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Large granular lymphocyte lymphoma in 65 dogs (2005-2023) (2023)
Journal Article
Yale, A., Crawford, A., Gramer, I., Guillen, A., Desmas, I., & Holmes, E. (2023). Large granular lymphocyte lymphoma in 65 dogs (2005-2023). Veterinary and Comparative Oncology, https://doi.org/10.1111/vco.12959

Large granular lymphocyte lymphoma (LGLL) is a rare form of lymphoma in dogs. Limited information exists regarding presentation, treatment response, and outcome. The aim of this single-institute, retrospective study was to characterise clinical prese... Read More about Large granular lymphocyte lymphoma in 65 dogs (2005-2023).

Effects of individual and pair housing of calves on long term heifer production on a UK commercial dairy farm (2023)
Journal Article
Mahendran, S., Blackie, N., Wathes, D. C., & Booth, R. (in press). Effects of individual and pair housing of calves on long term heifer production on a UK commercial dairy farm. Animals, https://doi.org/10.3390/ani14010125

Pair housing of pre-weaning dairy calves has previously demonstrated positive impacts on their growth, health and behaviour, but longer-term effects on production are still relatively unknown. This study followed a cohort of 431 Holstein heifers recr... Read More about Effects of individual and pair housing of calves on long term heifer production on a UK commercial dairy farm.

Using a Whole Genome Co- expression Network to Inform the Functional Characterisation of Predicted Genomic Elements from Mycobacterium tuberculosis Transcriptomic Data (2023)
Journal Article
Stiens, J., Yi Tan, Y., Joyce, R., Arnvig, K. B., Kendall, S. L., & Nobeli, I. (in press). Using a Whole Genome Co- expression Network to Inform the Functional Characterisation of Predicted Genomic Elements from Mycobacterium tuberculosis Transcriptomic Data. Molecular Microbiology, https://doi.org/10.1111/mmi.15055

A whole genome co-expression network was created using Mycobacterium tuberculosis transcriptomic data from publicly available RNA-sequencing experiments covering a wide variety of experimental conditions. The network includes expressed regions with... Read More about Using a Whole Genome Co- expression Network to Inform the Functional Characterisation of Predicted Genomic Elements from Mycobacterium tuberculosis Transcriptomic Data.

CellShip: An Ambient Temperature Transport and Short-Term Storage Medium for Mammalian Cell Cultures (2023)
Journal Article
Buick, E., Mead, A., Alhubaysh, A., Bou Assi, P., Das, P., Dayus, J., …Farnaud, S. (in press). CellShip: An Ambient Temperature Transport and Short-Term Storage Medium for Mammalian Cell Cultures. Biopreservation and Biobanking, https://doi.org/10.1089/bio.2023.0100

Cell culture is a critical platform for numerous research and industrial processes. However, methods for transporting cells are largely limited to cryopreservation, which is logistically challenging, requires the use of potentially cytotoxic cryopres... Read More about CellShip: An Ambient Temperature Transport and Short-Term Storage Medium for Mammalian Cell Cultures.

Multi-ancestry genome-wide association meta-analysis of Parkinson's disease (2023)
Journal Article
Kim, J., Vitale, D., Otani, D., Lian, M., Heilbron, K., Aslibekyan, S., …Mata, I. (2023). Multi-ancestry genome-wide association meta-analysis of Parkinson's disease. Nature Genetics, https://doi.org/10.1038/s41588-023-01584-8

Although over 90 independent risk variants have been identified for Parkinson's disease using genome-wide association studies, most studies have been performed in just one population at a time. Here we performed a large-scale multi-ancestry meta-anal... Read More about Multi-ancestry genome-wide association meta-analysis of Parkinson's disease.

A Functional Single-Nucleotide Polymorphism Upstream of the Collagen Type III Gene Is Associated with Catastrophic Fracture Risk in Thoroughbred Horses (2023)
Journal Article
Lago, E. P., Baird, A., Blott, S. C., Mcphail, R. E., Ross, A. C., Durward-Akhurst, S. A., & Guest, D. J. (2023). A Functional Single-Nucleotide Polymorphism Upstream of the Collagen Type III Gene Is Associated with Catastrophic Fracture Risk in Thoroughbred Horses. Animals, 14(1), 116. https://doi.org/10.3390/ani14010116

Fractures caused by bone overloading are a leading cause of euthanasia in Thoroughbred racehorses. The risk of fatal fracture has been shown to be influenced by both environmental and genetic factors but, to date, no specific genetic mechanisms unde... Read More about A Functional Single-Nucleotide Polymorphism Upstream of the Collagen Type III Gene Is Associated with Catastrophic Fracture Risk in Thoroughbred Horses.

Diagnosis and surgical management of a type IV<i>b</i> dermoid sinus in a Cavalier King Charles Spaniel (2023)
Journal Article
Danciu, C., Briola, C., Volckaert, V., Mccready, D., Pittaway, R., & Fitzmaurice, S. (2023). Diagnosis and surgical management of a type IVb dermoid sinus in a Cavalier King Charles Spaniel. Vet Record Case Reports, https://doi.org/10.1002/vrc2.786

A 6-year-old, male, neutered Cavalier King Charles Spaniel dog was referred with a 4-year history of an intermittently draining fistula on the midline of the frontal bones of the skull. Magnetic resonance imaging and computed tomography scan of the h... Read More about Diagnosis and surgical management of a type IV<i>b</i> dermoid sinus in a Cavalier King Charles Spaniel.

Differential LRRK2 Signalling and Gene Expression in WT-LRRK2 and G2019S-LRRK2 Mouse Microglia Treated with Zymosan and MLi2 (2023)
Journal Article
Nazish, I., Mamais, A., Mallach, A., Bettencourt, C., Kaganovich, A., Warner, T., …Bandopadhyay, R. (2023). Differential LRRK2 Signalling and Gene Expression in WT-LRRK2 and G2019S-LRRK2 Mouse Microglia Treated with Zymosan and MLi2. Cells, 13(1), https://doi.org/10.3390/cells13010053

Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene cause autosomal dominant Parkinson's disease (PD), with the most common causative mutation being the LRRK2 p.G2019S within the kinase domain. LRRK2 protein is highly expressed in the human br... Read More about Differential LRRK2 Signalling and Gene Expression in WT-LRRK2 and G2019S-LRRK2 Mouse Microglia Treated with Zymosan and MLi2.

Post-Thaw Storage Temperature Influenced Boar Sperm Quality and Lifespan through Apoptosis and Lipid Peroxidation (2023)
Journal Article
Li, J., Li, J., Wang, S., Ju, H., Chen, S., Basioura, A., …Zhu, J. (2024). Post-Thaw Storage Temperature Influenced Boar Sperm Quality and Lifespan through Apoptosis and Lipid Peroxidation. Animals, 14(1), https://doi.org/10.3390/ani14010087

Simple Summary Frozen-thawed boar semen has not been widely used due to the deleterious effects of freezing on sperm quality and fertility. Extensive attempts have been made to improve post-thaw sperm quality because the short lifespan of frozen and... Read More about Post-Thaw Storage Temperature Influenced Boar Sperm Quality and Lifespan through Apoptosis and Lipid Peroxidation.

Associations between turn out practices and rates of musculoskeletal disease and injury in Thoroughbred foals and yearlings on stud farms in the United Kingdom. (2023)
Journal Article
Mouncey, R., Arango-Sabogal, J., de Mestre, A., & Verheyen, K. (in press). Associations between turn out practices and rates of musculoskeletal disease and injury in Thoroughbred foals and yearlings on stud farms in the United Kingdom. Equine Veterinary Journal, https://doi.org/10.1111/evj.14038

Abstract Background: Early-life locomotor activity during turn out may alter susceptibility to musculoskeletal disease and injury via modulation of behaviors and tissue development during growth. Objectives: Investigate associations between turn o... Read More about Associations between turn out practices and rates of musculoskeletal disease and injury in Thoroughbred foals and yearlings on stud farms in the United Kingdom..

Thyme, Oregano, and Garlic Essential Oils and Their Main Active Compounds Influence <i>Eimeria tenella</i> Intracellular Development (2023)
Journal Article
Felici, M., Tugnoli, B., De Hoest-Thompson, C., Piva, A., Grilli, E., & Marugan-Hernandez, V. (2024). Thyme, Oregano, and Garlic Essential Oils and Their Main Active Compounds Influence Eimeria tenella Intracellular Development. Animals, 14(1), https://doi.org/10.3390/ani14010077

Coccidiosis poses a significant challenge in poultry production and is typically managed with ionophores and chemical anticoccidials. However, the emergence of drug resistance and limitations on their use have encouraged the exploration of alternativ... Read More about Thyme, Oregano, and Garlic Essential Oils and Their Main Active Compounds Influence <i>Eimeria tenella</i> Intracellular Development.

Highly pathogenic avian influenza virus H5N1 infection in skua and gulls in the United Kingdom, 2022 (2023)
Journal Article
Lean, F., Falchieri, M., Furman, N., Tyler, G., Robinson, C., Holmes, P., …Núñez, A. (2023). Highly pathogenic avian influenza virus H5N1 infection in skua and gulls in the United Kingdom, 2022. Veterinary Pathology, https://doi.org/10.1177/03009858231217224

The reemergence of the highly pathogenic avian influenza virus (HPAIV) subtype H5N1 in the United Kingdom in 2021-2022 has caused unprecedented epizootic events in wild birds and poultry. During the summer of 2022, there was a shift in virus transmis... Read More about Highly pathogenic avian influenza virus H5N1 infection in skua and gulls in the United Kingdom, 2022.

Presence and size of synovial masses within the navicular bursa correlate well between MRI and bursoscopy and have a guarded prognosis (2023)
Journal Article
Giorio, M. E., Graham, R. J., Berner, D., O'Neill, H. D., & Bladon, B. M. (2023). Presence and size of synovial masses within the navicular bursa correlate well between MRI and bursoscopy and have a guarded prognosis. Equine Veterinary Journal, https://doi.org/10.1111/evj.14040

Background: Focal hyperintense lesions within the navicular bursa emanating from the dorsal border of the deep digital flexor tendon (DDFT) can be recognised on T1-weighted magnetic resonance images (MRI) and have been attributed to lameness in horse... Read More about Presence and size of synovial masses within the navicular bursa correlate well between MRI and bursoscopy and have a guarded prognosis.

Small RNA signatures of the anterior cruciate ligament from patients with knee joint osteoarthritis (2023)
Journal Article
Kharaz, Y., Zamboulis, D., Fang, Y., Welting, T., Peffers, M., & Comerford, E. (2023). Small RNA signatures of the anterior cruciate ligament from patients with knee joint osteoarthritis. Frontiers in Molecular Biosciences, 10, https://doi.org/10.3389/fmolb.2023.1266088

Introduction: The anterior cruciate ligament (ACL) is susceptible to degeneration, resulting in joint pain, reduced mobility, and osteoarthritis development. There is currently a paucity of knowledge on how anterior cruciate ligament degeneration and... Read More about Small RNA signatures of the anterior cruciate ligament from patients with knee joint osteoarthritis.

Professional Identity of Pakistani Veterinary Students: Conceptualization and Negotiation (2023)
Journal Article
Zaneb, H., & Armitage-Chan, E. (2023). Professional Identity of Pakistani Veterinary Students: Conceptualization and Negotiation. Journal of Veterinary Medical Education, 50(6), 685-693. https://doi.org/10.3138/jvme-2022-0064

Most work on the professional identity of veterinary and medical professionals has been conceptualized in the US and Europe. It reports professional identity formation to be highly individualized, triggered by experiences of identity distress, and id... Read More about Professional Identity of Pakistani Veterinary Students: Conceptualization and Negotiation.

Multimodal pain management in a dog with oral fibrosarcoma (2023)
Journal Article
Hjalmarsson, L., Bianchi, C., & Stathopoulou, T. (in press). Multimodal pain management in a dog with oral fibrosarcoma. Vet Record Case Reports, https://doi.org/10.1002/vrc2.785

An-year-old lurcher presented at the Pain Clinic of the Queen Mother Hospital following a-month history of progressive right-sided facial pain that was poorly responsive to multimodal oral analgesia. Initial investigations had revealed dental changes... Read More about Multimodal pain management in a dog with oral fibrosarcoma.

The PfRCR complex bridges malaria parasite and erythrocyte during invasion (2023)
Journal Article
Farrell, B., Alam, N., Hart, M. N., Jamwal, A., Ragotte, R. J., Walters-Morgan, H., …Higgins, M. K. (2023). The PfRCR complex bridges malaria parasite and erythrocyte during invasion. Nature, https://doi.org/10.1038/s41586-023-06856-1

The symptoms of malaria occur during the blood stage of infection, when parasites invade and replicate within human erythrocytes. The PfPCRCR complex1, containing PfRH5 (refs. 2,3), PfCyRPA, PfRIPR, PfCSS and PfPTRAMP, is essential for erythrocyte in... Read More about The PfRCR complex bridges malaria parasite and erythrocyte during invasion.

Diagnostic imaging descriptions and prevalence of presumed phrenic lymph nodes in dogs (2023)
Journal Article
Cordella, A., Stock, E., Cornillie, P., Fouriez-Lablée, V., Skarbek, A., Germonpré, J., & Saunders, J. (2023). Diagnostic imaging descriptions and prevalence of presumed phrenic lymph nodes in dogs. Veterinary Radiology and Ultrasound, https://doi.org/10.1111/vru.13320

The phrenic lymph node (PLN) has been described in bovine, equine, and feline anatomic references but descriptions in canine anatomic references are currently lacking. Authors have observed a well-defined, soft tissue attenuating, contrast-enhancing... Read More about Diagnostic imaging descriptions and prevalence of presumed phrenic lymph nodes in dogs.

Surgical treatment of canine urethral prolapse <i>via</i> urethropexy or resection and anastomosis (2023)
Journal Article
Healy, D., Rizkallal, C., Rossanese, M., McLarnon, P., Vallefuoco, R., Murgia, D., …Cantatore, M. (2023). Surgical treatment of canine urethral prolapse via urethropexy or resection and anastomosis. Journal of Small Animal Practice, https://doi.org/10.1111/jsap.13690

Objectives: The objective was to report and compare the complications and recurrence rates of urethral prolapse in dogs when treated with urethropexy, resection and anastomosis or a combined surgical technique. Study design: Retrospective study. Mate... Read More about Surgical treatment of canine urethral prolapse <i>via</i> urethropexy or resection and anastomosis.