Outputs (45)

Ornithine Phenylacetate targets alterations in the expression and activity of Glutamine Synthase and Glutaminase to reduce ammonia levels in bile duct ligated rats (2014)
Journal Article
Jover-Cobos, M., Noiret, L., Lee, K. C. L., Sharma, V., Habtesion, A., Romero-Gomez, M., …Jalan, R. (2014). Ornithine Phenylacetate targets alterations in the expression and activity of Glutamine Synthase and Glutaminase to reduce ammonia levels in bile duct ligated rats. Journal of Hepatology, 60(3), 545-553. https://doi.org/10.1016/j.jhep.2013.10.012

Background & Aims: In liver failure, ammonia homeostasis is dependent upon the function of the ammonia metabolising enzymes, glutamine synthetase (GS) and glutaminase (GA) but data about their protein expression and activity are lacking. The aims of... Read More about Ornithine Phenylacetate targets alterations in the expression and activity of Glutamine Synthase and Glutaminase to reduce ammonia levels in bile duct ligated rats.

A reproducible, clinically relevant, intensively managed, pig model of acute liver failure for testing of therapies aimed to prolong survival
Journal Article
Lee, K. C. L., Jimenez, C. P., Alibhai, H. I. K., Chang, Y. M., Leckie, P. J., Baker, L. A., …Davies, N. A. A reproducible, clinically relevant, intensively managed, pig model of acute liver failure for testing of therapies aimed to prolong survival. Liver International, 33(4), 544-551. https://doi.org/10.1111/liv.12042

INCREASE IN PLASMA MICRORNA POOL AND GENOMIC DNA LEVELS IN AN ACETAMINOPHEN-INDUCED PORCINE MODEL OF ACUTE LIVER FAILURE: A KINETIC STUDY
Journal Article
Baker, L. A., Andreola, F., Lee, K. C. L., Jimenez, C. P., Chang, Y. M., Alibhai, H. I. K., …Jalan, R. INCREASE IN PLASMA MICRORNA POOL AND GENOMIC DNA LEVELS IN AN ACETAMINOPHEN-INDUCED PORCINE MODEL OF ACUTE LIVER FAILURE: A KINETIC STUDY. Hepatology, 58, 357A-358A

INTERACTIONS BETWEEN ESTROGEN AND GLUTAMATE SIGNALLING PATHWAYS
Journal Article
Odoi, S. O., Taylor, A. F., Lee, K. C. L., Lanyon, L., & Skerry, T. INTERACTIONS BETWEEN ESTROGEN AND GLUTAMATE SIGNALLING PATHWAYS. Journal of Bone and Mineral Research, 17(7), 1331-1331

LONGITUDINAL STUDIES OF COAGULATION PROFILE IN THE SYSTEMIC AND PORTAL CIRCULATIONS IN A PORCINE MODEL OF ACETAMINOPHEN INDUCED ACUTE LIVER FAILURE SHOW THAT A HYPERCOAGUABLE STATE PRECEDES A HYPOCOAGUABLE STATE AND IS ASSOCIATED WITH ENDOTOXAEMIA
Journal Article
Lee, K. C. L., Baker, L., Mallett, S., Riddell, A., Giordano, P., Leckie, P., …Jalan, R. LONGITUDINAL STUDIES OF COAGULATION PROFILE IN THE SYSTEMIC AND PORTAL CIRCULATIONS IN A PORCINE MODEL OF ACETAMINOPHEN INDUCED ACUTE LIVER FAILURE SHOW THAT A HYPERCOAGUABLE STATE PRECEDES A HYPOCOAGUABLE STATE AND IS ASSOCIATED WITH ENDOTOXAEMIA. Hepatology, 58, 348A-349A

A REPRODUCIBLE, CLINICALLY-RELEVANT, INTENSIVELY-MANAGED, PIG MODEL OF ACUTE LIVER FAILURE FOR TESTING OF THERAPIES AIMED TO PROLONG SURVIVAL
Journal Article
Lee, K. C. L., Palacios, C. J., Alibhai, H. I. K., Chang, Y. M., Leckie, P., Priestnall, S. L., …Davies, N. A REPRODUCIBLE, CLINICALLY-RELEVANT, INTENSIVELY-MANAGED, PIG MODEL OF ACUTE LIVER FAILURE FOR TESTING OF THERAPIES AIMED TO PROLONG SURVIVAL. Journal of Hepatology, 56, S102-S102

A REPRODUCIBLE, CLINICALLY-RELEVANT, INTENSIVELY-MANAGED, PIG MODEL OF ACUTE LIVER FAILURE FOR TESTING OF THERAPIES AIMED TO PROLONG SURVIVAL
Journal Article
Lee, K. C. L., Palacios, C. J., Alibhai, H. I. K., Chang, Y. M., Leckie, P., Priestnall, S. L., …Davies, N. A REPRODUCIBLE, CLINICALLY-RELEVANT, INTENSIVELY-MANAGED, PIG MODEL OF ACUTE LIVER FAILURE FOR TESTING OF THERAPIES AIMED TO PROLONG SURVIVAL. Gut, 61, A186-A186. https://doi.org/10.1136/gutjnl-2012-302514c.8

Clinical outcome following pneumonectomy for management of chronic pyothorax in four cats
Journal Article
Crawford, A. H., Halfacree, Z. J., Lee, K. C. L., & Brockman, D. J. Clinical outcome following pneumonectomy for management of chronic pyothorax in four cats. Journal of Feline Medicine and Surgery, 13(10), 762-767. https://doi.org/10.1016/j.jfms.2011.03.004

Radial Artery Pseudoaneurysm in a Maine Coon Cat
Journal Article
Hall, J. L., Lee, K. C. L., Priestnall, S. L., & Lamb, C. R. Radial Artery Pseudoaneurysm in a Maine Coon Cat. Veterinary Surgery, 40(7), 861-864. https://doi.org/10.1111/j.1532-950X.2011.00868.x

Prevalence, outcome and risk factors for postoperative pyothorax in 232 dogs undergoing thoracic surgery
Journal Article
Meakin, L. B., Salonen, L. K., Baines, S. J., Brockman, D. J., Gregory, S. P., Halfacree, Z. J., …Lee, K. C. L. Prevalence, outcome and risk factors for postoperative pyothorax in 232 dogs undergoing thoracic surgery. Journal of Small Animal Practice, 54(6), 313-7. https://doi.org/10.1111/jsap.12064