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Musculoskeletal Geometry, Muscle Architecture and Functional Specialisations of the Mouse Hindlimb (2016)
Journal Article
Charles, J. P., Cappellari, O., Spence, A. J., Hutchinson, J. R., & Wells, D. J. (2016). Musculoskeletal Geometry, Muscle Architecture and Functional Specialisations of the Mouse Hindlimb. PLoS ONE, 11(4), https://doi.org/10.1371/journal.pone.0147669

Mice are one of the most commonly used laboratory animals, with an extensive array of disease models in existence, including for many neuromuscular diseases. The hindlimb is of particular interest due to several close muscle analogues/homologues to h... Read More about Musculoskeletal Geometry, Muscle Architecture and Functional Specialisations of the Mouse Hindlimb.

Combinatorial Analysis of Growth Factors Reveals the Contribution of Bone Morphogenetic Proteins to Chondrogenic Differentiation of Human Periosteal Cells (2016)
Journal Article
Mendes, L. F., Tam, W. L., Chai, Y. C., Geris, L., Luyten, F. P., & Roberts, S. J. (2016). Combinatorial Analysis of Growth Factors Reveals the Contribution of Bone Morphogenetic Proteins to Chondrogenic Differentiation of Human Periosteal Cells. https://doi.org/10.1089/ten.TEC.2015.0436

Successful application of cell-based strategies in cartilage and bone tissue engineering has been hampered by the lack of robust protocols to efficiently differentiate mesenchymal stem cells into the chondrogenic lineage. The development of chemicall... Read More about Combinatorial Analysis of Growth Factors Reveals the Contribution of Bone Morphogenetic Proteins to Chondrogenic Differentiation of Human Periosteal Cells.

Distribution of proteins within different compartments of tendon varies according to tendon type (2016)
Journal Article
Thorpe, C. T., Karunaseelan, K. J., Ng Chieng Hin, J., Riley, G. P., Birch, H. L., Clegg, P. D., & Screen, H. R. (2016). Distribution of proteins within different compartments of tendon varies according to tendon type. Journal of Anatomy, 229(3), 450-8. https://doi.org/10.1111/joa.12485

Although the predominant function of all tendons is to transfer force from muscle to bone and position the limbs, some tendons additionally function as energy stores, reducing the energetic cost of locomotion. To maximise energy storage and return, e... Read More about Distribution of proteins within different compartments of tendon varies according to tendon type.

The scaling of postcranial muscles in cats (Felidae) I: forelimb, cervical, and thoracic muscles (2016)
Journal Article
Cuff, A. R., Sparkes, E. L., Randau, M., Pierce, S. E., Kitchener, A. C., Goswami, A., & Hutchinson, J. R. (2016). The scaling of postcranial muscles in cats (Felidae) I: forelimb, cervical, and thoracic muscles. Journal of Anatomy, 229(1), 128-141. https://doi.org/10.1111/joa.12477

The body masses of cats (Mammalia, Carnivora, Felidae) span a ~300‐fold range from the smallest to largest species. Despite this range, felid musculoskeletal anatomy remains remarkably conservative, including the maintenance of a crouched limb postur... Read More about The scaling of postcranial muscles in cats (Felidae) I: forelimb, cervical, and thoracic muscles.

Temporal and phylogenetic evolution of the sauropod dinosaur body plan (2016)
Journal Article
Bates, K. T., Mannion, P. D., Falkingham, P. L., Brusatte, S. L., Hutchinson, J. R., Otero, A., …Allen, V. R. (2016). Temporal and phylogenetic evolution of the sauropod dinosaur body plan. Royal Society Open Science, 3(3), 150636. https://doi.org/10.1098/rsos.150636

The colossal size and body plan of sauropod dinosaurs are unparalleled in terrestrial vertebrates. However, to date, there have been only limited attempts to examine temporal and phylogenetic patterns in the sauropod bauplan. Here, we combine three-d... Read More about Temporal and phylogenetic evolution of the sauropod dinosaur body plan.