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Outputs (3013)

Semi-Mechanistic Modeling of Florfenicol Time-Kill Curves and in silico Dose Fractionation for Calf Respiratory Pathogens (2019)
Journal Article
Pelligand, L., Lees, P., Sidhu, P. K., & Toutain, P. (2019). Semi-Mechanistic Modeling of Florfenicol Time-Kill Curves and in silico Dose Fractionation for Calf Respiratory Pathogens. Frontiers in Microbiology, 10, https://doi.org/10.3389/fmicb.2019.01237

An important application of time-kill curve (TKC) assays is determination of the nature of the best PK/PD index (fAUC/MIC or fT% > MIC) and its target value for predicting clinical efficacy in vivo. VetCAST (the veterinary subcommittee of EUCAST) her... Read More about Semi-Mechanistic Modeling of Florfenicol Time-Kill Curves and in silico Dose Fractionation for Calf Respiratory Pathogens.

Indoleamine-pyrrole 2,3-dioxygenase-1 (IDO-1) mRNA is over-expressed in the duodenal mucosa and is negatively correlated with serum tryptophan concentrations in dogs with protein-losing enteropathy (2019)
Journal Article
Kathrani, A., Lezcano, V., Hall, E. J., Jergens, A. E., Seo, Y., Mochel, J. P., …Allenspach, K. (2019). Indoleamine-pyrrole 2,3-dioxygenase-1 (IDO-1) mRNA is over-expressed in the duodenal mucosa and is negatively correlated with serum tryptophan concentrations in dogs with protein-losing enteropathy. PLoS ONE, 14(6), e0218218. https://doi.org/10.1371/journal.pone.0218218

Prevalence of and risk factors for acute laminitis in horses treated with corticosteroids (2019)
Journal Article
Potter, K., Stevens, K. B., & Menzies-Gow, N. J. (2019). Prevalence of and risk factors for acute laminitis in horses treated with corticosteroids. Veterinary Record, 85(82), https://doi.org/10.1136/vr.105378

A retrospective treated versus untreated study (study 1) and multicentre prospective cohort study (study 2) were undertaken to determine the prevalence of, and risk factors associated with, acute laminitis in horses treated with corticosteroids. All... Read More about Prevalence of and risk factors for acute laminitis in horses treated with corticosteroids.

Exploring early life events including diet in cats presenting for gastrointestinal signs in later life (2019)
Journal Article
Kathrani, A., Blackwell, E. J., Williams, J. L., Gruffydd-Jones, T. J., Murray, J. K., Hezzell, M., & Hall, E. J. (2019). Exploring early life events including diet in cats presenting for gastrointestinal signs in later life. Veterinary Record, https://doi.org/10.1136/vr.105040

Our study aimed to determine if certain early life events were more prevalent in cats presenting to veterinary practices specifically for gastrointestinal signs on at least two occasions between six months and 30 months of age. Data from an owner-com... Read More about Exploring early life events including diet in cats presenting for gastrointestinal signs in later life.

VEGF with AMD3100 Endogenously Mobilizes Mesenchymal Stem Cells and Improves Fracture Healing (2019)
Journal Article
Meeson, R. L., Sanghani-Keri, A., Coathup, M., & Blunn, G. (2019). VEGF with AMD3100 Endogenously Mobilizes Mesenchymal Stem Cells and Improves Fracture Healing. Journal of Orthopaedic Research, 37(6), 1294-1302. https://doi.org/10.1002/jor.24164

A significant number of fractures develop non‐union. Mesenchymal stem cell (MSC) therapy may be beneficial, however, this requires cell acquisition, culture and delivery. Endogenous mobilization of stem cells offers a non‐invasive alternative. The hy... Read More about VEGF with AMD3100 Endogenously Mobilizes Mesenchymal Stem Cells and Improves Fracture Healing.

A cross-sectional study of horse owners’ awareness and perceived risk of exotic diseases in the United Kingdom (2019)
Journal Article
Spence, K. L., Slater, J. D., Rosanowski, S. M., & Cardwell, J. M. (2019). A cross-sectional study of horse owners’ awareness and perceived risk of exotic diseases in the United Kingdom. Preventive Veterinary Medicine, https://doi.org/10.1016/j.prevetmed.2019.104706

The international nature of the equine industry provides opportunities for the spread of infectious diseases between countries. While incursions of exotic diseases into the United Kingdom (UK) equine population have been rare, the potential socioecon... Read More about A cross-sectional study of horse owners’ awareness and perceived risk of exotic diseases in the United Kingdom.