All Outputs (10393)

Endothelial AHR activity prevents lung barrier disruption in viral infection (2023)
Journal Article
Major, J., Crotta, S., Finsterbusch, K., Chakravarty, P., Shah, K., Frederico, B., …Wack, A. (2023). Endothelial AHR activity prevents lung barrier disruption in viral infection. Nature, https://doi.org/10.1038/s41586-023-06287-y

Disruption of the lung endothelial-epithelial cell barrier following respiratory virus infection causes cell and fluid accumulation in the air spaces and compromises vital gas exchange function(1). Endothelial dysfunction can exacerbate tissue damage... Read More about Endothelial AHR activity prevents lung barrier disruption in viral infection.

Macroevolutionary patterns in the pelvis, stylopodium and zeugopodium of megalosauroid theropod dinosaurs and their importance for locomotor function (2023)
Journal Article
Lacerda, M., Bittencourt, J., & Hutchinson, J. (2023). Macroevolutionary patterns in the pelvis, stylopodium and zeugopodium of megalosauroid theropod dinosaurs and their importance for locomotor function. Royal Society Open Science, 10(8), https://doi.org/10.1098/rsos.230481

During the Mesozoic, non-avian theropods represented one of the most successful clades globally distributed, with a wide diversity of forms. An example is the clade Megalosauroidea, which included medium- to large-bodied forms. Here, we analyse the m... Read More about Macroevolutionary patterns in the pelvis, stylopodium and zeugopodium of megalosauroid theropod dinosaurs and their importance for locomotor function.

Effect of Lavage Solution Type on Bronchoalveolar Lavage Fluid Cytology in Clinically Healthy Horses (2023)
Journal Article
Westermann, C. M., de Bie, A. G., Olave, C., de Grauw, J. C., Teske, E., & Couetil, L. L. (in press). Effect of Lavage Solution Type on Bronchoalveolar Lavage Fluid Cytology in Clinically Healthy Horses. Animals, 13(16), 2637. https://doi.org/10.3390/ani13162637

Equine induced pluripotent stem cells are responsive to inflammatory cytokines before and after differentiation into musculoskeletal cell types (2023)
Journal Article
Palomino Lago, E., Jelbert, E. R., Baird, A., Lam, P. Y., & Guest, D. J. (in press). Equine induced pluripotent stem cells are responsive to inflammatory cytokines before and after differentiation into musculoskeletal cell types. In Vitro Cellular and Developmental Biology - Animal, https://doi.org/10.1007/s11626-023-00800-3

DNA methylation networks underlying mammalian traits (2023)
Journal Article
Haghani, A., Li, C. Z., Robeck, T. R., Zhang, J., Lu, A. T., Ablaeva, J., …Horvath, S. (2023). DNA methylation networks underlying mammalian traits. Science, 381(6658), https://doi.org/10.1126/science.abq5693

Phylodynamic approaches to studying avian influenza virus: a review (2023)
Journal Article
Carnegie, L., Raghwani, J., Fournié, G., & Hill, S. (2023). Phylodynamic approaches to studying avian influenza virus: a review. Avian Pathology, https://doi.org/10.1080/03079457.2023.2236568

A machine learning-based image segmentation method to quantify in vitro osteoclast culture endpoints (2023)
Journal Article
Davies, B., Hibbert, A., Roberts, S., Roberts, H., Tickner, J., Holdsworth, G., …Orriss, I. (in press). A machine learning-based image segmentation method to quantify in vitro osteoclast culture endpoints. Calcified Tissue International, https://doi.org/10.1007/s00223-023-01121-z

Universal DNA methylation age across mammalian tissues (2023)
Journal Article
Lu, A. T., Fei, Z., Haghani, A., Robeck, T. R., Zoller, J. A., Li, C. Z., …Horvath, S. (in press). Universal DNA methylation age across mammalian tissues. Nature Aging, 3(9), 1144-1166. https://doi.org/10.1038/s43587-023-00462-6

Dropped-head syndrome in a dog secondary to myopathy of the cervical extensor muscles (2023)
Journal Article
Grapes, N., Llabres-Diaz, F., Vicent, N., De Stefani, A., & De Decker, S. (2023). Dropped-head syndrome in a dog secondary to myopathy of the cervical extensor muscles. Vet Record Case Reports, https://doi.org/10.1002/vrc2.654

A 4-year-old, male, entire Newfoundland was presented for investigation of an acute onset cervical ventroflexion and pyrexia, 4 days following a hip replacement surgery. Neurological examination confirmed prominent cervical ventroflexion characterise... Read More about Dropped-head syndrome in a dog secondary to myopathy of the cervical extensor muscles.

Diagnostic quality of ultrasound-guided fine-needle aspirates samples from the canine liver and spleen is not significantly affected by using 22-, 23-, and 25-gauge needles (2023)
Journal Article
Llanos, C., Holmes, E., White, C., Jasensky, A., & Fitzgerald, E. (2023). Diagnostic quality of ultrasound-guided fine-needle aspirates samples from the canine liver and spleen is not significantly affected by using 22-, 23-, and 25-gauge needles. Veterinary Radiology and Ultrasound, https://doi.org/10.1111/vru.13290

Ultrasound-guided fine-needle aspirates (FNA) of the liver and spleen for cytological analysis are a commonly performed procedure in canine veterinary practice. Based on our review of the literature, this is the first published study investigating wh... Read More about Diagnostic quality of ultrasound-guided fine-needle aspirates samples from the canine liver and spleen is not significantly affected by using 22-, 23-, and 25-gauge needles.

Targeted dosing for susceptible heteroresistant subpopulations may improve rational dosage regimen prediction for colistin in broiler chickens (2023)
Journal Article
Mead, A., Toutain, P., Richez, P., & Pelligand, L. (2023). Targeted dosing for susceptible heteroresistant subpopulations may improve rational dosage regimen prediction for colistin in broiler chickens. Scientific Reports, 13, Article 12822. https://doi.org/10.1038/s41598-023-39727-w

The dosage of colistin for the treatment of enteric E. coli in animals necessitates considering the heteroresistant (HR) nature of the targeted inoculum, described by the presence of a major susceptible population (S1, representing 99.95% of total po... Read More about Targeted dosing for susceptible heteroresistant subpopulations may improve rational dosage regimen prediction for colistin in broiler chickens.

Evidence that pyrophosphate acts as an extracellular signalling molecule to exert direct functional effects on primary osteoblasts and osteoclasts (2023)
Journal Article
Orriss, I., Wheeler-Jones, C., Roberts, S., & Keen, J. (in press). Evidence that pyrophosphate acts as an extracellular signalling molecule to exert direct functional effects on primary osteoblasts and osteoclasts. BONE, https://doi.org/10.1016/j.bone.2023.116868

Development of a body condition index to estimate adiposity in ponies and horses from morphometric measurements (2023)
Journal Article
Menzies-Gow, N., & Knowles, E. (2023). Development of a body condition index to estimate adiposity in ponies and horses from morphometric measurements. Equine Veterinary Journal, https://doi.org/10.1111/evj.13975

Gestation Length is Associated With Early-Life Limb Deformities in Thoroughbred Foals (2023)
Journal Article
Mouncey, R., Arango-Sabogal, J., de Mestre, A., & Verheyen, K. (2023). Gestation Length is Associated With Early-Life Limb Deformities in Thoroughbred Foals. Journal of Equine Veterinary Science, 129, https://doi.org/10.1016/j.jevs.2023.104896

Flexural and angular limb deformities (LD) are an important cause of early-life morbidity and mortality/euthanasia in Thoroughbred foals. The majority are congenital in origin but, to date, their precise aetiology is poorly understood. We hypothesize... Read More about Gestation Length is Associated With Early-Life Limb Deformities in Thoroughbred Foals.

Analysis of lower urinary tract signs and bacteriuria in cats with subcutaneous ureteral bypass systems (2023)
Journal Article
Djoneva, L., Lawson, J., Rutherford, L., & Geddes, R. (2023). Analysis of lower urinary tract signs and bacteriuria in cats with subcutaneous ureteral bypass systems. Vet Record Open, 10(2), https://doi.org/10.1002/vro2.69

ObjectivesDistinguishing bacterial cystitis from subclinical bacteriuria is necessary for feline treatment protocols and antimicrobial stewardship. This can be challenging in cats with subcutaneous ureteral bypass (SUB) systems because they may prese... Read More about Analysis of lower urinary tract signs and bacteriuria in cats with subcutaneous ureteral bypass systems.

Sequential roles for red blood cell binding proteins enable phased commitment to invasion for malaria parasites (2023)
Journal Article
Hart, M. N., Mohring, F., DonVito, S. M., Thomas, J. A., Muller-Sienerth, N., Wright, G. J., …Moon, R. W. (in press). Sequential roles for red blood cell binding proteins enable phased commitment to invasion for malaria parasites. Nature Communications, 14(1), 4619. https://doi.org/10.1038/s41467-023-40357-z

Invasion of red blood cells (RBCs) by Plasmodium merozoites is critical to their continued survival within the host. Two major protein families, the Duffy binding-like proteins (DBPs/EBAs) and the reticulocyte binding like proteins (RBLs/RHs) have be... Read More about Sequential roles for red blood cell binding proteins enable phased commitment to invasion for malaria parasites.

Preliminary investigation into the housing of dwarf hamsters (2023)
Journal Article
Hedley, J., Pettitt, A., & Abeyesinghe, S. (2023). Preliminary investigation into the housing of dwarf hamsters. Veterinary Record, https://doi.org/10.1002/vetr.3170

BackgroundAlthough pet hamsters are widely available, the literature on their husbandry and health is limited, and guidelines for the care of hamsters are variable. This study investigated housing in different dwarf hamster species, focusing on facto... Read More about Preliminary investigation into the housing of dwarf hamsters.

Mechanosignalling pathways that regulate endothelial barrier function (2023)
Journal Article
McQueen, A., & Warboys, C. M. (2023). Mechanosignalling pathways that regulate endothelial barrier function. Current Opinion in Cell Biology, 84, 102213. https://doi.org/10.1016/j.ceb.2023.102213

Blood vessels are lined by a single layer of endothelial cells that provide a barrier between circulating plasma and the underlying tissue. Permeability of endothelial cells is tightly regulated, and increased permeability is associated with a number... Read More about Mechanosignalling pathways that regulate endothelial barrier function.

MicroRNAs Regulate Ca2+ Homeostasis in Murine Embryonic Stem Cells (2023)
Journal Article
Reid, K. M., Sanchez-Nieto, J. M., Terrasse, S., Faccenda, D., Pernaute, B., Campanella, M., …Cobb, B. S. (2023). MicroRNAs Regulate Ca2+ Homeostasis in Murine Embryonic Stem Cells. Cells, 12(15), 1957. https://doi.org/10.3390/cells12151957

MicroRNAs (miRNAs) are important regulators of embryonic stem cell (ESC) biology, and their study has identified key regulatory mechanisms. To find novel pathways regulated by miRNAs in ESCs, we undertook a bioinformatics analysis of gene pathways di... Read More about MicroRNAs Regulate Ca2+ Homeostasis in Murine Embryonic Stem Cells.

Canine insulinomas and their presumed metastases are most conspicuous in the late arterial phase in a triple arterial phase CT protocol (2023)
Journal Article
Skarbek, A., Fouriez-Lablée, V., Dirrig, H., & Llabres-Diaz, F. (2023). Canine insulinomas and their presumed metastases are most conspicuous in the late arterial phase in a triple arterial phase CT protocol. Veterinary Radiology and Ultrasound, https://doi.org/10.1111/vru.13278

Avid arterial enhancement is the commonly described characteristic of canine insulinomas in contrast-enhanced computed tomography (CECT). However, this finding is also reported as inconsistent. The main aim of this study was to investigate in detai... Read More about Canine insulinomas and their presumed metastases are most conspicuous in the late arterial phase in a triple arterial phase CT protocol.