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Equine Pituitary Pars Intermedia Dysfunction (2025)
Journal Article
Menzies-Gow, N. (2025). Equine Pituitary Pars Intermedia Dysfunction. Veterinary Sciences, 12, https://doi.org/10.3390/vetsci12080780

Simple Summary Pituitary pars intermedia dysfunction (PPID) is a common disease in older equines that is associated with loss of the dopaminergic inhibitory input from the hypothalamus to the pars intermedia region of the pituitary gland. This result... Read More about Equine Pituitary Pars Intermedia Dysfunction.

Yorkshire Terriers under primary veterinary care in the UK – demography and disorders (2025)
Journal Article
O'Neill, D., Witkowska, S. D., Brodbelt, D. C., Church, D. B., & Engdahl, K. S. (2025). Yorkshire Terriers under primary veterinary care in the UK – demography and disorders. Herpetological Conservation and Biology, 12(1), 6. https://doi.org/10.1186/s40575-025-00145-y

Background
The Yorkshire Terrier is a long-established and commonly owned dog breed. This study aimed to explore anonymised primary-care veterinary clinical data from the VetCompass Programme to characterise the demography, common disorders and long... Read More about Yorkshire Terriers under primary veterinary care in the UK – demography and disorders.

Florfenicol Sustained-Release formulation does not promote resistance emergence in non-target bacteria: hollow-fibre infection studies with pig pathogens and commensals (2025)
Journal Article
Mead, A., Azzariti, S., Hughes, A., Toutain, P.-L., & Pelligand, L. (2025). Florfenicol Sustained-Release formulation does not promote resistance emergence in non-target bacteria: hollow-fibre infection studies with pig pathogens and commensals. Journal of Applied Microbiology, 136(8), https://doi.org/10.1093/jambio/lxaf200

Aims
This study assessed the pharmacodynamic (PD) efficacy and resistance selection risk of a novel sustained-release (SR) florfenicol formulation versus a conventional two-dose regimen for treating swine respiratory pathogens, with particular atten... Read More about Florfenicol Sustained-Release formulation does not promote resistance emergence in non-target bacteria: hollow-fibre infection studies with pig pathogens and commensals.

Epidemiology and clinical management of nail clipping in dogs under UK primary veterinary care (2025)
Journal Article
O'Neill, D., Ahmed, L. . A., Somarriba, M., Brodbelt, D. . C., & Church, D. . B. (2025). Epidemiology and clinical management of nail clipping in dogs under UK primary veterinary care. Herpetological Conservation and Biology, https://doi.org/10.1111/jsap.70002

Objectives This study aimed to report the frequency, risk factors and clinical management of nail clipping in dogs under primary veterinary care across the United Kingdom during 2019 within the VetCompass Programme. Materials and Methods From a popul... Read More about Epidemiology and clinical management of nail clipping in dogs under UK primary veterinary care.

Optimizing ISO standard microbiological techniques for isolating Campylobacter from poultry samples amidst challenges from extended spectrum beta lactamase producing Escherichia coli (2025)
Journal Article
Ghosh, K., Logno, T. A., Das, T., Dhar, P. K., Blake, D., Fournie, G., Tomley, F., Stabler, R. A., Lehri, B., & Biswas, P. K. (2025). Optimizing ISO standard microbiological techniques for isolating Campylobacter from poultry samples amidst challenges from extended spectrum beta lactamase producing Escherichia coli. PLoS ONE, 20(7), Article e0327963. https://doi.org/10.1371/journal.pone.0327963

Welfare of American mink, red and Arctic foxes, raccoon dog and chinchilla kept for fur production (2025)
Journal Article
EFSA Panel on Animal Health and Welfare (AHAW), E., Nielsen, S. S., Álvarez, J., Boklund, A. E., Dippel, S., Dorea, F., Figuerola, J., Miranda Chueca, M. Á., Michel, V., Nannoni, E., Nonno, R., Riber, A. B., Stahl, K., Stegeman, J. A., Thulke, H., Tuyttens, F., Winckler, C., Díez‐León, M., Edwards, S., Schwarzer, A., …Herskin, M. S. (2025). Welfare of American mink, red and Arctic foxes, raccoon dog and chinchilla kept for fur production. EFSA Journal, 23(7), https://doi.org/10.2903/j.efsa.2025.9519

Pathophysiology of penetrating captive-bolt stunning of horses (2025)
Journal Article
Fletcher, K., Benedetti, B., Limon, G., Grist, A., Padalino, B., Hernández-Gil, M., & Gibson, T. (2025). Pathophysiology of penetrating captive-bolt stunning of horses. Animal Welfare Journal, 34, https://doi.org/10.1017/awf.2025.10025

There has been limited research into the effectiveness of penetrating captive bolt (PCB) for stunning horses (Equus caballus) at slaughter. This study observed 100 horses at a commercial abattoir in Mexico, stunned using pneumatic PCB. Animals were a... Read More about Pathophysiology of penetrating captive-bolt stunning of horses.

Long bone microanatomy in elephants: microstructural insights into gigantic beasts (2025)
Journal Article
Hutchinson, J., Bader, C., Gilardet, R., Rinder, N., Herridge, V., & Houssaye, A. (2025). Long bone microanatomy in elephants: microstructural insights into gigantic beasts. Zoological Journal of the Linnean Society, 204(3), https://doi.org/10.1093/zoolinnean/zlaf008

One of the greatest challenges of terrestrial locomotion is gravity. The morphological adaptive features of the limb long bones of extant elephants, the heaviest living terrestrial animals, have previously been highlighted; however, their bone microa... Read More about Long bone microanatomy in elephants: microstructural insights into gigantic beasts.

How femoral morphology informs our understanding of the evolution of ornithopod locomotion and body size (2025)
Journal Article
Pintore, R., Houssaye, A., & Hutchinson, J. (2025). How femoral morphology informs our understanding of the evolution of ornithopod locomotion and body size. Palaeontology, 68(4), https://doi.org/10.1111/pala.70016

Ornithopoda is one of the three main ornithischian dinosaur clades in which secondary quadrupedality is represented. However, when it evolved from obligate bipedality remains controversial. Indeed, the ability to alternate between the two habits was... Read More about How femoral morphology informs our understanding of the evolution of ornithopod locomotion and body size.

Evaluation of tumour biomarkers associated with invasion, metastasis and immune escape in cats with exocrine pancreatic carcinoma (2025)
Journal Article
Guillén, A., Kropp, K., Rogato, F., Yale, A. D., Hetesy, G., Béguin, J., Erles, K., Priestnall, S. L., Reyes-Gomez, E., & Hardas, A. (2025). Evaluation of tumour biomarkers associated with invasion, metastasis and immune escape in cats with exocrine pancreatic carcinoma. Journal of Comparative Pathology, 220, 47-55. https://doi.org/10.1016/j.jcpa.2025.05.009

In humans and cats, pancreatic carcinoma (PC) arising from the exocrine pancreas is considered an aggressive cancer associated with a poor prognosis due to its high metastatic rate. The aim of this retrospective multi-institutional study was to inves... Read More about Evaluation of tumour biomarkers associated with invasion, metastasis and immune escape in cats with exocrine pancreatic carcinoma.

Glutaminase as a metabolic target of choice to counter acquired resistance to Palbociclib by colorectal cancer cells (2025)
Journal Article
Tarrado-Castellarnau, M., Foguet, C., Tarragó-Celada, J., Palobart, M., Hernández-Carro, C., Perarnau, J., Zodda, E., Polat, I., Marin, S., Suarez-Bonnet, A., Lozano, J., Yuneva, M., Thomson, T., & Cascante, M. (2025). Glutaminase as a metabolic target of choice to counter acquired resistance to Palbociclib by colorectal cancer cells. Oncogene, https://doi.org/10.1038/s41388-025-03495-w

Several mechanisms of resistance of cancer cells to cyclin-dependent kinase inhibitors (CDKi) have been identified, including the upregulation of metabolic regulators such as glutaminase. However, whether such resistance mechanisms represent optimal... Read More about Glutaminase as a metabolic target of choice to counter acquired resistance to Palbociclib by colorectal cancer cells.

Uncovering the molecular signature of feline diffuse iris melanoma through transcriptomic analysis of disease severity (2025)
Journal Article
Kayes, D., Blacklock, B., McGeachan, R., Scurrell, E., Donnelly, K., Murphy, L., Fawkes, A., Clark, R., Meynert, A., Becher, H., Pittaway, R., Fricker, G., Pont, R., Suárez-Bonnet, A., & Blacklock, K. (2025). Uncovering the molecular signature of feline diffuse iris melanoma through transcriptomic analysis of disease severity. Scientific Reports, 15(1), https://doi.org/10.1038/s41598-025-09632-5

Feline diffuse iris melanoma (FDIM) is the most common primary ocular tumour in cats, with metastatic disease occurring in 19-63% of patients. Greater intraocular invasion correlates with increased mortality. No effective therapeutics exist for metas... Read More about Uncovering the molecular signature of feline diffuse iris melanoma through transcriptomic analysis of disease severity.

Injuries to the superficial digital flexor tendon branches: Clinical presentation, diagnostic features and outcome (2025)
Journal Article
Spiesshofer, P., O'Hara, V., Garrett, K., & Smith, R. (2025). Injuries to the superficial digital flexor tendon branches: Clinical presentation, diagnostic features and outcome. Equine Veterinary Education, https://doi.org/10.1111/eve.14205

BackgroundInjury of the superficial digital flexor tendon (SDFT) branch is uncommon and the response to different treatments has not been reported.ObjectivesThe aim of this study was to describe the clinical presentation, diagnostic features, treatme... Read More about Injuries to the superficial digital flexor tendon branches: Clinical presentation, diagnostic features and outcome.

Study of dense granule proteins in Eimeria spp. identifies a limited repertoire with potential as vaccine candidates (2025)
Journal Article
Sanchez-Arsuaga, G., Blake, D., Tomley, F., & Marugan-Hernandez, V. (2025). Study of dense granule proteins in Eimeria spp. identifies a limited repertoire with potential as vaccine candidates. Frontiers in Immunology, 16, https://doi.org/10.3389/fimmu.2025.1605984

Eimeria species are obligate intracellular parasites that usually replicate in intestinal cells and can cause the disease coccidiosis. Coccidiosis of livestock and poultry incurs significant production losses and compromises animal welfare, with the... Read More about Study of dense granule proteins in Eimeria spp. identifies a limited repertoire with potential as vaccine candidates.

Desmin disorganisation: A key feature in feline hypertrophic cardiomyopathy (2025)
Journal Article
Connolly, D., Chen, W.-C., Lawson, C., Wilkie, L., Dobromylsky, M., Fuentes, V. L., Holt, M. R., & Ehler, E. (2025). Desmin disorganisation: A key feature in feline hypertrophic cardiomyopathy. Basic Research in Cardiology, https://doi.org/10.1371/journal.pone.0327850

https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0327850&?utm_id=plos111&utm_source=internal&utm_medium=email&utm_campaign=author

Hypertrophic cardiomyopathy is usually characterised histologically by increased ventricular wall t... Read More about Desmin disorganisation: A key feature in feline hypertrophic cardiomyopathy.

Occult tethered cord syndrome: insights into clinical and MRI features, prognostic factors, and treatment outcomes in 30 dogs with confirmed or presumptive diagnosis (2025)
Journal Article
Romero, J., De Decker, S., Santifort, K., Gutierrez-Quintana, R., Ortega, M., Uriarte, A., Mojarradi, A., van Koulil, Q., Douralidou, D., Espadas, I., Benito, M., Anselmi, C., Dye, C., Alvarez, P., Minguez, J., Crawford, A., & Posporis, C. (2025). Occult tethered cord syndrome: insights into clinical and MRI features, prognostic factors, and treatment outcomes in 30 dogs with confirmed or presumptive diagnosis. Frontiers in Veterinary Science, 12, https://doi.org/10.3389/fvets.2025.1588538

Occult tethered cord syndrome (OTCS) is poorly documented in dogs. This retrospective multicenter study evaluated the clinical presentation, MRI findings, treatment outcomes, and prognostic factors in 30 dogs diagnosed with OTCS managed surgically (n... Read More about Occult tethered cord syndrome: insights into clinical and MRI features, prognostic factors, and treatment outcomes in 30 dogs with confirmed or presumptive diagnosis.

Unwelcome neighbours: Tracking the transmission of Streptococcus equi in the United Kingdom horse population (2025)
Journal Article
McGlennon, A., Verheyen, K., Newton, J., van Tonder, A., Wilson, H., Parkhill, J., de Brauwere, N., Frosth, S., & Waller, A. (2025). Unwelcome neighbours: Tracking the transmission of Streptococcus equi in the United Kingdom horse population. Equine Veterinary Journal, https://doi.org/10.1111/evj.14558

Background: Strangles (Streptococcus equi infection) remains endemic in the UK, with similar to 300 laboratory diagnoses annually. Sub-clinically infected long-term carriers are considered a key driver of endemicity. Analysing genomes of circulating... Read More about Unwelcome neighbours: Tracking the transmission of Streptococcus equi in the United Kingdom horse population.