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Outputs (2401)

Transgenic Rescue of the LARGEmyd Mouse: A LARGE Therapeutic Window? (2016)
Journal Article
Hildyard, J. C. W., Lacey, E., Booler, H., Hopkinson, M., Wells, D. J., & Brown, S. C. (2016). Transgenic Rescue of the LARGEmyd Mouse: A LARGE Therapeutic Window?. PLoS ONE, 11(7), e0159853. https://doi.org/10.1371/journal.pone.0159853

LARGE is a glycosyltransferase involved in glycosylation of α-dystroglycan (α-DG). Absence of this protein in the LARGEmyd mouse results in α-DG hypoglycosylation, and is associated with central nervous system abnormalities and progressive muscular d... Read More about Transgenic Rescue of the LARGEmyd Mouse: A LARGE Therapeutic Window?.

The effect of the intracervical administration of follicle stimulating hormone or luteinizing hormone on the levels of hyaluronan, COX2 and COX2 mRNA in the cervix of the nonpregnant ewe (2016)
Journal Article
Leethongdee, S., Khalid, M., & Scaramuzzi, R. J. (2016). The effect of the intracervical administration of follicle stimulating hormone or luteinizing hormone on the levels of hyaluronan, COX2 and COX2 mRNA in the cervix of the nonpregnant ewe. Theriogenology, 86(9), 2244-2253. https://doi.org/10.1016/j.theriogenology.2016.07.014

Physiological, aerodynamic and geometric constraints of flapping account for bird gaits, and bounding and flap-gliding flight strategies (2016)
Journal Article
Usherwood, J. R. (2016). Physiological, aerodynamic and geometric constraints of flapping account for bird gaits, and bounding and flap-gliding flight strategies. Journal of Theoretical Biology, 408, 42-52. https://doi.org/10.1016/j.jtbi.2016.07.003

Aerodynamically economical flight is steady and level. The high-amplitude flapping and bounding flight style of many small birds departs considerably from any aerodynamic or purely mechanical optimum. Further, many large birds adopt a flap-glide flig... Read More about Physiological, aerodynamic and geometric constraints of flapping account for bird gaits, and bounding and flap-gliding flight strategies.

Degree of Cajal-Retzius cell mislocalisation correlates with the severity of structural brain defects in mouse models of dystroglycanopathy (2016)
Journal Article
Booler, H., Williams, J., Hopkinson, M., & Brown, S. C. (2016). Degree of Cajal-Retzius cell mislocalisation correlates with the severity of structural brain defects in mouse models of dystroglycanopathy. Brain Pathology, 26(4), 465-478. https://doi.org/10.1111/bpa.12306

The secondary dystroglycanopathies are characterized by the hypoglycosylation of alpha dystroglycan, and are associated with mutations in at least 18 genes that act on the glycosylation of this cell surface receptor rather than the Dag1 gene itself.... Read More about Degree of Cajal-Retzius cell mislocalisation correlates with the severity of structural brain defects in mouse models of dystroglycanopathy.

Neurodegeneration and Epilepsy in a Zebrafish Model of CLN3 Disease (Batten Disease) (2016)
Journal Article
Wager, K., Zdebik, A. A., Fu, S., Cooper, J. D., Harvey, R. J., & Russell, C. (2016). Neurodegeneration and Epilepsy in a Zebrafish Model of CLN3 Disease (Batten Disease). PLoS ONE, 11(6), https://doi.org/10.1371/journal.pone.0157365

The neuronal ceroid lipofuscinoses are a group of lysosomal storage disorders that comprise the most common, genetically heterogeneous, fatal neurodegenerative disorders of children. They are characterised by childhood onset, visual failure, epilepti... Read More about Neurodegeneration and Epilepsy in a Zebrafish Model of CLN3 Disease (Batten Disease).