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Clinical findings, treatment, and outcomes in cats with naturally occurring hypoadrenocorticism: 41 cases (2024)
Journal Article
Roberts, E., Ramsey, I., Gostelow, R., Latysheva, A., Battaglia, L., Silvestrini, P., Benchekroun, G., Brenner, K., Conversy, B., Ferriani, R., Kortum, A., Stammeleer, L., van den Steen, N., Tavares, F., Lieser, J., Hibbert, A., Duclos, A., Bunn, T., Boag, A., Arenas, C., …Fracassi, F. (2025). Clinical findings, treatment, and outcomes in cats with naturally occurring hypoadrenocorticism: 41 cases. Journal of Veterinary Internal Medicine, 39(1), https://doi.org/10.1111/jvim.17243

Background: Hypoadrenocorticism in cats is uncommonly reported. Most reports consist of cats with hyponatremia, hyperkalemia, or both. Hypothesis/Objectives: To describe clinical findings, treatment response, and outcome in cats diagnosed with hypoad... Read More about Clinical findings, treatment, and outcomes in cats with naturally occurring hypoadrenocorticism: 41 cases.

Caregiver-reported increased food motivation and adiposity in dogs receiving antiseizure drugs (2024)
Journal Article
Morros-Nuevo, A., Packer, R., Regan, N., & Raffan, E. (2024). Caregiver-reported increased food motivation and adiposity in dogs receiving antiseizure drugs. Veterinary Record, https://doi.org/10.1002/vetr.4907

BackgroundIdiopathic epilepsy is the most common chronic neurological disease in dogs and requires lifelong administration of antiseizure drugs (ASD). A decreased level of energy and increased food intake and weight gain have been described as long-l... Read More about Caregiver-reported increased food motivation and adiposity in dogs receiving antiseizure drugs.

Aquaculture requires special consideration in National Action Plans for Antimicrobial Resistance (2024)
Journal Article
Desbois, A. P., Brunton, L. A., Henriksson, P. J., Luthman, O., Troell, M., & Green, D. M. (2025). Aquaculture requires special consideration in National Action Plans for Antimicrobial Resistance. Science of the Total Environment, 958, 177785. https://doi.org/10.1016/j.scitotenv.2024.177785

Antimicrobial resistance (AMR) demands collective action to reduce and mitigate its threats. The Quadripartite collaboration of the World Health Organization (WHO), Food and Agriculture Organization of the United Nations (FAO), United Nations Environ... Read More about Aquaculture requires special consideration in National Action Plans for Antimicrobial Resistance.

"Maybe we should think outside the box?" prioritisation of issues with UK not-for-profit canine health and welfare research funding using Delphi expert consensus and gap analysis (2024)
Journal Article
Skipper, A., Packer, R., & O'Neill, D. (2024). "Maybe we should think outside the box?" prioritisation of issues with UK not-for-profit canine health and welfare research funding using Delphi expert consensus and gap analysis. PLoS ONE, 19(12), https://doi.org/10.1371/journal.pone.0313735

Over fifty participants, who together possessed broad research, veterinary and front-line expertise from across the canine health and welfare sector, contributed to a modified Delphi study to identify the highest priority research topics in UK canine... Read More about "Maybe we should think outside the box?" prioritisation of issues with UK not-for-profit canine health and welfare research funding using Delphi expert consensus and gap analysis.

Determination of pharmacokinetic-pharmacodynamic cutoff values of oxytetracycline in calves and adult cattle using population pharmacokinetic modelling (2024)
Journal Article
Winter, E., Pelligand, L., Toutain, P.-L., Lees, P., Milanova, A., & Gehring, R. (in press). Determination of pharmacokinetic-pharmacodynamic cutoff values of oxytetracycline in calves and adult cattle using population pharmacokinetic modelling. Frontiers in Microbiology, https://doi.org/10.3389/fmicb.2024.1498219

In Europe, there is currently no harmonized clinical breakpoint for interpretation of antimicrobial susceptibility testing of oxytetracycline in cattle. The objective of this meta-analysis of oxytetracycline pharmacokinetic (PK) data in cattle was to... Read More about Determination of pharmacokinetic-pharmacodynamic cutoff values of oxytetracycline in calves and adult cattle using population pharmacokinetic modelling.

Epistemic Emotions in Learning: Using Qualitative Inquiry to Explore Implications for Veterinary Educators in Responding to Student Emotions in Their Classrooms (2024)
Journal Article
Davis, R., Kedrowicz, A., Moffett, J., Zaneb, H., & Armitage-Chan, E. (in press). Epistemic Emotions in Learning: Using Qualitative Inquiry to Explore Implications for Veterinary Educators in Responding to Student Emotions in Their Classrooms. Journal of Veterinary Medical Education, https://doi.org/10.3138/jvme-2024-0076

Abstract
Veterinary students frequently experience heightened emotions which can stimulate or compromise learning. The impact of student emotions on educators, or the ways that educators can respond to these is less well known. This has potential im... Read More about Epistemic Emotions in Learning: Using Qualitative Inquiry to Explore Implications for Veterinary Educators in Responding to Student Emotions in Their Classrooms.

Short-term clinical and biochemical responses following treatment with dapagliflozin or ertugliflozin in horses with hyperinsulinemia: A retrospective case series (2024)
Journal Article
Sundra, T., Knowles, E., Rendle, D., Kelty, E., Lester, G., & Rossi, G. (2025). Short-term clinical and biochemical responses following treatment with dapagliflozin or ertugliflozin in horses with hyperinsulinemia: A retrospective case series. Domestic Animal Endocrinology, 90, https://doi.org/10.1016/j.domaniend.2024.106894

The metabolic and lipid profiles of horses treated with sodium-glucose cotransporter 2 inhibitors are not well understood. This retrospective study evaluated blood parameters in hyperinsulinemic horses treated with either ertugliflozin (0.05 mg/kg) o... Read More about Short-term clinical and biochemical responses following treatment with dapagliflozin or ertugliflozin in horses with hyperinsulinemia: A retrospective case series.

Anthropogenic land consolidation intensifies zoonotic host diversity loss and disease transmission in human habitats (2024)
Journal Article
Pei, S., Yu, P., Raghwani, J., Wang, Y., Liu, Z., Li, Y., Cheng, Y., Lin, Q., Song, C., Dharmarajan, G., Faust, C. L., Tian, Y., Xu, Y., Liang, Y., Qu, J., Wei, J., Li, S., Zhang, T., Ma, C., Bharti, N., …Tian, H. (in press). Anthropogenic land consolidation intensifies zoonotic host diversity loss and disease transmission in human habitats. Nature Ecology and Evolution, 9(1), 99-110. https://doi.org/10.1038/s41559-024-02570-x

Microglia contribute to the production of the amyloidogenic ABri peptide in familial British dementia (2024)
Journal Article
Arber, C., Casey, J., Crawford, S., Rambarack, N., Yaman, U., Wiethoff, S., Augustin, E., Piers, T., Price, M., Rostagno, A., Ghiso, J., Lewis, P., Revesz, T., Hardy, J., Pocock, J., Houlden, H., Schott, J., Salih, D., Lashley, T., & Wray, S. (2024). Microglia contribute to the production of the amyloidogenic ABri peptide in familial British dementia. Acta Neuropathologica, 148(1), https://doi.org/10.1007/s00401-024-02820-z

Mutations in ITM2B cause familial British, Danish, Chinese, and Korean dementias. In familial British dementia (FBD), a mutation in the stop codon of the ITM2B gene (also known as BRI2) causes a C-terminal cleavage fragment of the ITM2B/BRI2 protein... Read More about Microglia contribute to the production of the amyloidogenic ABri peptide in familial British dementia.

Preclinical development and characterisation of PP353, a formulation of linezolid for intradiscal administration (2024)
Journal Article
Hagger, G., Guest, S., Birchall, S., Bradley, A., Brindley, C., Corbett, D., Cummings, P., Freire, C., Harris, J., Wise, A., Wood, M., & Czaplewski, L. (2024). Preclinical development and characterisation of PP353, a formulation of linezolid for intradiscal administration. JOR Spine, 7(4), https://doi.org/10.1002/jsp2.70010

IntroductionBacterial infection of the intervertebral disc can lead to vertebral endplate edema known as Modic changes, with associated chronic low back pain. Oral antimicrobial therapy has shown efficacy but relies on prolonged dosing and may not be... Read More about Preclinical development and characterisation of PP353, a formulation of linezolid for intradiscal administration.

A CADASIL NOTCH3 mutation leads to clonal hematopoiesis and expansion of Dnmt3a-R878H hematopoietic clones (2024)
Journal Article
Sánchez-Lanzas, R., Barclay, J., Chardas, A., Kalampalika, F., Jiménez-Pompa, A., Gallipoli, P., & Ganuza, M. (2024). A CADASIL NOTCH3 mutation leads to clonal hematopoiesis and expansion of Dnmt3a-R878H hematopoietic clones. Leukemia, https://doi.org/10.1038/s41375-024-02464-8

Clonal hematopoiesis (CH) is nearly universal in the elderly. The molecular and cellular mechanisms driving CH and the clinical consequences of carrying clonally derived mutant mature blood cells are poorly understood. We recently identified a C223Y... Read More about A CADASIL NOTCH3 mutation leads to clonal hematopoiesis and expansion of Dnmt3a-R878H hematopoietic clones.

Increased susceptibility to diet-induced obesity in female mice impairs ovarian steroidogenesis: The role of elevated leptin signalling on nodal activity inhibition in theca cells (2024)
Journal Article
Wolodko, K., Sentjurc, T., Walewska, E., Laniecka, E., Jura, M., & Galvao, A. (2025). Increased susceptibility to diet-induced obesity in female mice impairs ovarian steroidogenesis: The role of elevated leptin signalling on nodal activity inhibition in theca cells. Molecular Metabolism, 91, https://doi.org/10.1016/j.molmet.2024.102062

Objectives Susceptibility to obesity in humans is driven by the intricate interplay of genetic, environmental and behavioural factors. Moreover, the mechanisms linking maternal obesity to infertility remain largely understudied. In this study, we inv... Read More about Increased susceptibility to diet-induced obesity in female mice impairs ovarian steroidogenesis: The role of elevated leptin signalling on nodal activity inhibition in theca cells.

White paper formatted for Endocrine Oncology NET models meeting 2024 White Paper: the current state of neuroendocrine tumour research models and our future aspirations (2024)
Journal Article
Hien Ear, P., Marinoni, I., Dayton, T., Guenter, R., Quelle, D. E., Battistella, A., Buishand, F. O., Chittaranjan, S., Du, Y.-C. N., Marques, I., Pellegata, N., Sadowski, S. M., Tirosh, A., April-Monn, S., Aurilia, C., Jaskula-Sztul, R., Jesús, M., Moreno, B., Donati, S., English, K. A., …Schrader, J. (2024). White paper formatted for Endocrine Oncology NET models meeting 2024 White Paper: the current state of neuroendocrine tumour research models and our future aspirations. Endocrine Oncology, https://doi.org/10.1530/EO-24-0055