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Welcome to RVC Repository

RVC Research Online is a repository of the research outputs produced by staff from the Royal Veterinary College (RVC). The aims of the repository are (i) to provide an institutional archive of RVC's research outputs, (ii) to provide access to these outputs and support open science, and (iii) to increase the reach and impact of RVC's research.



Latest Additions

Somatic GNAQ, CTNNB1, and CACNA1C Mutations in Cat Aldosterone-Secreting Tumors (2024)
Journal Article
Watson, A., Syme, H., & Brown, M. (2024). Somatic GNAQ, CTNNB1, and CACNA1C Mutations in Cat Aldosterone-Secreting Tumors. Hypertension, 81(12), 2489-2500. https://doi.org/10.1161/HYPERTENSIONAHA.124.23501

BACKGROUND:Primary aldosteronism (PA) is a common cause of human hypertension. Somatic mutations in KCNJ5, CACNA1D, ATP1A1, and ATP2B3 are found in at least 80% of aldosterone-producing adenomas, which cause unilateral PA in humans. Somatic mutations... Read More about Somatic GNAQ, CTNNB1, and CACNA1C Mutations in Cat Aldosterone-Secreting Tumors.

Fetal growth restriction and placental defects in obese mice are associated with impaired decidualisation: the role of increased leptin signalling modulators SOCS3 and PTPN2 (2024)
Journal Article
Walewska, E., Makowczenko, K., Witek, K., Laniecka, E., Molcan, T., Alvarez-Sanchez, A., Kelsey, G., Perez-Garcia, V., & Galvao, A. (2024). Fetal growth restriction and placental defects in obese mice are associated with impaired decidualisation: the role of increased leptin signalling modulators SOCS3 and PTPN2. Cellular and Molecular Life Sciences, 81(1), https://doi.org/10.1007/s00018-024-05336-7

Decidualisation of the endometrium is a key event in early pregnancy, which enables embryo implantation. Importantly, the molecular processes impairing decidualisation in obese mothers are yet to be characterised. We hypothesise that impaired decidua... Read More about Fetal growth restriction and placental defects in obese mice are associated with impaired decidualisation: the role of increased leptin signalling modulators SOCS3 and PTPN2.

Clustering broiler farmers based on their behavioural differences towards biosecurity to prevent highly pathogenic avian influenza (2024)
Journal Article
Pao, H., Jackson, E., Yang, T., Tsai, J., Hwang, Y., Sung, W., & Pfeiffer, D. (2024). Clustering broiler farmers based on their behavioural differences towards biosecurity to prevent highly pathogenic avian influenza. One Health, 19, https://doi.org/10.1016/j.onehlt.2024.100852

Highly pathogenic avian influenza (HPAI) is an important zoonotic disease. The study aims to identify farmer behaviour types to inform the design of behaviour change programmes for mitigating the transmission of HPAI. Therefore, the study utilised mu... Read More about Clustering broiler farmers based on their behavioural differences towards biosecurity to prevent highly pathogenic avian influenza.

IHR-PVS National Bridging Workshop for Somalia: An interactive and participatory approach for operationalizing the One Health roadmap (2024)
Journal Article
Osman, A., Saidouni, A., Wambua, L., Mahrous, H., Malik, S., Lubogo, M., van de Weerdt, R., Adam, A., Mohamed, H., Al Makhzoumi, K., Ali, G., Nur, M., Fevre, S., Mucheru, G., Njue, S., Mosindo, A., Sandhaus, K., Wigand, R., Standley, C., Sorrell, E., …Mor, S. (2024). IHR-PVS National Bridging Workshop for Somalia: An interactive and participatory approach for operationalizing the One Health roadmap. One Health, 19, https://doi.org/10.1016/j.onehlt.2024.100858

Background: National Bridging Workshops (NBW) are a tool for reviewing collaboration gaps between line ministries relevant to the One Health framework. Methods: The NBW for Somalia was held on November 11-13, 2023 in Nairobi, Kenya with support from... Read More about IHR-PVS National Bridging Workshop for Somalia: An interactive and participatory approach for operationalizing the One Health roadmap.

Understanding the interests of academics from diverse disciplines to identify the prospective focus for a UK-based transdisciplinary network involving farm-to-fork stakeholders on antimicrobial resistance in agrifood systems: An online survey (2024)
Journal Article
McIntyre, K., Khan, M., Betson, M., Brunton, L., Degiovanni, H., Desbois, A., Eltholth, M., Hurley, P., Morgans, L., Pearl, J., Sakrabani, R., Shortall, O., Watson, K., & Cole, J. (2024). Understanding the interests of academics from diverse disciplines to identify the prospective focus for a UK-based transdisciplinary network involving farm-to-fork stakeholders on antimicrobial resistance in agrifood systems: An online survey. One Health, 19, https://doi.org/10.1016/j.onehlt.2024.100884

Antimicrobial resistance (AMR) evolution and onward transmission of resistance genes is impacted by interrelated biological and social drivers, with evidence and impacts observed across human, animal and environmental One Health domains. Systems-base... Read More about Understanding the interests of academics from diverse disciplines to identify the prospective focus for a UK-based transdisciplinary network involving farm-to-fork stakeholders on antimicrobial resistance in agrifood systems: An online survey.