Pathobiology and Population Sciences

Single Nucleotide Polymorphisms in Major histocompatibility class II haplotypes are associated with potential resistance to inflammatory bowel disease in German shepherd dogs (2016)
Journal Article
Peiravan, A., Allenspach, K., Boag, A. M., Soutter, F., Holder, A. L., Catchpole, B., …Procoli, F. (2016). Single Nucleotide Polymorphisms in Major histocompatibility class II haplotypes are associated with potential resistance to inflammatory bowel disease in German shepherd dogs. Veterinary Immunology and Immunopathology, 182, 101-105. https://doi.org/10.1016/j.vetimm.2016.10.012

The efficacy of alcelaphine herpesvirus-1 (AlHV-1) immunization with the adjuvants Emulsigen® and the monomeric TLR5 ligand FliC in zebu cattle against AlHV-1 malignant catarrhal fever induced by experimental virus challenge (2016)
Journal Article
Lankester, F., Lugelo, A., Werling, D., Mnyambwa, N., Keyyu, J., Kazwala, R., …Haig, D. (2016). The efficacy of alcelaphine herpesvirus-1 (AlHV-1) immunization with the adjuvants Emulsigen® and the monomeric TLR5 ligand FliC in zebu cattle against AlHV-1 malignant catarrhal fever induced by experimental virus challenge. Veterinary Microbiology, 195, 144-153. https://doi.org/10.1016/j.vetmic.2016.09.019

Identification of Theileria lestoquardi Antigens Recognized by CD8+ T Cells (2016)
Journal Article
Goh, S., Ngugi, D., Lizundia, R., Hostettler, I., Woods, K., Ballingall, K., …Werling, D. (2016). Identification of Theileria lestoquardi Antigens Recognized by CD8+ T Cells. PLoS ONE, 11(9), e0162571. https://doi.org/10.1371/journal.pone.0162571

Oral application of freeze-dried yeast particles expressing the PCV2b Cap protein on their surface induce protection to subsequent PCV2b challenge in vivo (2015)
Journal Article
Patterson, R., Eley, T. S., Browne, C., Martineau, H. M., & Werling, D. (2015). Oral application of freeze-dried yeast particles expressing the PCV2b Cap protein on their surface induce protection to subsequent PCV2b challenge in vivo. Vaccine, 33(46), 6199-205. https://doi.org/10.1016/j.vaccine.2015.10.003

Porcine circovirus type 2 (PCV2) is now endemic in every major pig producing country, causing PCV-associated disease (PCVAD), linked with large scale economic losses. Current vaccination strategies are based on the capsid protein of the virus and are... Read More about Oral application of freeze-dried yeast particles expressing the PCV2b Cap protein on their surface induce protection to subsequent PCV2b challenge in vivo.

Combining Genome Wide Association Studies and Differential Gene Expression Data Analyses Identifies Candidate Genes Affecting Mastitis Caused by Two Different Pathogens in the Dairy Cow (2015)
Journal Article
Chen, X., Cheng, Z. R., Zhang, S., Werling, D., & Wathes, D. C. (2015). Combining Genome Wide Association Studies and Differential Gene Expression Data Analyses Identifies Candidate Genes Affecting Mastitis Caused by Two Different Pathogens in the Dairy Cow. Open Journal of Animal Sciences, 5(4), 358-393. https://doi.org/10.4236/ojas.2015.54040

Mastitis is a costly disease which hampers the dairy industry. Inflammation of the mammary gland is commonly caused by bacterial infection, mainly Escherichia coli, Streptococcus uberis and Staphylococcus aureus. As more bacteria become multi-drug re... Read More about Combining Genome Wide Association Studies and Differential Gene Expression Data Analyses Identifies Candidate Genes Affecting Mastitis Caused by Two Different Pathogens in the Dairy Cow.

Exposure to environmental stressors result in increased viral load and further reduction of production parameters in pigs experimentally infected with PCV2b (2015)
Journal Article
Patterson, R., Nevel, M., Diaz, A. V., Martineau, H. M., Demmers, T. G. M., Browne, C., …Werling, D. (2015). Exposure to environmental stressors result in increased viral load and further reduction of production parameters in pigs experimentally infected with PCV2b. Veterinary Microbiology, 177(3-4), 261-269. https://doi.org/10.1016/j.vetmic.2015.03.010

Porcine circovirus type 2 (PCV2) has been identified as the essential, but not sole, underlying infectious component for PCV-associated diseases (PCVAD). Several co-factors have been suggested to convert an infection with PCV2 into the clinical signs... Read More about Exposure to environmental stressors result in increased viral load and further reduction of production parameters in pigs experimentally infected with PCV2b.

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