Galleria mellonella as an infection model for the virulent Mycobacterium tuberculosis H37Rv (2022)
Journal Article
Asai, M., Li, Y., Spiropoulos, J., Cooley, W., Everest, D. J., Kendall, S., …Newton, S. M. (2022). Galleria mellonella as an infection model for the virulent Mycobacterium tuberculosis H37Rv. Virulence, https://doi.org/10.1080/21505594.2022.2119657

Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), is a leading cause of infectious disease mortality. Animal infection models have contributed substantially to our understanding of TB, yet their biological and non-biological limitation... Read More about Galleria mellonella as an infection model for the virulent Mycobacterium tuberculosis H37Rv.

Defining the genes required for survival of Mycobacterium bovis in the bovine host offers novel insights into the genetic basis of survival of pathogenic mycobacteria (2022)
Journal Article
Gibson, A. J., Stiens, J., Passmore, I. J., Faulkner, V., Miculob, J., Willcocks, S., …Kendall, S. L. (2022). Defining the genes required for survival of Mycobacterium bovis in the bovine host offers novel insights into the genetic basis of survival of pathogenic mycobacteria. mBio, https://doi.org/10.1128/mbio.00672-22

Tuberculosis has severe impacts in both humans and animals. Understanding the genetic basis of survival of both Mycobacterium tuberculosis, the human adapted species, and Mycobacterium bovis, the animal adapted species is crucial to deciphering the b... Read More about Defining the genes required for survival of Mycobacterium bovis in the bovine host offers novel insights into the genetic basis of survival of pathogenic mycobacteria.

Challenges in defining the functional, non‐coding, expressed genome of members of the Mycobacterium tuberculosis complex (2021)
Journal Article
Stiens, J., Arnvig, K. B., Kendall, S. L., & Nobeli, I. (2022). Challenges in defining the functional, non‐coding, expressed genome of members of the Mycobacterium tuberculosis complex. Molecular Microbiology, 117(1), 20-31. https://doi.org/10.1111/mmi.14862

A definitive transcriptome atlas for the non-coding expressed elements of the members of the Mycobacterium tuberculosis complex (MTBC) does not exist. Incomplete lists of non-coding transcripts can be obtained for some of the reference genomes (e.g.,... Read More about Challenges in defining the functional, non‐coding, expressed genome of members of the Mycobacterium tuberculosis complex.

Probing differences in gene essentiality between the human and animal adapted (2021)
Journal Article
Gibson, A. J., Passmore, I. J., Faulkner, V., Xia, D., Nobeli, I., Stiens, J., …Kendall, S. L. (2021). Probing differences in gene essentiality between the human and animal adapted. Frontiers in Veterinary Science,

Members of the Mycobacterium tuberculosis complex (MTBC) show distinct host adaptations, preferences and phenotypes despite being >99% identical at the nucleic acid level. Previous studies have explored gene expression changes between the members, ho... Read More about Probing differences in gene essentiality between the human and animal adapted.

Molecular basis for DarT ADP-ribosylation of a DNA base (2021)
Journal Article
Schuller, M., Butler, R., Ariza, A., Tromans-Coia, C., Jankevicius, G., Claridge, T., …Ahel, I. (2021). Molecular basis for DarT ADP-ribosylation of a DNA base. Nature, https://doi.org/10.1038/s41586-021-03825-4

ADP-ribosyltransferases (ARTs) utilise NAD+ to catalyse substrate ADP-ribosylation, thereby regulating cellular pathways or contributing to toxin-mediated pathogenicity of bacteria. Reversible ADP-ribosylation has traditionally been considered a prot... Read More about Molecular basis for DarT ADP-ribosylation of a DNA base.

A Novel TetR-Like Transcriptional Regulator Is Induced in Acid-Nitrosative Stress and Controls Expression of an Efflux Pump in Mycobacteria (2017)
Journal Article
Perrone, F., De Siena, B., Muscariello, L., Kendall, S. L., Waddell, S. J., & Sacco, M. (2017). A Novel TetR-Like Transcriptional Regulator Is Induced in Acid-Nitrosative Stress and Controls Expression of an Efflux Pump in Mycobacteria. Frontiers in Microbiology, 8(2039), https://doi.org/10.3389/fmicb.2017.02039

The Structure of the Transcriptional Repressor KstR in Complex with CoA Thioester Cholesterol Metabolites Sheds Light on the Regulation of Cholesterol Catabolism in Mycobacterium tuberculosis (2016)
Journal Article
Ho, N. A. T., Dawes, S. S., Crowe, A. M., Casabon, I., Gao, C., Kendall, S. L., …Lott, J. S. (2016). The Structure of the Transcriptional Repressor KstR in Complex with CoA Thioester Cholesterol Metabolites Sheds Light on the Regulation of Cholesterol Catabolism in Mycobacterium tuberculosis. Journal of Biological Chemistry, 291(14), 7256-7266. https://doi.org/10.1074/jbc.M115.707760

Cholesterol can be a major carbon source for Mycobacterium tuberculosis during infection, both at an early stage in the macrophage phagosome and later within the necrotic granuloma. KstR is a highly conserved TetR family transcriptional repressor tha... Read More about The Structure of the Transcriptional Repressor KstR in Complex with CoA Thioester Cholesterol Metabolites Sheds Light on the Regulation of Cholesterol Catabolism in Mycobacterium tuberculosis.

Global analyses of TetR family transcriptional regulators in mycobacteria indicates conservation across species and diversity in regulated functions (2015)
Journal Article
Balhana, R. J. C., Singla, A., Sikder, M. H., Withers, M., & Kendall, S. L. (2015). Global analyses of TetR family transcriptional regulators in mycobacteria indicates conservation across species and diversity in regulated functions. BMC Genomics, 16, 479. https://doi.org/10.1186/s12864-015-1696-9

Purification, crystallization and preliminary X-ray crystallographic studies of KstR2 (keto-steroid regulatory protein) from Mycobacterium tuberculosis (2014)
Journal Article
Dawes, S. S., Kendall, S. L., Baker, E. N., & Lott, J. S. (2014). Purification, crystallization and preliminary X-ray crystallographic studies of KstR2 (keto-steroid regulatory protein) from Mycobacterium tuberculosis. https://doi.org/10.1107/S2053230X14023589

Characterisation of a putative AraC transcriptional regulator from Mycobacterium smegmatis (2014)
Journal Article
Evangelopoulos, D., Gupta, A., Lack, N. A., Maitra, A., Ten Bokum, A. M. C., Kendall, S. L., …Bhakta, S. (2014). Characterisation of a putative AraC transcriptional regulator from Mycobacterium smegmatis. Tuberculosis, 94(6), 664-671. https://doi.org/10.1016/j.tube.2014.08.007

MSMEG_0307 is annotated as a transcriptional regulator belonging to the AraC protein family and is located adjacent to the arylamine N-acetyltransferase (nat) gene in Mycobacterium smegmatis, in a gene cluster, conserved in most environmental mycobac... Read More about Characterisation of a putative AraC transcriptional regulator from Mycobacterium smegmatis.

bkaR is a TetR-type repressor that controls an operon associated with branched chain keto-acid metabolism in mycobacteria (2013)
Journal Article
Balhana, R. J. C., Swanston, S. N., Coade, S., Withers, M., Sikder, M. H., Stoker, N. G., & Kendall, S. (2013). bkaR is a TetR-type repressor that controls an operon associated with branched chain keto-acid metabolism in mycobacteria. FEMS Microbiology Letters, 345(2), 132-40. https://doi.org/10.1111/1574-6968.12196

Bovine tuberculosis at the human-livestock-wildlife interface: is it a public health problem in Tanzania? A review. (2012)
Conference Proceeding
Katale, B. Z., Mbugi, E. V., Kendall, S. L., Fyumagwa, R. D., Kibiki, G. S. G. P., Keyyu, J. D., …Matee, M. I. (2012). Bovine tuberculosis at the human-livestock-wildlife interface: is it a public health problem in Tanzania? A review. https://doi.org/10.4102/ojvr.v79i2.463

The mycobacterial two-component regulatory systems (2005)
Book Chapter
Kendall, S. (2005). The mycobacterial two-component regulatory systems. . Norfolk, UK: Horizon Bioscience

Rison SCG, Kendall SL, Movahedzadeh F, Stoker NG.. In: Parish T, editor. Mycobacterium Molecular Microbiology.