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Supplementing a-Linolenic acid in the in vitro maturation media improves nuclear maturation rate of oocytes and early embryonic development in the Nili Ravi buffalo (2017)
Journal Article
Azam, A., Shahzad, Q., Ul-Husna, A., Qadee, S., Ejaz, R., Fouladi-Nashta, A. A., …Akhter, S. (2017). Supplementing a-Linolenic acid in the in vitro maturation media improves nuclear maturation rate of oocytes and early embryonic development in the Nili Ravi buffalo. Animal Reproduction Science, 14(4), 1161-119. https://doi.org/10.21451/1984-3143-AR859

The present study was conducted to investigate the effect of omega-3 poly unsaturated fatty acid (PUFA), α-linolenic acid (ALA; 18:3 n-3) on the in vitro maturation (IVM) of buffalo oocytes and subsequent embryonic development. Buffalo cumulusoocyte... Read More about Supplementing a-Linolenic acid in the in vitro maturation media improves nuclear maturation rate of oocytes and early embryonic development in the Nili Ravi buffalo.

Influence of hyaluronan on endometrial receptivity and embryo attachment in sheep (2017)
Journal Article
Marei, W. F. A., Wathes, D. C., Raheem, K. A., Mohey-Elsaeed, O., Ghafari, F., & Fouladi-Nashta, A. A. (2017). Influence of hyaluronan on endometrial receptivity and embryo attachment in sheep. https://doi.org/10.1071/RD16232

An increasing number of reports suggests a role of hyaluronan (HA) in female reproduction and interest in its application in assisted reproduction is rising. However, there are contrasting data about the effectiveness of adding HA to the embryo-trans... Read More about Influence of hyaluronan on endometrial receptivity and embryo attachment in sheep.

Clinical, pathological and functional characterization of riboflavin-responsive neuropathy (2017)
Journal Article
Manole, A., Jaunmuktane, Z., Hargreaves, I., Ludtmann, M. H. R., Pandraud, A., Salpietro, V., …Houlden, H. (2017). Clinical, pathological and functional characterization of riboflavin-responsive neuropathy. Brain, 140(11), 2820-2837. https://doi.org/10.1093/brain/awx231

Brown-Vialetto-Van Laere syndrome represents a phenotypic spectrum of motor, sensory, and cranial nerve neuropathy, often with ataxia, optic atrophy and respiratory problems leading to ventilator-dependence. Loss-of-function mutations in two riboflav... Read More about Clinical, pathological and functional characterization of riboflavin-responsive neuropathy.

Work minimization accounts for footfall phasing in slow quadrupedal gaits (2017)
Journal Article
Usherwood, J. R., & Self Davies, Z. T. (2017). Work minimization accounts for footfall phasing in slow quadrupedal gaits. eLife, 6, e29495. https://doi.org/10.7554/eLife.29495.001

Quadrupeds, like most bipeds, tend to walk with an even left/right footfall timing. However, the phasing between hind and forelimbs shows considerable variation. Here, we account for this variation by modeling and explaining the influence of hind-for... Read More about Work minimization accounts for footfall phasing in slow quadrupedal gaits.

Sost deficiency does not alter bone’s lacunar or vascular porosity in mice (2017)
Journal Article
Mosey, H., Núñez, J. A., Goring, A., Clarkin, C. E., Staines, K. A., Lee, P. D., …Javaheri, B. (2017). Sost deficiency does not alter bone’s lacunar or vascular porosity in mice. Frontiers in Materials, 4(27), https://doi.org/10.3389/fmats.2017.00027

SCLEROSTIN (Sost) is expressed predominantly in osteocytes acting as a negative regulator of bone formation. In humans, mutations in the SOST gene lead to skeletal overgrowth and increased bone mineral density, suggesting that SCLEROSTIN is a key reg... Read More about Sost deficiency does not alter bone’s lacunar or vascular porosity in mice.

Comparison of musculoskeletal networks of the primate forelimb (2017)
Journal Article
Molnar, J., Esteve-Altava, B., Rolian, C., & Diogo, R. (2017). Comparison of musculoskeletal networks of the primate forelimb. https://doi.org/10.1038/s41598-017-09566-7

Anatomical network analysis is a framework for quantitatively characterizing the topological organization of anatomical structures, thus providing a way to compare structural integration and modularity among species. Here we apply this approach to st... Read More about Comparison of musculoskeletal networks of the primate forelimb.

Reversible Keap1 inhibitors are preferential pharmacological tools to modulate cellular mitophagy (2017)
Journal Article
Georgakopoulos, N. D., Frison, M., Alvarez, M. S., Bertrand, H., Wells, G., & Campanella, M. (2017). Reversible Keap1 inhibitors are preferential pharmacological tools to modulate cellular mitophagy. https://doi.org/10.1038/s41598-017-07679-7

Mitophagy orchestrates the autophagic degradation of dysfunctional mitochondria preventing their pathological accumulation and contributing to cellular homeostasis. We previously identified a novel chemical tool (hereafter referred to as PMI), which... Read More about Reversible Keap1 inhibitors are preferential pharmacological tools to modulate cellular mitophagy.