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Thrombin-stimnlated Pyk2 phosphorylation in human endothelium is dependent on intracellular calcium and independent of protein kinase C and Src kinases
Journal Article
Keogh, R. J., Houliston, R. A., & Wheeler-Jones, C. P. D. Thrombin-stimnlated Pyk2 phosphorylation in human endothelium is dependent on intracellular calcium and independent of protein kinase C and Src kinases. Biochemical and Biophysical Research Communications, 294(5), 1001-1008. https://doi.org/10.1016/S0006-291X%2802%2900568-5

Triacylglycerol-rich lipoproteins derived from healthy donors fed different olive oils modulate cytokine secretion and cyclooxygenase-2 expression in macrophages: the potential role of oleanolic acid
Journal Article
Graham, V. S., Lawson, C., Wheeler-Jones, C. P. D., Perona, J. S., Ruiz-Gutierrez, V., & Botham, K. M. Triacylglycerol-rich lipoproteins derived from healthy donors fed different olive oils modulate cytokine secretion and cyclooxygenase-2 expression in macrophages: the potential role of oleanolic acid. European Journal of Nutrition, 51(3), 301-309. https://doi.org/10.1007/s00394-011-0215-2

PROTEASE-ACTIVATED RECEPTOR 1 AND 2 STIMULATE ENDOTHELIAL COLONY FORMING CELL VASCULOGENESIS IN A VASCULAR ENDOTHELIAL GROWTH FACTOR-AND EXTRACELLULAR SIGNAL-REGULATED KINASE-DEPENDENT MANNER
Journal Article
Pula, G., Fortunato, T. M., & Wheeler-Jones, C. P. D. PROTEASE-ACTIVATED RECEPTOR 1 AND 2 STIMULATE ENDOTHELIAL COLONY FORMING CELL VASCULOGENESIS IN A VASCULAR ENDOTHELIAL GROWTH FACTOR-AND EXTRACELLULAR SIGNAL-REGULATED KINASE-DEPENDENT MANNER. Journal of Thrombosis and Haemostasis, 11, 648-648

Heterotypic contact reveals a COX-2-mediated suppression of osteoblast differentiation by endothelial cells: A negative modulatory role for prostanoids in VEGF-mediated cell: cell communication?
Journal Article
Clarkin, C. E., Garonna, E., Pitsillides, A. A., & Wheeler-Jones, C. P. D. Heterotypic contact reveals a COX-2-mediated suppression of osteoblast differentiation by endothelial cells: A negative modulatory role for prostanoids in VEGF-mediated cell: cell communication?. Experimental Cell Research, 314(17), 3152-3161. https://doi.org/10.1016/j.yexcr.2008.07.027

in bone, angiogenesis most be initiated appropriately, but limited once remodelling or repair is complete. Our recent findings have Supported a role for prostaglandins (PG), known modulators of osteoblast (OB) and endothelial cell (EC) behaviour, in... Read More about Heterotypic contact reveals a COX-2-mediated suppression of osteoblast differentiation by endothelial cells: A negative modulatory role for prostanoids in VEGF-mediated cell: cell communication?.

Evaluation of VEGF-Mediated signaling in primary human cells reveals a paracrine action for VEGF in osteoblast-mediated crosstalk to endothelial cells
Journal Article
Clarkin, C. E., Emery, R. J., Pitsillides, A. A., & Wheeler-Jones, C. P. D. Evaluation of VEGF-Mediated signaling in primary human cells reveals a paracrine action for VEGF in osteoblast-mediated crosstalk to endothelial cells. Journal of Cellular Physiology, 214(2), 537-544. https://doi.org/10.1002/jcp.21234

Communication between endothelial and bone cells is crucial for controlling vascular supply during bone growth, remodeling, and repair but the molecular mechanisms coordinating this intercellular crosstalk remain ill-defined. We have used primary hum... Read More about Evaluation of VEGF-Mediated signaling in primary human cells reveals a paracrine action for VEGF in osteoblast-mediated crosstalk to endothelial cells.