Outputs (78)

Storage-associated artefact in equine muscle biopsy samples
Journal Article
Stanley, R. L., Maile, C., & Piercy, R. J. Storage-associated artefact in equine muscle biopsy samples. Equine Veterinary Journal, 41(1), 82-86. https://doi.org/10.2746/042516408x330374

Reasons for performing study: Muscle biopsy is increasingly used in equine veterinary practice for investigating exertional, inflammatory or immune mediated myopathies and unexplained muscle atrophy. Although formalin-fixed samples are often used, fo... Read More about Storage-associated artefact in equine muscle biopsy samples.

A glycogen synthase 1 mutation associated with equine polysaccharide storage myopathy and exertional rhabdomyolysis occurs in a variety of UK breeds
Journal Article
Stanley, R. L., McCue, M. E., Valberg, S. J., Mickelson, J. R., Mayhew, I. G., McGowan, C., …Piercy, R. J. A glycogen synthase 1 mutation associated with equine polysaccharide storage myopathy and exertional rhabdomyolysis occurs in a variety of UK breeds. Equine Veterinary Journal, 41(6), 597-601. https://doi.org/10.2746/042516409x407611

Heritability of Recurrent Exertional Rhabdomyolysis in Standardbred and Thoroughbred Racehorses Derived From SNP Genotyping Data
Journal Article
Norton, E. M., Mickelson, J. R., Binns, M. M., Blott, S. C., Caputo, P., Isgren, C. M., …McCue, M. E. (in press). Heritability of Recurrent Exertional Rhabdomyolysis in Standardbred and Thoroughbred Racehorses Derived From SNP Genotyping Data. Journal of Heredity, 107(6), 537-43. https://doi.org/10.1093/jhered/esw042

Equine atypical myopathy in the UK: Epidemiological characteristics of cases reported from 2011 to 2015 and factors associated with survival
Journal Article
González-Medina, S., Ireland, J. L., Piercy, R. J., Newton, J. R., & Votion, D. M. (in press). Equine atypical myopathy in the UK: Epidemiological characteristics of cases reported from 2011 to 2015 and factors associated with survival. Equine Veterinary Journal, 49(6), 746-752. https://doi.org/10.1111/evj.12694

Disease severity in dominant Emery Dreifuss is increased by mutations in both emerin and desmin proteins
Journal Article
Muntoni, F., Bonne, G., Goldfarb, L. G., Mercuri, E., Piercy, R. J., Burke, M., …Brown, S. C. Disease severity in dominant Emery Dreifuss is increased by mutations in both emerin and desmin proteins. Brain, 129, 1260-1268. https://doi.org/10.1093/brain/awl062

Cerebrospinal fluid collection and its analysis in equine neurological disease
Journal Article
Schwarz, B. C., & Piercy, R. J. Cerebrospinal fluid collection and its analysis in equine neurological disease. Equine Veterinary Education, 18(5), 243-248

Extreme variability of skeletal and cardiac muscle involvement in patients with mutations in exon 11 of the lamin A/C gene
Journal Article
Mercuri, E., Brown, S. C., Nihoyannopoulos, P., Poulton, J., Kinali, M., Richard, P., …Muntoni, F. Extreme variability of skeletal and cardiac muscle involvement in patients with mutations in exon 11 of the lamin A/C gene. Muscle & Nerve, 31(5), 602-609. https://doi.org/10.1002/mus.20293

Biochemical and genetic evaluation of the role of AMP-activated protein kinase in polysaccharide storage myopathy in Quarter Horses
Journal Article
Dranchak, P. K., Leiper, F. C., Valberg, S. J., Piercy, R. J., Carling, D., McCue, M. E., & Mickelson, J. R. Biochemical and genetic evaluation of the role of AMP-activated protein kinase in polysaccharide storage myopathy in Quarter Horses. American Journal of Veterinary Research, 68(10), 1079-1084. https://doi.org/10.2460/ajvr.68.10.1079

Investigating the pathology of Emery-Dreifuss muscular dystrophy
Journal Article
Brown, S. C., Piercy, R. J., Muntoni, F., & Sewry, C. A. Investigating the pathology of Emery-Dreifuss muscular dystrophy. Biochemical Society Transactions, 36(Pt 6), 1335-1338. https://doi.org/10.1042/bst0361335

EDMD (Emery-Dreifuss muscular dystrophy) is caused by mutations in either the gene encoding for lamin A/C (LMNA) located at 1q21.2-q21.3 of emerin (EMD) located at Xq28. Autosomal dominant EDMD caused by LMNA mutations is more common than the X-linke... Read More about Investigating the pathology of Emery-Dreifuss muscular dystrophy.

Assessment of the transformation of equine skin-derived fibroblasts to multinucleated skeletal myotubes following lentiviral-induced expression of equine myogenic differentiation 1
Journal Article
Fernandez-Fuente, M., Ames, E. G., Wagner, M. L., Zhou, H., Strom, M., Zammit, P. S., …Piercy, R. J. Assessment of the transformation of equine skin-derived fibroblasts to multinucleated skeletal myotubes following lentiviral-induced expression of equine myogenic differentiation 1. American Journal of Veterinary Research, 69(12), 1637-1645. https://doi.org/10.2460/ajvr.69.12.1637

Objective - To develop a reliable method for converting cultured equine skin-derived fibroblasts into muscle cells. Sample Population - Equine skin-derived fibroblasts. Procedures - The equine myogenic differentiation 1 (eqMyoD) genomic sequence was... Read More about Assessment of the transformation of equine skin-derived fibroblasts to multinucleated skeletal myotubes following lentiviral-induced expression of equine myogenic differentiation 1.