.

Use of multivariate analysis to evaluate antigenic relationships between US BVDV vaccine strains and non-US genetically divergent isolates (2022)
Journal Article
Mosena, A., Falkenberg, S., Ma, H., Casas, E., Dassanayake, R., Booth, R., …Neill, J. (2022). Use of multivariate analysis to evaluate antigenic relationships between US BVDV vaccine strains and non-US genetically divergent isolates. Journal of Virological Methods, 299, https://doi.org/10.1016/j.jviromet.2021.114328

Bovine viral diarrhea virus (BVDV) comprises two species, BVDV-1 and BVDV-2. But given the genetic diversity among pestiviruses, at least 22 subgenotypes are described for BVDV-1 and 3-4 for BVDV-2. Genetic characterization is generally accomplished... Read More about Use of multivariate analysis to evaluate antigenic relationships between US BVDV vaccine strains and non-US genetically divergent isolates.

Who's Getting a Head Start? Mesocephalic Dogs in Still Images Are Attributed More Positively Valenced Emotions Than Dogs of Other Cephalic Index Groups (2022)
Journal Article
Brincat, B., McGreevy, P., Bowell, V., & Packer, R. (2022). Who's Getting a Head Start? Mesocephalic Dogs in Still Images Are Attributed More Positively Valenced Emotions Than Dogs of Other Cephalic Index Groups. Animals, 12(1), https://doi.org/10.3390/ani12010049

Simple Summary Elements of a dog's appearance in still images affect how positively human observers interpret that individual's personality. Given that this may influence caregiving and other aspects of dog ownership, it is important to examine this... Read More about Who's Getting a Head Start? Mesocephalic Dogs in Still Images Are Attributed More Positively Valenced Emotions Than Dogs of Other Cephalic Index Groups.

Nfkb2 deficiency and its impact on plasma cells and immunoglobulin expression in murine small intestinal mucosa (2022)
Journal Article
Papoutsopoulou, S., Tang, J., Elramli, A. H., Williams, J. M., Gupta, N., Ikuomola, F. I., …Pritchard, D. M. (2022). Nfkb2 deficiency and its impact on plasma cells and immunoglobulin expression in murine small intestinal mucosa. American Journal of Physiology - Gastrointestinal and Liver Physiology, 323(4), G306-G317. https://doi.org/10.1152/ajpgi.00037.2022

Background & aims: The alternative (non-canonical) nuclear factor-kB (NF-kB) signalling pathway predominantly regulates the function of the p52/RelB heterodimer. Germline Nfkb2 deficiency in mice leads to loss of p100/p52 protein and offers protectio... Read More about Nfkb2 deficiency and its impact on plasma cells and immunoglobulin expression in murine small intestinal mucosa.

Dairy vs. beef production – expert views on welfare of cattle in common food production systems (2022)
Journal Article
Mandel, R., Bracke, M., Nicol, C., Webster, J., & Gygax, L. (2022). Dairy vs. beef production – expert views on welfare of cattle in common food production systems. animal, https://doi.org/10.1016/j.animal.2022.100622

Consumers’ views and concerns about the welfare of farm animals may play an important role in their decision to consume dairy, meat and/or plants as their primary protein source. As animals are killed prematurely in both dairy and beef industries, it... Read More about Dairy vs. beef production – expert views on welfare of cattle in common food production systems.

Galleria mellonella as an infection model for the virulent Mycobacterium tuberculosis H37Rv (2022)
Journal Article
Asai, M., Li, Y., Spiropoulos, J., Cooley, W., Everest, D. J., Kendall, S., …Newton, S. M. (2022). Galleria mellonella as an infection model for the virulent Mycobacterium tuberculosis H37Rv. Virulence, https://doi.org/10.1080/21505594.2022.2119657

Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), is a leading cause of infectious disease mortality. Animal infection models have contributed substantially to our understanding of TB, yet their biological and non-biological limitation... Read More about Galleria mellonella as an infection model for the virulent Mycobacterium tuberculosis H37Rv.

Modelling livestock test-and-treat: A novel One Health strategy to control schistosomiasis and mitigate drug resistance (2022)
Journal Article
Díaz, A. V., Lambert, S., Neves, M. I., Borlase, A., Léger, E., Diouf, N. D., …Walker, M. (2022). Modelling livestock test-and-treat: A novel One Health strategy to control schistosomiasis and mitigate drug resistance. Frontiers in Tropical Diseases, 3, 1-12. https://doi.org/10.3389/fitd.2022.893066

Schistosomiasis, a neglected tropical disease, is a widespread chronic helminthiasis reported in 78 countries, predominantly those within sub-Saharan Africa, as well as Latin America, Asia, and most recently, even Europe. Species of the causative blo... Read More about Modelling livestock test-and-treat: A novel One Health strategy to control schistosomiasis and mitigate drug resistance.

Investigation of in vitro susceptibility and resistance mechanisms in skin pathogens: perspectives for fluoroquinolone therapy in canine pyoderma (2022)
Journal Article
Azzariti, S., Bond, R., Loeffler, A., Zendri, F., Timofte, D., Chang, Y., & Pelligand, L. (2022). Investigation of in vitro susceptibility and resistance mechanisms in skin pathogens: perspectives for fluoroquinolone therapy in canine pyoderma. Antibiotics, https://doi.org/10.3390/antibiotics11091204

Fluoroquinolones (FQ) are commonly used in dogs with bacterial skin infections. Their use as first choice, along with the increased incidence of FQ-resistance, represents a risk to animal and public health. Our study determined minimum inhibitory (M... Read More about Investigation of in vitro susceptibility and resistance mechanisms in skin pathogens: perspectives for fluoroquinolone therapy in canine pyoderma.