Regulation of UDP-Glucose Dehydrogenase Is Sufficient to Modulate Hyaluronan Production and Release, Control Sulfated GAG Synthesis, and Promote Chondrogenesis
Journal Article
Clarkin, C. E., Allen, S., Kuiper, N. J., Wheeler, B. T., Wheeler-Jones, C. P. D., & Pitsillides, A. A. Regulation of UDP-Glucose Dehydrogenase Is Sufficient to Modulate Hyaluronan Production and Release, Control Sulfated GAG Synthesis, and Promote Chondrogenesis. Journal of Cellular Physiology, 226(3), 749-761. https://doi.org/10.1002/jcp.22393
All Outputs (100)
Reduced chondrogenic matrix accumulation by 4-methylumbelliferone reveals the potential for selective targeting of UDP-glucose dehydrogenase
Journal Article
Clarkin, C. E., Allen, S. P., Wheeler-Jones, C. P. D., Bastow, E. R., & Pitsillides, A. A. Reduced chondrogenic matrix accumulation by 4-methylumbelliferone reveals the potential for selective targeting of UDP-glucose dehydrogenase. Matrix Biology, 30(3), 163-168. https://doi.org/10.1016/j.matbio.2011.01.002
Influence of chylomicron remnants on human monocyte activation in vitro.
Journal Article
Bentley, C., Hathaway, N., Widdows, J., Bejta, F., De Pascale, C., Avella, M. A., …Lawson, C. Influence of chylomicron remnants on human monocyte activation in vitro. https://doi.org/10.1016/j.numecd.2010.02.019
A NATURALLY OCCURRING MODEL OF LIVER REGENERATION? CHANGES IN MRNA EXPRESSION OF MARKERS OF HEPATIC REGENERATION IN LIVER TISSUE FROM DOGS WITH CONGENITAL PORTOSYSTEMIC SHUNTS FOLLOWING PARTIAL ATTENUATION
Journal Article
Tivers, M. S., Lipscomb, V. J., Smith, K. C., Wheeler-Jones, C. P. D., & House, A. K. A NATURALLY OCCURRING MODEL OF LIVER REGENERATION? CHANGES IN MRNA EXPRESSION OF MARKERS OF HEPATIC REGENERATION IN LIVER TISSUE FROM DOGS WITH CONGENITAL PORTOSYSTEMIC SHUNTS FOLLOWING PARTIAL ATTENUATION. Gut, 61, A127-A127. https://doi.org/10.1136/gutjnl-2012-302514b.133
Expression of guanylyl cyclase-B (GC-B/NPR2) receptors in normal human fetal pituitaries and human pituitary adenomas implicates a regulatory role for C-type natriuretic peptide
Journal Article
Thompson, I. R., Chand, A. N., King, P. J., Ansorge, O., Karavitaki, N., Jones, C. A., …Fowkes, R. C. Expression of guanylyl cyclase-B (GC-B/NPR2) receptors in normal human fetal pituitaries and human pituitary adenomas implicates a regulatory role for C-type natriuretic peptide. Endocrine-Related Cancer, 19(4), 497-508. https://doi.org/10.1530/ERC-12-0129
Mechanical strain and estrogen activate estrogen receptor alpha in bone cells
Journal Article
Jessop, H. L., Sjoberg, M., Cheng, M. Z., Zaman, G., Wheeler-Jones, C. P. D., & Lanyon, L. E. Mechanical strain and estrogen activate estrogen receptor alpha in bone cells. Journal of Bone and Mineral Research, 16(6), 1045-1055. https://doi.org/10.1359/jbmr.2001.16.6.1045
Requirement for ERK1/2 activation in the regulation of progesterone production in human granulosa-lutein cells is stimulus specific
Journal Article
Dewi, D. A., Abayasekara, D. R. E., & Wheeler-Jones, C. P. D. Requirement for ERK1/2 activation in the regulation of progesterone production in human granulosa-lutein cells is stimulus specific. Endocrinology, 143(3), 877-888. https://doi.org/10.1210/en.143.3.877
Protease-activated receptors upregulate cyclooxygenase-2 expression in human endothelial cells
Journal Article
Houliston, R. A., Keogh, R. J., Sugden, D., Dudhia, J., Carter, T. D., & Wheeler-Jones, C. P. D. Protease-activated receptors upregulate cyclooxygenase-2 expression in human endothelial cells. Thrombosis and Haemostasis, 88(2), 321-28
Cytokine upregulation of proteinase-activated-receptors 2 and 4 expression mediated by p38 MAP kinase and inhibitory kappa B kinase beta in human endothelial cells
Journal Article
Ritchie, E., Saka, M., MacKenzie, C., Drummond, R., Wheeler-Jones, C. P. D., Kanke, T., & Plevin, R. Cytokine upregulation of proteinase-activated-receptors 2 and 4 expression mediated by p38 MAP kinase and inhibitory kappa B kinase beta in human endothelial cells. British Journal of Pharmacology, 150(8), 1044-1054. https://doi.org/10.1038/sj.bjp.0707150
Differential exocytosis from human endothelial cells evoked by high intracellular Ca2+ concentration
Journal Article
Zupancic, G., Ogden, D., Magnus, C. J., Wheeler-Jones, C. P. D., & Carter, T. D. Differential exocytosis from human endothelial cells evoked by high intracellular Ca2+ concentration. Journal of Physiology, 544(3), 741-755. https://doi.org/10.1113/jphysiol.2002.027490
Early activation of the p42/p44(MAPK) pathway mediates adenosine-induced nitric oxide production in human endothelial cells: a novel calcium-insensitive mechanism
Journal Article
Wyatt, A. W., Steinert, J. R., Wheeler-Jones, C. P. D., Morgan, A. J., Sugden, D., Pearson, J. D., …Mann, G. E. Early activation of the p42/p44(MAPK) pathway mediates adenosine-induced nitric oxide production in human endothelial cells: a novel calcium-insensitive mechanism. FASEB Journal, 16(12), 1584-1594. https://doi.org/10.1096/fj.01-0125com
A key role for beta-cell cytosolic phospholipase A(2) in the maintenance of insulin stores but not in the initiation of insulin secretion
Journal Article
Persaud, S. J., Roderigo-Milne, H. M., Squires, P. E., Sugden, D., Wheeler-Jones, C. P. D., Marsh, P. J., …Jones, P. M. A key role for beta-cell cytosolic phospholipase A(2) in the maintenance of insulin stores but not in the initiation of insulin secretion. Diabetes, 51(1), 98-104
sPLA(2) cooperates with cPLA(2)alpha to regulate prostacyclin synthesis in human endothelial cells
Journal Article
Houliston, R. A., & Wheeler-Jones, C. P. D. sPLA(2) cooperates with cPLA(2)alpha to regulate prostacyclin synthesis in human endothelial cells. Biochemical and Biophysical Research Communications, 287(4), 881-887. https://doi.org/10.1006/bbrc.2001.5681
Agonist-specific cross talk between ERKs and p38(mapk) regulates PGI(2) synthesis in endothelium
Journal Article
Houliston, R. A., Pearson, J. D., & Wheeler-Jones, C. P. D. Agonist-specific cross talk between ERKs and p38(mapk) regulates PGI(2) synthesis in endothelium
C-type natriuretic peptide regulation of guanosine-3',5'-cyclic monophosphate production in human endothelial cells
Journal Article
Rautureau, Y., Gowers, I., Wheeler-Jones, C. P. D., & Baxter, G. F. C-type natriuretic peptide regulation of guanosine-3',5'-cyclic monophosphate production in human endothelial cells. https://doi.org/10.1111/j.1474-8673.2009.00449.x
Protease-activated receptors, cyclo-oxygenases and pro-angiogenic signalling in endothelial cells
Journal Article
Wheeler-Jones, C. P. D., Farrar, C. E., & Garonna, E. Protease-activated receptors, cyclo-oxygenases and pro-angiogenic signalling in endothelial cells. Biochemical Society Transactions, 37, 1179-1183. https://doi.org/10.1042/bst0371179
Molecular characterisation and functional interrogation of a local natriuretic peptide system in rodent pituitaries, alpha T3-1 and L beta T2 gonadotroph cells
Journal Article
Thompson, I. R., Chand, A. N., Jonas, K. C., Burrin, J. M., Steinhelper, M. E., Wheeler-Jones, C. P. D., …Fowkes, R. C. Molecular characterisation and functional interrogation of a local natriuretic peptide system in rodent pituitaries, alpha T3-1 and L beta T2 gonadotroph cells. Journal of Endocrinology, 203(2), 215-229. https://doi.org/10.1677/joe-09-0189
Expression of blood coagulation factors on monocytes after exposure to TNF-treated endothelium in a novel whole blood model of arterial flow
Journal Article
Macey, M. G., Wolf, S. I., Wheeler-Jones, C. P. D., & Lawson, C. Expression of blood coagulation factors on monocytes after exposure to TNF-treated endothelium in a novel whole blood model of arterial flow. Journal of Immunological Methods, 350(1-2), 133-141. https://doi.org/10.1016/j.jim.2009.08.007
CELECOXIB ENHANCES ENDOTHELIAL HO-1 EXPRESSION AND ACTIVITY: A NOVEL MECHANISM OF VASCULAR CYTOPROTECTION
Journal Article
Hamdulay, S. S., Wang, B. F., Haskard, D. O., Wheeler-Jones, C. P. D., & Mason, J. CELECOXIB ENHANCES ENDOTHELIAL HO-1 EXPRESSION AND ACTIVITY: A NOVEL MECHANISM OF VASCULAR CYTOPROTECTION
Suppression of nuclear factor-kappaB activity in macrophages by chylomicron remnants: modulation by the fatty acid composition of the particles
Journal Article
De Pascale, C., Graham, V., Fowkes, R. C., Wheeler-Jones, C. P. D., & Botham, K. M. Suppression of nuclear factor-kappaB activity in macrophages by chylomicron remnants: modulation by the fatty acid composition of the particles. FEBS Journal, 276(19), 5689-5702. https://doi.org/10.1111/j.1742-4658.2009.07260.x