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CYP450-derived oxylipins mediate inflammatory resolution
Journal Article
Gilroy, D., Edin, M. L., Bystrom, J., Newson, J., Lih, F. B., Stables, M. L., …Bishop-Bailey, D. (in press). CYP450-derived oxylipins mediate inflammatory resolution. https://doi.org/10.1073/pnas.1521453113

Resolution of inflammation has emerged as an active process in immunobiology, with cells of the mononuclear phagocyte system being critical in mediating efferocytosis and wound debridement and bridging the gap between innate and adaptive immunity. He... Read More about CYP450-derived oxylipins mediate inflammatory resolution.

The nuclear receptor LXR modulates interleukin-18 levels through multiple mechanisms
Journal Article
Pourcet, B., Gage, M. C., Leon, T. E., Waddington, K. E., Pello, O. M., Steffensen, K. R., …Pineda-Torra, I. (in press). The nuclear receptor LXR modulates interleukin-18 levels through multiple mechanisms. https://doi.org/10.1038/srep25481

IL-18 is a member of the IL-1 family involved in innate immunity and inflammation. Deregulated levels of IL-18 are involved in the pathogenesis of multiple disorders including inflammatory and metabolic diseases, yet relatively little is known regard... Read More about The nuclear receptor LXR modulates interleukin-18 levels through multiple mechanisms.

Experimental type II diabetes and related models of impaired glucose metabolism differentially regulate glucose transporters at the proximal tubule brush border membrane
Journal Article
Chichger, H., Cleasby, M. E., Srai, S. K., Unwin, R. J., Debnam, E. S., & Marks, J. (in press). Experimental type II diabetes and related models of impaired glucose metabolism differentially regulate glucose transporters at the proximal tubule brush border membrane. Experimental Physiology, 101(6), 731-742. https://doi.org/10.1113/EP085670