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Welcome to RVC Repository

RVC Research Online is a repository of the research outputs produced by staff from the Royal Veterinary College (RVC). The aims of the repository are (i) to provide an institutional archive of RVC's research outputs, (ii) to provide access to these outputs and support open science, and (iii) to increase the reach and impact of RVC's research.



Latest Additions

Outcome of lip-to-lid subdermal plexus flaps to reconstruct defects of the lower eyelid in dogs and cats: 46 cases (2005-2022) (2025)
Journal Article
Sesana, A., Bietzk, E., Rossanese, M., Buracco, P., Cinti, F., Montinaro, V., Everson, R., Massari, F., Almansa-Ruiz, J., Heathcote, N., Chiti, L., Rushton, J., & Das, S. (2025). Outcome of lip-to-lid subdermal plexus flaps to reconstruct defects of the lower eyelid in dogs and cats: 46 cases (2005-2022). Journal of Small Animal Practice, https://doi.org/10.1111/jsap.13914

ObjectivesTo report the outcome of lip-to-lid subdermal plexus flaps in dogs and cats, the surgical and ophthalmic complications and their incidence, and the occurrence of the complications in relation to risk factors.Materials and MethodsMedical rec... Read More about Outcome of lip-to-lid subdermal plexus flaps to reconstruct defects of the lower eyelid in dogs and cats: 46 cases (2005-2022).

CXCR3-mediated natural killer cell infiltration exacerbates white matter injury after intracerebral haemorrhage (2025)
Journal Article
Ng, A., Zhang, C., Lam, T., Kiang, K., Ng, V., Zhu, Z., Liu, J., Tu, W., Tang, W., Chau, K., Man, K., & Leung, G. (2025). CXCR3-mediated natural killer cell infiltration exacerbates white matter injury after intracerebral haemorrhage. Brain, https://doi.org/10.1093/brain/awaf108

Intracerebral haemorrhage (ICH), a subtype of stroke, carries a grim prognosis. The inflammatory response during the early phase of ICH is a major perpetuator of neurological damage. Recent clinical studies suggest possible participation of the CXC c... Read More about CXCR3-mediated natural killer cell infiltration exacerbates white matter injury after intracerebral haemorrhage.

Injuries to the superficial digital flexor tendon branches: Clinical presentation, diagnostic features and outcome (2025)
Journal Article
Spiesshofer, P., O'Hara, V., Garrett, K., & Smith, R. (2025). Injuries to the superficial digital flexor tendon branches: Clinical presentation, diagnostic features and outcome. Equine Veterinary Education, https://doi.org/10.1111/eve.14205

BackgroundInjury of the superficial digital flexor tendon (SDFT) branch is uncommon and the response to different treatments has not been reported.ObjectivesThe aim of this study was to describe the clinical presentation, diagnostic features, treatme... Read More about Injuries to the superficial digital flexor tendon branches: Clinical presentation, diagnostic features and outcome.

Uncovering the molecular signature of feline diffuse iris melanoma through transcriptomic analysis of disease severity (2025)
Journal Article
Kayes, D., Blacklock, B., McGeachan, R., Scurrell, E., Donnelly, K., Murphy, L., Fawkes, A., Clark, R., Meynert, A., Becher, H., Pittaway, R., Fricker, G., Pont, R., Suárez-Bonnet, A., & Blacklock, K. (2025). Uncovering the molecular signature of feline diffuse iris melanoma through transcriptomic analysis of disease severity. Scientific Reports, 15(1), https://doi.org/10.1038/s41598-025-09632-5

Feline diffuse iris melanoma (FDIM) is the most common primary ocular tumour in cats, with metastatic disease occurring in 19-63% of patients. Greater intraocular invasion correlates with increased mortality. No effective therapeutics exist for metas... Read More about Uncovering the molecular signature of feline diffuse iris melanoma through transcriptomic analysis of disease severity.

Unwelcome neighbours: Tracking the transmission of Streptococcus equi in the United Kingdom horse population (2025)
Journal Article
McGlennon, A., Verheyen, K., Newton, J., van Tonder, A., Wilson, H., Parkhill, J., de Brauwere, N., Frosth, S., & Waller, A. (2025). Unwelcome neighbours: Tracking the transmission of Streptococcus equi in the United Kingdom horse population. Equine Veterinary Journal, https://doi.org/10.1111/evj.14558

Background: Strangles (Streptococcus equi infection) remains endemic in the UK, with similar to 300 laboratory diagnoses annually. Sub-clinically infected long-term carriers are considered a key driver of endemicity. Analysing genomes of circulating... Read More about Unwelcome neighbours: Tracking the transmission of Streptococcus equi in the United Kingdom horse population.