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All Outputs (10695)

Population pharmacokinetics modelling for clinical dose adjustment of carboplatin in dogs (2025)
Journal Article
Béguin, J., Mahfoudhi, S., Uzel, M., Rostang, A., Ibish, C., Ferran, A., Pelligand, L., Hulin, A., & Kohlhauer, M. (in press). Population pharmacokinetics modelling for clinical dose adjustment of carboplatin in dogs. BMC Veterinary Research, https://doi.org/10.1186/s12917-024-04404-1

Carboplatin is a human chemotherapeutic agent which is frequently used in dogs for the management of solid tumors. In human patient, its dosage is adjusted carefully, based on the creatinine clearance computation. In dogs however, the pharmacokinetic... Read More about Population pharmacokinetics modelling for clinical dose adjustment of carboplatin in dogs.

Animal welfare risks from commercial practices involving cephalopod molluscs and decapod crustaceans (2025)
Journal Article
Browning, H., Burn, C., Schnell, A., Crump, A., & Birch, J. (2025). Animal welfare risks from commercial practices involving cephalopod molluscs and decapod crustaceans. Animal Welfare Journal, https://doi.org/10.1017/awf.2025.25

There is increasing recognition that the welfare needs of cephalopod molluscs and decapod crustaceans are important. Current commercial practices involving these animals include a range of potential threats to their welfare, such as conditions of far... Read More about Animal welfare risks from commercial practices involving cephalopod molluscs and decapod crustaceans.

Pharmacokinetic–pharmacodynamic cutoff values for doxycycline in pigs to support the establishment of clinical breakpoints for antimicrobial susceptibility testing (2025)
Journal Article
Pelligand, L., Toutain, P.-L., Bouquet-Mélou, A., Ferran, A., Roques, B., del Castillo, J., Lees, P., Croubels, S., & Bousquet, E. (2025). Pharmacokinetic–pharmacodynamic cutoff values for doxycycline in pigs to support the establishment of clinical breakpoints for antimicrobial susceptibility testing. Journal of Veterinary Pharmacology and Therapeutics, https://doi.org/10.1111/jvp.13511

This meta-analysis provides a population model of doxycycline (DOXY) disposition in pigs for computation of PK/PD cutoff values corresponding to differing modalities of DOXY administration orally in pigs. This analysis enables establishment of specif... Read More about Pharmacokinetic–pharmacodynamic cutoff values for doxycycline in pigs to support the establishment of clinical breakpoints for antimicrobial susceptibility testing.

Porcupine inhibition is a promising pharmacological treatment for severe sclerosteosis pathologies (2025)
Journal Article
Dreyer, T., Keen, J., Wells, L., Hopkinson, M., Orriss, I., Holdsworth, G., Pitsillides, A., & Roberts, S. (2025). Porcupine inhibition is a promising pharmacological treatment for severe sclerosteosis pathologies. Bone Research, 13(1), https://doi.org/10.1038/s41413-025-00406-3

Sclerosteosis, an ultra-rare disorder characterised by high bone mass (HBM) and skeletal overgrowth, leads to facial paralysis, hearing loss and raised intracranial pressure, which is currently managed only through high-risk surgery. Sclerosteosis is... Read More about Porcupine inhibition is a promising pharmacological treatment for severe sclerosteosis pathologies.

Limited occurrence of Borrelia burgdorferi sensu lato in the European hedgehog (Erinaceus europaeus) and Ixodes hexagonus in Great Britain (2025)
Journal Article
Vecchiato, M., Lawson, B., Seilern-Moy, K., White, M. L., Jones, N., Brown, F., Yaffy, D., Medlock, J. M., & Hansford, K. M. (2025). Limited occurrence of Borrelia burgdorferi sensu lato in the European hedgehog (Erinaceus europaeus) and Ixodes hexagonus in Great Britain. Ticks and Tick-borne Diseases, 16(3), 102475. https://doi.org/10.1016/j.ttbdis.2025.102475

Dental disease in rabbits under UK primary veterinary care: Clinical management and associated welfare impacts (2025)
Journal Article
Jackson, M., O'Neill, D., Hedley, J., Brodbelt, D., & Burn, C. (2025). Dental disease in rabbits under UK primary veterinary care: Clinical management and associated welfare impacts. Veterinary Record, https://doi.org/10.1002/vetr.5326

Background: Dental disease is painful and highly prevalent in companion rabbits, but current veterinary management techniques and clinical welfare implications are little described.
Methods: Anonymised VetCompass clinical records were manually revi... Read More about Dental disease in rabbits under UK primary veterinary care: Clinical management and associated welfare impacts.

Rabbit dental abnormalities: Investigation of conformational risk factors in a pedigree rabbit population (2025)
Journal Article
Jackson, M., Betts, M., Hedley, J., & Burn, C. (2025). Rabbit dental abnormalities: Investigation of conformational risk factors in a pedigree rabbit population. Animals, https://doi.org/10.3390/ani15070980

Lop-eared and brachycephalic conformations have inconsistently been associated with dental abnormalities in pet and rescue rabbit populations. We investigated conformational risk factors for dental abnormalities in a pedigree population where conform... Read More about Rabbit dental abnormalities: Investigation of conformational risk factors in a pedigree rabbit population.

Unravelling theory in choice analysis: do consumers fill in the blanks? (2025)
Journal Article
Kristina Edenbrandt, A., & Haesler, B. (2025). Unravelling theory in choice analysis: do consumers fill in the blanks?. European Review of Agricultural Economics, https://doi.org/10.1093/erae/jbaf009

Unravelling theory postulates that consumers assume products without quality information are of the lowest quality. In a discrete choice experiment (DCE) with 1987 respondents from the UK, we find evidence against this assumption. Affirmative disclos... Read More about Unravelling theory in choice analysis: do consumers fill in the blanks?.

Association of the TTN, PDK4, and RNF207 mutations with dilated cardiomyopathy in Dobermanns from the United Kingdom (2025)
Journal Article
Dutton, L., Crossland, A., Dukes-McEwan, J., & Connolly, D. (2025). Association of the TTN, PDK4, and RNF207 mutations with dilated cardiomyopathy in Dobermanns from the United Kingdom. PLoS ONE, 2025 Mar 13;20(3):e0319932, https://doi.org/10.1371/journal.pone.0319932

A missense mutation in the titin gene (TTN) and a splice-site mutation in the pyruvate dehydrogenase kinase 4 gene (PDK4) have been associated with dilated cardiomyopathy (DCM) in Dobermanns from the United States. Additionally, a missense mutation i... Read More about Association of the TTN, PDK4, and RNF207 mutations with dilated cardiomyopathy in Dobermanns from the United Kingdom.

Analysis of Cattle Foot Lesions Recorded at Trimming in the Southwest of England (2025)
Journal Article
Britten, N., Blackie, N., Reader, J., Booth, R. E., & Mahendran, S. A. (in press). Analysis of Cattle Foot Lesions Recorded at Trimming in the Southwest of England. Animals, 15(6), 829. https://doi.org/10.3390/ani15060829

Background: The UK has a high incidence of lameness in cattle, which is costly in terms of economics and welfare. Most causes of bovine lameness originate in the foot but there are several different conditions causing lameness. Quantifying the relati... Read More about Analysis of Cattle Foot Lesions Recorded at Trimming in the Southwest of England.

Ultrasonographic features of gastrointestinal ulcerations in cats (2025)
Journal Article
Bach, A., de la Serna, B., Maddox, T., & Weston, P. (2025). Ultrasonographic features of gastrointestinal ulcerations in cats. Veterinary Record, https://doi.org/10.1002/vetr.5222

Background: Gastrointestinal ulceration in cats can be life threatening due to the risk of perforation and septic peritonitis. However, the ultrasound findings associated with this condition and their diagnostic sensitivities have not been described.... Read More about Ultrasonographic features of gastrointestinal ulcerations in cats.

Erreurs en anesthésie : enquête et analyse de pratique un jour au bloc opératoire en France (2025)
Journal Article
Fuzier, R., Bordes, J., Basquin, C., Bordes-Demolis, M., Bourgain, J.-L., Campion, S., Fletcher, D., Morau, E., Pelieu, I., Pelligand, L., San Miguel, A., Soufir, L., Untereiner, O., Vacheron, C.-H., Blanié, A., & Picard, J. (online). Erreurs en anesthésie : enquête et analyse de pratique un jour au bloc opératoire en France. Anesthésie & Réanimation, https://doi.org/10.1016/j.anrea.2024.11.003

Severe periodontal disease in a geriatric southern white rhinoceros (Ceratotherium simum simum) (2025)
Journal Article
Wrigglesworth, E., Dodds, J., Morgan, R., Milnes, E., & Spiro, S. (2025). Severe periodontal disease in a geriatric southern white rhinoceros (Ceratotherium simum simum). Vet Record Case Reports, https://doi.org/10.1002/vrc2.70009

A geriatric southern white rhinoceros (Ceratotherium simum simum) held at a zoological institution was euthanased following persistent dysmastication and decreasing body condition. A postmortem examination revealed marked calculi on the surfaces of t... Read More about Severe periodontal disease in a geriatric southern white rhinoceros (Ceratotherium simum simum).

Computed tomographic appearance of gastropexy sites in dogs (2025)
Journal Article
Einwaller, J., Llabres-Diaz, F., Jones, C., & Caine, A. (2025). Computed tomographic appearance of gastropexy sites in dogs. Journal of Small Animal Practice, https://doi.org/10.1111/jsap.13842

Objectives: To describe the computed tomography appearance of gastropexy sites and report their anatomical and suspected functional abnormalities. Materials and methods: Medical records of dogs with prior gastropexy undergoing abdominal computed tomo... Read More about Computed tomographic appearance of gastropexy sites in dogs.