Skip to main content

Research Repository

Advanced Search

All Outputs (10661)

Population pharmacokinetics modelling for clinical dose adjustment of carboplatin in dogs (2025)
Journal Article
Béguin, J., Mahfoudhi, S., Uzel, M., Rostang, A., Ibish, C., Ferran, A., Pelligand, L., Hulin, A., & Kohlhauer, M. (in press). Population pharmacokinetics modelling for clinical dose adjustment of carboplatin in dogs. BMC Veterinary Research, https://doi.org/10.1186/s12917-024-04404-1

Carboplatin is a human chemotherapeutic agent which is frequently used in dogs for the management of solid tumors. In human patient, its dosage is adjusted carefully, based on the creatinine clearance computation. In dogs however, the pharmacokinetic... Read More about Population pharmacokinetics modelling for clinical dose adjustment of carboplatin in dogs.

Erreurs en anesthésie : enquête et analyse de pratique un jour au bloc opératoire en France (2025)
Journal Article
Fuzier, R., Bordes, J., Basquin, C., Bordes-Demolis, M., Bourgain, J.-L., Campion, S., Fletcher, D., Morau, E., Pelieu, I., Pelligand, L., San Miguel, A., Soufir, L., Untereiner, O., Vacheron, C.-H., Blanié, A., & Picard, J. (online). Erreurs en anesthésie : enquête et analyse de pratique un jour au bloc opératoire en France. Anesthésie & Réanimation, https://doi.org/10.1016/j.anrea.2024.11.003

Emergency management of the polytrauma patient (2025)
Journal Article
O'Byrne, E., & Cole, L. (2025). Emergency management of the polytrauma patient. In Practice, 47(2), 71-79. https://doi.org/10.1002/inpr.516

Background: Polytrauma is a commonly seen emergency in veterinary practice and is defined as two or more injuries involving multiple body parts or organ systems. One or more of these injuries may be life threatening and patients can rapidly deteriora... Read More about Emergency management of the polytrauma patient.

Cocaine Differentially Affects Mitochondrial Function Depending on Exposure Time (2025)
Journal Article
Wattad, S., Bryant, G., Shmuel, M., Smith, H. L., Yaka, R., & Thornton, C. (in press). Cocaine Differentially Affects Mitochondrial Function Depending on Exposure Time. International Journal of Molecular Sciences, 26(5), 2131. https://doi.org/10.3390/ijms26052131

Cocaine use is a rising global concern, and increased use is accompanied by
a significant increase in people entering treatment for the first time. However, there are
still no complete therapies, and preclinical tools are necessary to both understa... Read More about Cocaine Differentially Affects Mitochondrial Function Depending on Exposure Time.

Behavioural Engagement of Holstein Friesian Dairy Cattle with Different Mounting Techniques for Salt Licks as Environmental Enrichment (2025)
Journal Article
McLaughlin, D., & Blackie, N. (2025). Behavioural Engagement of Holstein Friesian Dairy Cattle with Different Mounting Techniques for Salt Licks as Environmental Enrichment. Animals, 15(5), 701. https://doi.org/10.3390/ani15050701

With increasing numbers of dairy farms adopting zero-grazing systems, there is a growing need for indoor environmental enrichment methods. Enrichment is necessary to meet industry requirements and fulfil behavioural motivations, such as oral manipula... Read More about Behavioural Engagement of Holstein Friesian Dairy Cattle with Different Mounting Techniques for Salt Licks as Environmental Enrichment.

Behavioural Indicators of Infectious Disease in Managed Animals (2025)
Journal Article
Nicol, C. (in press). Behavioural Indicators of Infectious Disease in Managed Animals. Applied Animal Behaviour Science, https://doi.org/10.1016/j.applanim.2025.106573

Identifying reliable and valid behavioural indicators of infection in managed animals is increasingly important as the risks of emergent diseases increase alongside concomitant concerns over pathogen resistance and the environmental and safety impact... Read More about Behavioural Indicators of Infectious Disease in Managed Animals.

Comparison of Survival After Treatment of Presumed Intracranial Meningioma by Radiotherapy or Surgery in 285 Dogs (2025)
Journal Article
Geiger, R., Mankin, J., Volk, H., de Decker, S., van Asselt, N., Randhawa, K., Ehling, T., Maitz, C., Naramor, A., Coates, J., Stalin, C., Johnstone, L., Morris, J., Plessas, I., Forward, A., Garosi, L., Scarpante, E., Cherubini, G., Harcourt-Brown, T., Carrera-Justiz, S., …Jeffery, N. (2025). Comparison of Survival After Treatment of Presumed Intracranial Meningioma by Radiotherapy or Surgery in 285 Dogs. Journal of Veterinary Internal Medicine, 39(2), https://doi.org/10.1111/jvim.70011

BackgroundThe comparative effectiveness of radiotherapy and surgery for treating intracranial meningioma is unknown.ObjectivesTo compare survival after treatment of suspected intracranial meningioma by either surgery or radiotherapy.AnimalsTwo hundre... Read More about Comparison of Survival After Treatment of Presumed Intracranial Meningioma by Radiotherapy or Surgery in 285 Dogs.

Distinctive seizure signature in the first video case-control study of a naturally-occurring feline autoimmune encephalitis model (2025)
Journal Article
Binks, S., Crawford, A., Ives, E., Davison, L., Fox, H., Fower, A., Kaczmarska, A., Woodhall, M., Waters, P., Handel, A., Irani, S., Quintana, R. G., Chowdhury, F., Eriksson, S., & Pakozdy, A. (2025). Distinctive seizure signature in the first video case-control study of a naturally-occurring feline autoimmune encephalitis model. Brain, Behavior, and Immunity, https://doi.org/10.1016/j.bbi.2025.02.018

Calculation of standard bodyweights for dogs, cats, rabbits, and guinea pigs (2025)
Journal Article
O'Neill, D., Becker, S. D., Frosini, S.-M., Stapleton, L. E., Hughes, D. M., & Brodbelt, D. C. (2025). Calculation of standard bodyweights for dogs, cats, rabbits, and guinea pigs. PLoS ONE, 20(2), e0318734. https://doi.org/10.1371/journal.pone.0318734

Standard bodyweights are an essential component of calculations that summarise many
population-level measures in companion animals, including the defined daily doses for
veterinary species (DDDVet) reporting antimicrobial usage. Standard species bo... Read More about Calculation of standard bodyweights for dogs, cats, rabbits, and guinea pigs.

Lasting lockdown love? Problem behaviour and pandemic and non-pandemic related risk factors influencing the owner-dog relationship in a UK cohort of dogs reaching early adulthood (2025)
Journal Article
Merritt, B. L., O’Neill, D. G., Brand, C. L., Belshaw, Z., Dale, F. C., Pegram, C. L., & Packer, R. M. A. (in press). Lasting lockdown love? Problem behaviour and pandemic and non-pandemic related risk factors influencing the owner-dog relationship in a UK cohort of dogs reaching early adulthood. PLoS ONE, 20(2), e0316166. https://doi.org/10.1371/journal.pone.0316166

The owner-dog relationship is a critical component of sustained dog ownership. Increased understanding of risk factors for weak owner-dog relationships can identify owner-dog dyads at higher risk of poor welfare outcomes, including dog relinquishment... Read More about Lasting lockdown love? Problem behaviour and pandemic and non-pandemic related risk factors influencing the owner-dog relationship in a UK cohort of dogs reaching early adulthood.

Whole genome sequencing identifies novel candidate genetic variants in canine stomatocytosis (2025)
Journal Article
Wallace, M., Falcone, S., Castillo, D., Williams, T., & Davison, L. (2025). Whole genome sequencing identifies novel candidate genetic variants in canine stomatocytosis. Gene, 149314. https://doi.org/10.1016/j.gene.2025.149314

Abstract
Stomatocytosis is a rare spectrum of red blood cell (RBC) disorders. In humans, stomatocytosis is typically caused by genetic changes in specific ion exchange and transport genes. Stomatocytosis has been identified in dogs, however the unde... Read More about Whole genome sequencing identifies novel candidate genetic variants in canine stomatocytosis.

Aberrant Right Subclavian Arteries in Dogs Have a Prevalence of 1.2% and Are More Likely to be an Incidental Finding on Computed Tomographic Studies of the Thorax (2025)
Journal Article
Jones, C., Klever, J., Cordella, A., Fouriez-Lablee, V., Watton, T., & Llabres-Diaz, F. (2025). Aberrant Right Subclavian Arteries in Dogs Have a Prevalence of 1.2% and Are More Likely to be an Incidental Finding on Computed Tomographic Studies of the Thorax. Veterinary Radiology and Ultrasound, 66(2), https://doi.org/10.1111/vru.70011

Aberrant right subclavian arteries (ARSAs) are a form of vascular ring anomaly (VRA) in dogs and the most common VRA in people. To date, there has been no large-scale study on ARSA in dogs and their potential clinical significance. For part one, a si... Read More about Aberrant Right Subclavian Arteries in Dogs Have a Prevalence of 1.2% and Are More Likely to be an Incidental Finding on Computed Tomographic Studies of the Thorax.

Extracellular matrix: Dystroglycan interactions-Roles for the dystrophin-associated glycoprotein complex in skeletal tissue dynamics (2025)
Journal Article
Hopkinson, M., & Pitsillides, A. (2025). Extracellular matrix: Dystroglycan interactions-Roles for the dystrophin-associated glycoprotein complex in skeletal tissue dynamics. International Journal of Experimental Pathology, 106(2), https://doi.org/10.1111/iep.12525

Contributions made by the dystrophin-associated glycoprotein complex (DGC) to cell-cell and cell-extracellular matrix (ECM) interactions are vital in development, homeostasis and pathobiology. This review explores how DGC functions may extend to skel... Read More about Extracellular matrix: Dystroglycan interactions-Roles for the dystrophin-associated glycoprotein complex in skeletal tissue dynamics.

Equine adult, fetal and ESC-tenocytes have differential migratory, proliferative and gene expression responses to factors upregulated in the injured tendon (2025)
Journal Article
Beaumont, R. E., Smith, E. J., David, C., Paterson, Y. Z., Faull, E., & Guest, D. J. (2025). Equine adult, fetal and ESC-tenocytes have differential migratory, proliferative and gene expression responses to factors upregulated in the injured tendon. Cells & Development, https://doi.org/10.1016/j.cdev.2025.204003

Tendon injuries are a common problem in humans and horses. There is a high re-injury rate in both species due to the poor regeneration of adult tendon and the resulting formation of scar tissue. In contrast, fetal tendon injuries undergo scarless reg... Read More about Equine adult, fetal and ESC-tenocytes have differential migratory, proliferative and gene expression responses to factors upregulated in the injured tendon.

Challenges in developing a split drive targeting dsx for the genetic control of the invasive malaria vector Anopheles stephensi (2025)
Journal Article
Larrosa-Godall, M., Ang, J., Leftwich, P., Gonzalez, E., Shackleford, L., Nevard, K., Noad, R., Anderson, M., & Alphey, L. (2025). Challenges in developing a split drive targeting dsx for the genetic control of the invasive malaria vector Anopheles stephensi. Parasites and Vectors, 18(1), https://doi.org/10.1186/s13071-025-06688-0

BackgroundAnopheles stephensi is a competent malaria vector mainly present in southern Asia and the Arabian Peninsula. Since 2012, it has invaded several countries of eastern Africa, creating an emerging risk of urban transmission. Urgent efforts are... Read More about Challenges in developing a split drive targeting dsx for the genetic control of the invasive malaria vector Anopheles stephensi.

Phenotype-Specific Semi-Mechanistic Modelling of Florfenicol Time-Kill Curves in G. parasuis Compared to Other Respiratory Pathogens (2025)
Journal Article
Mead, A., Hughes, A., Azzariti, S., Toutain, P.-L., & Pelligand, L. (2025). Phenotype-Specific Semi-Mechanistic Modelling of Florfenicol Time-Kill Curves in G. parasuis Compared to Other Respiratory Pathogens. Journal of Veterinary Pharmacology and Therapeutics, https://doi.org/10.1111/jvp.13500

This study examines the pharmacodynamics (PD) of florfenicol (FFN) for treating porcine respiratory diseases by comparing its effects on Glaesserella parasuis, Actinobacillus pleuropneumoniae, and Pasteurella multocida. In vitro time-kill assays and... Read More about Phenotype-Specific Semi-Mechanistic Modelling of Florfenicol Time-Kill Curves in G. parasuis Compared to Other Respiratory Pathogens.

Climate change and campylobacteriosis from chicken meat: the changing risk factors and their importance (2025)
Journal Article
Queenan, K., & Haesler, B. (in press). Climate change and campylobacteriosis from chicken meat: the changing risk factors and their importance. Food Control, https://doi.org/10.1016/j.foodcont.2025.111193

Global consumption of chicken meat is currently the highest consumed meat per capita, and it continues to rise. Campylobacteriosis is one of the most reported gastrointestinal conditions, typically associated with chicken meat consumption. Cases are... Read More about Climate change and campylobacteriosis from chicken meat: the changing risk factors and their importance.

Laboratory capacity-building during COVID-19 in Somalia: improving access to essential diagnostics for national health security in a fragile setting (2025)
Journal Article
Figuereo, S., Mohamed, S., Takele, D., Sheikh, A., Abera, S., Mohamed, A., Lubogo, M., Abukar, H., Karanja, M., Bangura, S., Fayad, A., Adam, A., Osman, A., & Malik, S. (2025). Laboratory capacity-building during COVID-19 in Somalia: improving access to essential diagnostics for national health security in a fragile setting. Journal of epidemiology and global health, 15(1), https://doi.org/10.1007/s44197-025-00350-9

IntroductionEven before the COVID-19 pandemic, Somalia's national laboratory services had insufficient diagnostic capacities. We describe how the country moved rapidly from no testing capability to molecular testing and genomic sequencing for severe... Read More about Laboratory capacity-building during COVID-19 in Somalia: improving access to essential diagnostics for national health security in a fragile setting.

Clinical outcomes and complications of tracheal resection and anastomosis in dogs and cats: 20 cases (2009–2022) (2025)
Journal Article
Gaudio, E., Lipscomb, V. J., Cantatore, M., Blacklock, K., Gosling, M., Jack, M., Charlesworth, T., & Shales, C. J. (2025). Clinical outcomes and complications of tracheal resection and anastomosis in dogs and cats: 20 cases (2009–2022). Journal of Small Animal Practice, n/a(n/a), https://doi.org/10.1111/jsap.13830

Objectives To report clinical presentation, short-term outcome and complications of tracheal resection and anastomosis in dogs and cats. Materials and Methods Clinical records of pets treated with tracheal resection and anastomosis in seven UK-based... Read More about Clinical outcomes and complications of tracheal resection and anastomosis in dogs and cats: 20 cases (2009–2022).