Uncovering the molecular signature of feline diffuse iris melanoma through transcriptomic analysis of disease severity
(2025)
Journal Article
Kayes, D., Blacklock, B., McGeachan, R., Scurrell, E., Donnelly, K., Murphy, L., Fawkes, A., Clark, R., Meynert, A., Becher, H., Pittaway, R., Fricker, G., Pont, R., Suárez-Bonnet, A., & Blacklock, K. (2025). Uncovering the molecular signature of feline diffuse iris melanoma through transcriptomic analysis of disease severity. Scientific Reports, 15(1), https://doi.org/10.1038/s41598-025-09632-5
Feline diffuse iris melanoma (FDIM) is the most common primary ocular tumour in cats, with metastatic disease occurring in 19-63% of patients. Greater intraocular invasion correlates with increased mortality. No effective therapeutics exist for metas...
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