Outputs (34)

Excessive growth hormone expression in male GH transgenic mice adversely alters bone architecture and mechanical strength (2015)
Journal Article
Lim, S., Marenzana, M., Hopkinson, M., List, E., Kopchick, J., Pereira, M., …Chenu, C. (2015). Excessive growth hormone expression in male GH transgenic mice adversely alters bone architecture and mechanical strength. Endocrinology, 156(4), 1362-1371. https://doi.org/10.1210/en.2014-1572

Patients with acromegaly have a higher prevalence of vertebral fractures despite normal bone mineral density (BMD), suggesting that GH overexpression has adverse effects on skeletal architecture and strength. We used giant bovine GH (bGH) transgenic... Read More about Excessive growth hormone expression in male GH transgenic mice adversely alters bone architecture and mechanical strength.

Low Dose of Propranolol Does Not Affect Rat Osteotomy Healing and Callus Strength (2014)
Journal Article
Smitham, P., Crossfield, L., Hughes, G., Goodship, A., Blunn, G., & Chenu, C. (2014). Low Dose of Propranolol Does Not Affect Rat Osteotomy Healing and Callus Strength. Journal of Orthopaedic Research, 32(7), 887-893. https://doi.org/10.1002/jor.22619

Experimental studies suggest that the β‐blocker propranolol stimulates bone formation but little work has investigated its effect on fracture healing. In this study, we examined if a low dose of propranolol, previously shown to be preventive against... Read More about Low Dose of Propranolol Does Not Affect Rat Osteotomy Healing and Callus Strength.

AMP-activated protein kinase (AMPK) activation regulates in vitro bone formation and bone mass
Journal Article
Shah, M., Kola, B., Bataveljic, A., Arnett, T. R., Viollet, B., Saxon, L., …Chenu, C. AMP-activated protein kinase (AMPK) activation regulates in vitro bone formation and bone mass. BONE, 47(2), 309-319. https://doi.org/10.1016/j.bone.2010.04.596

Neuropeptide Y expression and function during osteoblast differentiation - insights from transthyretin knockout mice
Journal Article
Nunes, A. F., Liz, M. A., Franquinho, F., Teixeira, L., Sousa, V., Chenu, C., …Sousa, M. M. Neuropeptide Y expression and function during osteoblast differentiation - insights from transthyretin knockout mice. FEBS Journal, 277(1), 263-275. https://doi.org/10.1111/j.1742-4658.2009.07482.x

DELETION OF AMP-ACTIVATED PROTEIN KINASE (AMPK)-ALPHA 1 CATALYTIC SUBUNIT IN MICE IMPAIRS THE IN VIVO RESPONSE OF BONES TO HORMONAL CHALLENGES
Journal Article
Shah, M., Viollet, B., Korbonits, M., & Chenu, C. DELETION OF AMP-ACTIVATED PROTEIN KINASE (AMPK)-ALPHA 1 CATALYTIC SUBUNIT IN MICE IMPAIRS THE IN VIVO RESPONSE OF BONES TO HORMONAL CHALLENGES. BONE, 48, S96-S96. https://doi.org/10.1016/j.bone.2011.03.139

DOES THE VASODILATORY ACTION OF PTH HELP ACCOUNT FOR ITS OSTEOGENIC EFFECTS?
Journal Article
Marenzana, M., Chenu, C., Pitsillides, A. A., & Arnett, T. R. DOES THE VASODILATORY ACTION OF PTH HELP ACCOUNT FOR ITS OSTEOGENIC EFFECTS?. BONE, 50, S160-S160. https://doi.org/10.1016/j.bone.2012.02.502

THE ANTI-DIABETIC DRUG METFORMIN HAS NO DELETERIOUS EFFECT ON BONE MASS IN VIVO BUT DOES NOT INDUCE OSTEOGENESIS NOR FRACTURE HEALING
Journal Article
Jeyabalan, J., Viollet, B., Smitham, P., Undre, Y., Ellis, S. A., Goodship, A., & Chenu, C. THE ANTI-DIABETIC DRUG METFORMIN HAS NO DELETERIOUS EFFECT ON BONE MASS IN VIVO BUT DOES NOT INDUCE OSTEOGENESIS NOR FRACTURE HEALING. Osteoporosis International, 23, S536-S536

Mice lacking AMP-activated protein kinase alpha 1 catalytic subunit have increased bone remodeling and modified skeletal responses to hormonal challenges induced by ovariectomy and intermittent PTH treatment.
Journal Article
Jeyabalan, J., Shah, M., Viollet, B., Roux, J. P., Chavassieux, P., Korbonits, M., & Chenu, C. Mice lacking AMP-activated protein kinase alpha 1 catalytic subunit have increased bone remodeling and modified skeletal responses to hormonal challenges induced by ovariectomy and intermittent PTH treatment. Journal of Endocrinology, 214(3), 349-358. https://doi.org/10.1530/JOE-12-0184

AMP-activated protein kinase pathway and bone metabolism
Journal Article
Jeyabalan, J., Shah, M., Viollet, B., & Chenu, C. AMP-activated protein kinase pathway and bone metabolism. Journal of Endocrinology, 212(3), 277-290. https://doi.org/10.1530/joe-11-0306

Mammalian Sulf1 RNA alternative splicing and its significance to tumour growth regulation
Journal Article
Gill, R. B. S., Day, A., Barstow, A., Zaman, G., Chenu, C., & Dhoot, G. K. Mammalian Sulf1 RNA alternative splicing and its significance to tumour growth regulation. https://doi.org/10.1007/s13277-012-0423-2