Outputs (17)

Avian influenza viruses in wild birds: virus evolution in a multi-host ecosystem (2018)
Journal Article
Venkatesh, D., Poen, M. J., Bestebroer, T. M., Scheuer, R. D., Vuong, O., Chkhaidze, M., …Lewis, N. S. (2018). Avian influenza viruses in wild birds: virus evolution in a multi-host ecosystem. Journal of Virology, 92, https://doi.org/10.1128/JVI.00433-18

Wild ducks and gulls are the major reservoirs for avian influenza A viruses (AIVs). The mechanisms that drive AIV evolution are complex at sites where various duck and gull species from multiple flyways breed, winter, or stage. The Republic of Georgi... Read More about Avian influenza viruses in wild birds: virus evolution in a multi-host ecosystem.

Antigenic and genetic evolution of contemporary swine H1 influenza viruses in the United States (2018)
Journal Article
Rajao, D. S., Anderson, T. K., Kitikoon, P., Stratton, J., Lewis, N. S., & Vincent, A. L. (2018). Antigenic and genetic evolution of contemporary swine H1 influenza viruses in the United States. Virology, 518, 45-54. https://doi.org/10.1016/j.virol.2018.02.006

Several lineages of influenza A viruses (IAV) currently circulate in North American pigs. Genetic diversity is further increased by transmission of IAV between swine and humans and subsequent evolution. Here, we characterized the genetic and antigeni... Read More about Antigenic and genetic evolution of contemporary swine H1 influenza viruses in the United States.

The global antigenic diversity of swine influenza A viruses (2016)
Journal Article
Lewis, N. S., Russell, C. A., Langat, P., Anderson, T. K., Berger, K., Bielejec, F., …Vincent, A. L. (2016). The global antigenic diversity of swine influenza A viruses. eLife, 5, e12217. https://doi.org/10.7554/eLife.12217

wine influenza presents a substantial disease burden for pig populations worldwide and poses a potential pandemic threat to humans. There is considerable diversity in both H1 and H3 influenza viruses circulating in swine due to the frequent introduct... Read More about The global antigenic diversity of swine influenza A viruses.

Novel Reassortant Human-Like H3N2 and H3N1 Influenza A Viruses Detected in Pigs Are Virulent and Antigenically Distinct from Swine Viruses Endemic to the United States (2015)
Journal Article
Rajão, D. S., Gauger, P. C., Anderson, T. K., Lewis, N. S., Abente, E. J., Killian, M. L., …Vincent, A. L. (2015). Novel Reassortant Human-Like H3N2 and H3N1 Influenza A Viruses Detected in Pigs Are Virulent and Antigenically Distinct from Swine Viruses Endemic to the United States. Journal of Virology, 89(22), 11213-22. https://doi.org/10.1128/JVI.01675-15

Influenza A virus evolution and spatio-temporal dynamics in Eurasian wild birds: a phylogenetic and phylogeographical study of whole-genome sequence data (2015)
Journal Article
Lewis, N. S., Verhagen, J. H., Javakhishvili, Z., Russell, C. A., Lexmond, P., Westgeest, K. B., …De Graaf, M. (2015). Influenza A virus evolution and spatio-temporal dynamics in Eurasian wild birds: a phylogenetic and phylogeographical study of whole-genome sequence data. Journal of General Virology, 96(8), 2050-60. https://doi.org/10.1099/vir.0.000155

Low pathogenic avian influenza A viruses (IAVs) have a natural host reservoir in wild waterbirds and the potential to spread to other host species. Here, we investigated the evolutionary, spatial and temporal dynamics of avian IAVs in Eurasian wild b... Read More about Influenza A virus evolution and spatio-temporal dynamics in Eurasian wild birds: a phylogenetic and phylogeographical study of whole-genome sequence data.

Substitutions near the hemagglutinin receptor-binding site determine the antigenic evolution of influenza A H3N2 viruses in U.S. swine (2014)
Journal Article
Lewis, N. S., Anderson, T. K., Kitikoon, P., Skepner, E., Burke, D. F., & Vincent, A. L. (2014). Substitutions near the hemagglutinin receptor-binding site determine the antigenic evolution of influenza A H3N2 viruses in U.S. swine. Journal of Virology, 88(9), 4752-63. https://doi.org/10.1128/JVI.03805-13

Swine influenza A virus is an endemic and economically important pathogen in pigs, with the potential to infect other host species. The hemagglutinin (HA) protein is the primary target of protective immune responses and the major component in swine i... Read More about Substitutions near the hemagglutinin receptor-binding site determine the antigenic evolution of influenza A H3N2 viruses in U.S. swine.

Intercontinental spread of Asian-origin H7 avian influenza viruses by captive bird trade in 1990's
Journal Article
Lee, D., Killian, M. L., Torchetti, M. K., Brown, I., Lewis, N. S., Berhane, Y., & Swayne, D. E. (in press). Intercontinental spread of Asian-origin H7 avian influenza viruses by captive bird trade in 1990's. https://doi.org/10.1016/j.meegid.2019.04.028

Wild bird migration and illegal trade of infected poultry, eggs, and poultry products have been associated with the spread of avian influenza viruses (AIV). During 1992–1996, H7N1 and H7N8 low pathogenic AIV (LPAIV) were identified from captive wild... Read More about Intercontinental spread of Asian-origin H7 avian influenza viruses by captive bird trade in 1990's.