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The cholinergic anti-inflammatory pathway inhibits inflammation without lymphocyte relay (2023)
Journal Article
Simon, T., Kirk, J., Dolezalova, N., Guyot, M., Panzolini, C., Bondue, A., …Blancou, P. (2023). The cholinergic anti-inflammatory pathway inhibits inflammation without lymphocyte relay. Frontiers in Neuroscience, 17, https://doi.org/10.3389/fnins.2023.1125492

The magnitude of innate inflammatory immune responses is dependent on interactions between peripheral neural and immune cells. In particular, a cholinergic anti-inflammatory pathway (CAP) has been identified in the spleen whereby noradrenaline (NA) r... Read More about The cholinergic anti-inflammatory pathway inhibits inflammation without lymphocyte relay.

Review: The challenge to integrate animal welfare indicators into the Life Cycle Assessment (2023)
Journal Article
Lanzoni, L., Whatford, L., Atzori, A., Chincarini, M., Giammarco, M., Fusaro, I., & Vignola, G. (2023). Review: The challenge to integrate animal welfare indicators into the Life Cycle Assessment. animal, 17(5), https://doi.org/10.1016/j.animal.2023.100794

The transition to a more sustainable livestock sector represents one of the major challenges of our time. Life Cycle Assessment (LCA) is recognised as the gold standard methodology for assessing the environmental impact of farming systems. Simultaneo... Read More about Review: The challenge to integrate animal welfare indicators into the Life Cycle Assessment.

Dynamics of hinged wings in strong upward gusts (2023)
Journal Article
Stevenson, J., Cheney, J., Usherwood, J., Bomphrey, R., & Windsor, S. (2023). Dynamics of hinged wings in strong upward gusts. Royal Society Open Science, 10(5), https://doi.org/10.1098/rsos.221607

A bird's wings are articulated to its body via highly mobile shoulder joints. The joints confer an impressive range of motion, enabling the wings to make broad, sweeping movements that can modulate quite dramatically the production of aerodynamic loa... Read More about Dynamics of hinged wings in strong upward gusts.

Locomotor, ecological and phylogenetic drivers of skeletal proportions in frogs (2023)
Journal Article
Leavey, A., Ruta, M., Richards, C., & Porro, L. (2023). Locomotor, ecological and phylogenetic drivers of skeletal proportions in frogs. Journal of Anatomy, https://doi.org/10.1111/joa.13886

Frogs exhibit complex anatomical features of the pelvis, limbs and spine, long assumed to represent specialisations for jumping. Yet frogs employ a wide range of locomotor modes, with several taxa featuring primary locomotor modes other than jumping.... Read More about Locomotor, ecological and phylogenetic drivers of skeletal proportions in frogs.

Determining the prevalence and risk factors for positive bacterial culture in canine discospondylitis: 120 cases (2023)
Journal Article
Pilkington, E., Goncalves, R., Henze, L., Grapes, N., Volk, H., & De Decker, S. (2023). Determining the prevalence and risk factors for positive bacterial culture in canine discospondylitis: 120 cases. Veterinary Record, https://doi.org/10.1002/vetr.3053

BackgroundIdentification of the aetiologic agent in canine discospondylitis is infrequent; and risk factors for a positive bacterial culture have not previously been reported. MethodsMedical records at three institutions were searched to identify cli... Read More about Determining the prevalence and risk factors for positive bacterial culture in canine discospondylitis: 120 cases.

Spinal epidural empyema in a colobus monkey (2023)
Journal Article
Cehrs, E., & Beltran, E. (2023). Spinal epidural empyema in a colobus monkey. Vet Record Case Reports, https://doi.org/10.1002/vrc2.656

A 10-year-old, male colobus monkey presented with a kyphotic appearance. Lumbar spinal pain was suspected, and the colobus was started on a course of meloxicam. With no improvement noted, it was sedated for examination. Haematology revealed a neutrop... Read More about Spinal epidural empyema in a colobus monkey.

Comparison of radiography and CT for the evaluation of third carpal bone slab fractures in Thoroughbred racehorses (2023)
Journal Article
Dash, R., Minshall, G., & Wright, I. (2023). Comparison of radiography and CT for the evaluation of third carpal bone slab fractures in Thoroughbred racehorses. Veterinary Radiology and Ultrasound, https://doi.org/10.1111/vru.13255

Slab fractures of the third carpal bone (C3) are a common cause of lameness in Thoroughbred racehorses. Information on fracture morphology is commonly obtained from radiographs or CT. This retrospective, methods comparison aimed to explore the agreem... Read More about Comparison of radiography and CT for the evaluation of third carpal bone slab fractures in Thoroughbred racehorses.

Large granular lymphocyte lymphoma in 65 dogs (2005-2023) (2023)
Journal Article
Yale, A., Crawford, A., Gramer, I., Guillen, A., Desmas, I., & Holmes, E. (2023). Large granular lymphocyte lymphoma in 65 dogs (2005-2023). Veterinary and Comparative Oncology, https://doi.org/10.1111/vco.12959

Large granular lymphocyte lymphoma (LGLL) is a rare form of lymphoma in dogs. Limited information exists regarding presentation, treatment response, and outcome. The aim of this single-institute, retrospective study was to characterise clinical prese... Read More about Large granular lymphocyte lymphoma in 65 dogs (2005-2023).

Effects of individual and pair housing of calves on long term heifer production on a UK commercial dairy farm (2023)
Journal Article
Mahendran, S., Blackie, N., Wathes, D. C., & Booth, R. (in press). Effects of individual and pair housing of calves on long term heifer production on a UK commercial dairy farm. Animals, https://doi.org/10.3390/ani14010125

Pair housing of pre-weaning dairy calves has previously demonstrated positive impacts on their growth, health and behaviour, but longer-term effects on production are still relatively unknown. This study followed a cohort of 431 Holstein heifers recr... Read More about Effects of individual and pair housing of calves on long term heifer production on a UK commercial dairy farm.

Using a Whole Genome Co- expression Network to Inform the Functional Characterisation of Predicted Genomic Elements from Mycobacterium tuberculosis Transcriptomic Data (2023)
Journal Article
Stiens, J., Yi Tan, Y., Joyce, R., Arnvig, K. B., Kendall, S. L., & Nobeli, I. (in press). Using a Whole Genome Co- expression Network to Inform the Functional Characterisation of Predicted Genomic Elements from Mycobacterium tuberculosis Transcriptomic Data. Molecular Microbiology, https://doi.org/10.1111/mmi.15055

A whole genome co-expression network was created using Mycobacterium tuberculosis transcriptomic data from publicly available RNA-sequencing experiments covering a wide variety of experimental conditions. The network includes expressed regions with... Read More about Using a Whole Genome Co- expression Network to Inform the Functional Characterisation of Predicted Genomic Elements from Mycobacterium tuberculosis Transcriptomic Data.

CellShip: An Ambient Temperature Transport and Short-Term Storage Medium for Mammalian Cell Cultures (2023)
Journal Article
Buick, E., Mead, A., Alhubaysh, A., Bou Assi, P., Das, P., Dayus, J., …Farnaud, S. (in press). CellShip: An Ambient Temperature Transport and Short-Term Storage Medium for Mammalian Cell Cultures. Biopreservation and Biobanking, https://doi.org/10.1089/bio.2023.0100

Cell culture is a critical platform for numerous research and industrial processes. However, methods for transporting cells are largely limited to cryopreservation, which is logistically challenging, requires the use of potentially cytotoxic cryopres... Read More about CellShip: An Ambient Temperature Transport and Short-Term Storage Medium for Mammalian Cell Cultures.

Multi-ancestry genome-wide association meta-analysis of Parkinson's disease (2023)
Journal Article
Kim, J., Vitale, D., Otani, D., Lian, M., Heilbron, K., Aslibekyan, S., …Mata, I. (2023). Multi-ancestry genome-wide association meta-analysis of Parkinson's disease. Nature Genetics, https://doi.org/10.1038/s41588-023-01584-8

Although over 90 independent risk variants have been identified for Parkinson's disease using genome-wide association studies, most studies have been performed in just one population at a time. Here we performed a large-scale multi-ancestry meta-anal... Read More about Multi-ancestry genome-wide association meta-analysis of Parkinson's disease.

A Functional Single-Nucleotide Polymorphism Upstream of the Collagen Type III Gene Is Associated with Catastrophic Fracture Risk in Thoroughbred Horses (2023)
Journal Article
Lago, E. P., Baird, A., Blott, S. C., Mcphail, R. E., Ross, A. C., Durward-Akhurst, S. A., & Guest, D. J. (2023). A Functional Single-Nucleotide Polymorphism Upstream of the Collagen Type III Gene Is Associated with Catastrophic Fracture Risk in Thoroughbred Horses. Animals, 14(1), 116. https://doi.org/10.3390/ani14010116

Fractures caused by bone overloading are a leading cause of euthanasia in Thoroughbred racehorses. The risk of fatal fracture has been shown to be influenced by both environmental and genetic factors but, to date, no specific genetic mechanisms unde... Read More about A Functional Single-Nucleotide Polymorphism Upstream of the Collagen Type III Gene Is Associated with Catastrophic Fracture Risk in Thoroughbred Horses.

Diagnosis and surgical management of a type IV<i>b</i> dermoid sinus in a Cavalier King Charles Spaniel (2023)
Journal Article
Danciu, C., Briola, C., Volckaert, V., Mccready, D., Pittaway, R., & Fitzmaurice, S. (2023). Diagnosis and surgical management of a type IVb dermoid sinus in a Cavalier King Charles Spaniel. Vet Record Case Reports, https://doi.org/10.1002/vrc2.786

A 6-year-old, male, neutered Cavalier King Charles Spaniel dog was referred with a 4-year history of an intermittently draining fistula on the midline of the frontal bones of the skull. Magnetic resonance imaging and computed tomography scan of the h... Read More about Diagnosis and surgical management of a type IV<i>b</i> dermoid sinus in a Cavalier King Charles Spaniel.

Differential LRRK2 Signalling and Gene Expression in WT-LRRK2 and G2019S-LRRK2 Mouse Microglia Treated with Zymosan and MLi2 (2023)
Journal Article
Nazish, I., Mamais, A., Mallach, A., Bettencourt, C., Kaganovich, A., Warner, T., …Bandopadhyay, R. (2023). Differential LRRK2 Signalling and Gene Expression in WT-LRRK2 and G2019S-LRRK2 Mouse Microglia Treated with Zymosan and MLi2. Cells, 13(1), https://doi.org/10.3390/cells13010053

Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene cause autosomal dominant Parkinson's disease (PD), with the most common causative mutation being the LRRK2 p.G2019S within the kinase domain. LRRK2 protein is highly expressed in the human br... Read More about Differential LRRK2 Signalling and Gene Expression in WT-LRRK2 and G2019S-LRRK2 Mouse Microglia Treated with Zymosan and MLi2.

Post-Thaw Storage Temperature Influenced Boar Sperm Quality and Lifespan through Apoptosis and Lipid Peroxidation (2023)
Journal Article
Li, J., Li, J., Wang, S., Ju, H., Chen, S., Basioura, A., …Zhu, J. (2024). Post-Thaw Storage Temperature Influenced Boar Sperm Quality and Lifespan through Apoptosis and Lipid Peroxidation. Animals, 14(1), https://doi.org/10.3390/ani14010087

Simple Summary Frozen-thawed boar semen has not been widely used due to the deleterious effects of freezing on sperm quality and fertility. Extensive attempts have been made to improve post-thaw sperm quality because the short lifespan of frozen and... Read More about Post-Thaw Storage Temperature Influenced Boar Sperm Quality and Lifespan through Apoptosis and Lipid Peroxidation.

Associations between turn out practices and rates of musculoskeletal disease and injury in Thoroughbred foals and yearlings on stud farms in the United Kingdom. (2023)
Journal Article
Mouncey, R., Arango-Sabogal, J., de Mestre, A., & Verheyen, K. (in press). Associations between turn out practices and rates of musculoskeletal disease and injury in Thoroughbred foals and yearlings on stud farms in the United Kingdom. Equine Veterinary Journal, https://doi.org/10.1111/evj.14038

Abstract
Background: Early-life locomotor activity during turn out may alter susceptibility to musculoskeletal disease and injury via modulation of behaviors and tissue development during growth.
Objectives: Investigate associations between turn o... Read More about Associations between turn out practices and rates of musculoskeletal disease and injury in Thoroughbred foals and yearlings on stud farms in the United Kingdom..

Thyme, Oregano, and Garlic Essential Oils and Their Main Active Compounds Influence <i>Eimeria tenella</i> Intracellular Development (2023)
Journal Article
Felici, M., Tugnoli, B., De Hoest-Thompson, C., Piva, A., Grilli, E., & Marugan-Hernandez, V. (2024). Thyme, Oregano, and Garlic Essential Oils and Their Main Active Compounds Influence Eimeria tenella Intracellular Development. Animals, 14(1), https://doi.org/10.3390/ani14010077

Coccidiosis poses a significant challenge in poultry production and is typically managed with ionophores and chemical anticoccidials. However, the emergence of drug resistance and limitations on their use have encouraged the exploration of alternativ... Read More about Thyme, Oregano, and Garlic Essential Oils and Their Main Active Compounds Influence <i>Eimeria tenella</i> Intracellular Development.