Outputs (2401)

Sost deficiency does not alter bone’s lacunar or vascular porosity in mice (2017)
Journal Article
Mosey, H., Núñez, J. A., Goring, A., Clarkin, C. E., Staines, K. A., Lee, P. D., …Javaheri, B. (2017). Sost deficiency does not alter bone’s lacunar or vascular porosity in mice. Frontiers in Materials, 4(27), https://doi.org/10.3389/fmats.2017.00027

SCLEROSTIN (Sost) is expressed predominantly in osteocytes acting as a negative regulator of bone formation. In humans, mutations in the SOST gene lead to skeletal overgrowth and increased bone mineral density, suggesting that SCLEROSTIN is a key reg... Read More about Sost deficiency does not alter bone’s lacunar or vascular porosity in mice.

Differential proteomic profiling of endometrium and plasma indicate the importance of hydrolysis in bovine endometritis (2017)
Journal Article
Zhang, S., Dong, S., Wang, D., Oguejiofor, C. F., Fouladi-Nashta, A. A., Yang, Z. Q., & Yan, Z. (2017). Differential proteomic profiling of endometrium and plasma indicate the importance of hydrolysis in bovine endometritis. Journal of Dairy Science, 100(11), 9324-9337. https://doi.org/10.3168/jds.2016-12365

Evaluation of analgesic effect and absorption of buprenorphine after buccal administration in cats with oral disease (2017)
Journal Article
Stathopoulou, T., Kouki, M., Pypendop, B. H., Johnston, A., Papadimitriou, S., & Pelligand, L. (2017). Evaluation of analgesic effect and absorption of buprenorphine after buccal administration in cats with oral disease. Journal of Feline Medicine and Surgery, 20(8), 704-710. https://doi.org/10.1177/1098612X17727234

Comparison of musculoskeletal networks of the primate forelimb (2017)
Journal Article
Molnar, J., Esteve-Altava, B., Rolian, C., & Diogo, R. (2017). Comparison of musculoskeletal networks of the primate forelimb. https://doi.org/10.1038/s41598-017-09566-7

Anatomical network analysis is a framework for quantitatively characterizing the topological organization of anatomical structures, thus providing a way to compare structural integration and modularity among species. Here we apply this approach to st... Read More about Comparison of musculoskeletal networks of the primate forelimb.

Reversible Keap1 inhibitors are preferential pharmacological tools to modulate cellular mitophagy (2017)
Journal Article
Georgakopoulos, N. D., Frison, M., Alvarez, M. S., Bertrand, H., Wells, G., & Campanella, M. (2017). Reversible Keap1 inhibitors are preferential pharmacological tools to modulate cellular mitophagy. https://doi.org/10.1038/s41598-017-07679-7

Mitophagy orchestrates the autophagic degradation of dysfunctional mitochondria preventing their pathological accumulation and contributing to cellular homeostasis. We previously identified a novel chemical tool (hereafter referred to as PMI), which... Read More about Reversible Keap1 inhibitors are preferential pharmacological tools to modulate cellular mitophagy.

Prolonging disuse in aged mice amplifies cortical but not trabecular bones’ response to mechanical loading (2017)
Journal Article
De Souza, R., Javaheri, B., Collinson, R. S., Chenu, C., Shefelbine, S., Lee, P. D., & Pitsillides, A. A. (2017). Prolonging disuse in aged mice amplifies cortical but not trabecular bones’ response to mechanical loading

Extracellular Vesicles: Evolutionarily Conserved Mediators of Intercellular Communication (2017)
Journal Article
Lawson, C., Kovacs, D., Finding, E. J. T., Ulfelder, E., & Fuentes, V. L. (2017). Extracellular Vesicles: Evolutionarily Conserved Mediators of Intercellular Communication

X Chromosome Evolution in Cetartiodactyla (2017)
Journal Article
Proskuryakova, A. A., Kulemzina, A. I., Perelman, P. L., Makunin, I. A., Larkin, D. M., Farré, M., …Graphodatsky, S. A. (2017). X Chromosome Evolution in Cetartiodactyla. Genes, 8(9), 216. https://doi.org/10.3390/genes8090216

The phenomenon of a remarkable conservation of the X chromosome in eutherian mammals has been first described by Susumu Ohno in 1964. A notable exception is the cetartiodactyl X chromosome, which varies widely in morphology and G-banding pattern betw... Read More about X Chromosome Evolution in Cetartiodactyla.

Elastin is Localised to the Interfascicular Matrix of Energy Storing Tendons and Becomes Increasingly Disorganised With Ageing (2017)
Journal Article
Godinho, M. S., Thorpe, C. T., Greenwald, S. E., & Screen, H. R. (2017). Elastin is Localised to the Interfascicular Matrix of Energy Storing Tendons and Becomes Increasingly Disorganised With Ageing. https://doi.org/10.1038/s41598-017-09995-4

Tendon is composed of fascicles bound together by the interfascicular matrix (IFM). Energy storing tendons are more elastic and extensible than positional tendons; behaviour provided by specialisation of the IFM to enable repeated interfascicular sli... Read More about Elastin is Localised to the Interfascicular Matrix of Energy Storing Tendons and Becomes Increasingly Disorganised With Ageing.

Hypercoagulability progresses to hypocoagulability during evolution of acetaminophen-induced acute liver injury in pigs (2017)
Journal Article
Lee, K. C. L., Baker, L., Mallett, S., Riddell, A., Chowdary, P., Alibhai, H. I. K., …Agarwal, B. (2017). Hypercoagulability progresses to hypocoagulability during evolution of acetaminophen-induced acute liver injury in pigs. https://doi.org/10.1038/s41598-017-09508-3

Increases in prothrombin time (PT) and international normalised ratio (INR) characterise acute liver injury (ALI) and failure (ALF), yet a wide heterogeneity in clotting abnormalities exists. This study defines evolution of coagulopathy in 10 pigs wi... Read More about Hypercoagulability progresses to hypocoagulability during evolution of acetaminophen-induced acute liver injury in pigs.