The Effect of Age on the Phenotype and Function of Developing Thymocytes
Journal Article
Aw, D. P. S., Silva, A. B., & Palmer, D. B. The Effect of Age on the Phenotype and Function of Developing Thymocytes. Journal of Comparative Pathology, 141, S45-S59. https://doi.org/10.1016/j.jcpa.2009.10.004
Outputs (33)
Early-life nutrition influences thymic growth in male mice that may be related to the regulation of longevity
Journal Article
Chen, J., Tarry-Adkins, J. L., Heppolette, C. A. A., Palmer, D. B., & Ozanne, S. E. Early-life nutrition influences thymic growth in male mice that may be related to the regulation of longevity. Clinical Science, 118(5-6), 429-38. https://doi.org/10.1042/CS20090429
Variation of human natural killer cell phenotypes with age: Identification of a unique KLRG1-negative subset
Journal Article
Hayhoe, R. P. G., Henson, S. M., Akbar, A. N., & Palmer, D. B. Variation of human natural killer cell phenotypes with age: Identification of a unique KLRG1-negative subset. Human Immunology, 71(7), 676-681. https://doi.org/10.1016/j.humimm.2010.03.014
BTN1A1, the Mammary Gland Butyrophilin, and BTN2A2 Are Both Inhibitors of T Cell Activation
Journal Article
Smith, I. A., Knezevic, B. R., Ammann, J. U., Rhodes, D. A., Aw, D., Palmer, D. B., …Trowsdale, J. BTN1A1, the Mammary Gland Butyrophilin, and BTN2A2 Are Both Inhibitors of T Cell Activation. Journal of Immunology, 184(7), 3514-3525. https://doi.org/10.4049/jimmunol.0900416
Is thymocyte development functional in the aged
Journal Article
Aw, D. P. S., Silva, A. B., & Palmer, D. B. Is thymocyte development functional in the aged
Phenotypical and morphological changes in the thymic microenvironment from ageing mice
Journal Article
Aw, D. P. S., Taylor-Brown, F. E., Cooper, K., & Palmer, D. B. Phenotypical and morphological changes in the thymic microenvironment from ageing mice. Biogerontology, 10(3), 311-322. https://doi.org/10.1007/s10522-008-9182-2
An evolutionary perspective on the mechanisms of immunosenescence
Journal Article
Shanley, D. P., Aw, D. P. S., Manley, N. R., & Palmer, D. B. An evolutionary perspective on the mechanisms of immunosenescence. Trends in Immunology, 30(7), 374-381. https://doi.org/10.1016/j.it.2009.05.001
Neuropeptides and thymic hormones in the Xenopus thymus
Journal Article
Silva, A. B., Aw, D. P. S., & Palmer, D. B. Neuropeptides and thymic hormones in the Xenopus thymus. Frontiers in Bioscience, 14, 1990-2003. https://doi.org/10.2741/3358T-cell development is characterised by a complex series of events in the thymus, which results in the development of self-restricted immunocompetent lymphocytes. We have previously reported the expression of neuropeptides in the thymus of various spe... Read More about Neuropeptides and thymic hormones in the Xenopus thymus.
Architectural changes in the thymus of aging mice
Journal Article
Aw, D. P. S., Silva, A. B., Maddick, M., von Zglinicki, T., & Palmer, D. B. Architectural changes in the thymus of aging mice. Aging Cell, 7(2), 158-167. https://doi.org/10.1111/j.1474-9726.2007.00365.xAge-associated thymic involution is one of the most dramatic and ubiquitous changes in the immune system, although the precise mechanisms involved still remain obscured. Several hypotheses have been proposed incorporating extrinsic and intrinsic fact... Read More about Architectural changes in the thymus of aging mice.
It's not all equal: a multiphasic theory of thymic involution
Journal Article
Aw, D. P. S., & Palmer, D. B. It's not all equal: a multiphasic theory of thymic involution. Biogerontology, 13(1), 77-81. https://doi.org/10.1007/s10522-011-9349-0