Outputs (83)

Muscle moment arms and sensitivity analysis of a mouse hindlimb musculoskeletal model
Journal Article
Charles, J. P., Cappellari, O., Spence, A. J., Wells, D. J., & Hutchinson, J. R. (in press). Muscle moment arms and sensitivity analysis of a mouse hindlimb musculoskeletal model. Journal of Anatomy, 229(4), 514-535. https://doi.org/10.1111/joa.12461

Histopathological Evaluation of Skeletal Muscle with Specific Reference to Mouse Models of Muscular Dystrophy
Journal Article
Terry, R. L., & Wells, D. J. Histopathological Evaluation of Skeletal Muscle with Specific Reference to Mouse Models of Muscular Dystrophy. https://doi.org/10.1002/cpmo.19

Olfaction variation in mouse husbandry and its implications for refinement and standardization: UK survey of animal scents
Journal Article
Lopez-Salesansky, N., Mazlan, N. H., Whitfield, L. E., Wells, D. J., & Burn, C. C. (in press). Olfaction variation in mouse husbandry and its implications for refinement and standardization: UK survey of animal scents. Laboratory Animals, 50(5), 362-369. https://doi.org/10.1177/0023677215622883

THE PHYSIOLOGICAL CONSEQUENCES OF DIFFERENT LEVELS OF DYSTROPHIN FOLLOWING ANTISENSE BASED EXON-SKIPPING IN THE MDX MOUSE
Journal Article
Muses, S., Godfrey, C., McClorey, G., Wells, K. E., Coursindel, T., Terry, R. L., …Wells, D. J. (in press). THE PHYSIOLOGICAL CONSEQUENCES OF DIFFERENT LEVELS OF DYSTROPHIN FOLLOWING ANTISENSE BASED EXON-SKIPPING IN THE MDX MOUSE. Neuromuscular Disorders, 25, S312-S313. https://doi.org/10.1016/j.nmd.2015.06.450

We examined the effects on muscle physiology of restoring different levels of dystrophin in mdx mice with established dystrophic pathophysiology (12 weeks and older). Dystrophin expression was induced very efficiently using cell penetrating peptides... Read More about THE PHYSIOLOGICAL CONSEQUENCES OF DIFFERENT LEVELS OF DYSTROPHIN FOLLOWING ANTISENSE BASED EXON-SKIPPING IN THE MDX MOUSE.

Implications for Cardiac Function Following Rescue of the Dystrophic Diaphragm in a Mouse Model of Duchenne Muscular Dystrophy
Journal Article
Betts, C. A., Saleh, A. F., Carr, C. A., Muses, S., Wells, K. E., Hammond, S. M., …Wood, M. J. A. (in press). Implications for Cardiac Function Following Rescue of the Dystrophic Diaphragm in a Mouse Model of Duchenne Muscular Dystrophy. https://doi.org/10.1038/srep11632

The TREAT-NMD advisory committee for therapeutics (TACT): an innovative de-risking model to foster orphan drug development
Journal Article
Heslop, E., Csimma, C., Straub, V., McCall, J., Nagaraju, K., Wagner, K. R., …Wells, D. J. (in press). The TREAT-NMD advisory committee for therapeutics (TACT): an innovative de-risking model to foster orphan drug development. Orphanet Journal of Rare Diseases, 10(49), https://doi.org/10.1186/s13023-015-0258-1

In silico characterisation and chromosomal localisation of human RRH (peropsin) – implications for opsin evolution
Journal Article
Bellingham, J., Wells, D. J., & Foster, R. G. In silico characterisation and chromosomal localisation of human RRH (peropsin) – implications for opsin evolution. BMC Genomics, 4(1), 3. https://doi.org/10.1186/1471-2164-4-3

RESTORING THE READING FRAME IN LARGE DMD DUPLICATION MUTATIONS RESULTS IN DYSTROPHIN EXPRESSION IN VIVO
Journal Article
Muses, S., Jones, H., & Wells, D. J. RESTORING THE READING FRAME IN LARGE DMD DUPLICATION MUTATIONS RESULTS IN DYSTROPHIN EXPRESSION IN VIVO. Neuromuscular Disorders, 22(9-10), 857-857. https://doi.org/10.1016/j.nmd.2012.06.181

IMPROVING TRANSLATIONAL STUDIES THROUGH BETTER ANIMAL EXPERIMENTS: LESSONS FROM THE HUMAN RARE DISEASE COMMUNITY
Journal Article
Wells, D. J. IMPROVING TRANSLATIONAL STUDIES THROUGH BETTER ANIMAL EXPERIMENTS: LESSONS FROM THE HUMAN RARE DISEASE COMMUNITY. Disease Models and Mechanisms,

Improving translational studies: lessons from rare neuromuscular diseases
Journal Article
Wells, D. J. Improving translational studies: lessons from rare neuromuscular diseases. Disease Models and Mechanisms, 8(10), 1175-7. https://doi.org/10.1242/dmm.022616