All Outputs (2)

N-acetylcysteine (NAC) differentially affects arterial medial calcification and bone formation: the role of L-cysteine and hydrogen sulphide (2021)
Journal Article
Orriss, I., Bourne, L. E., Patel, J. J., Davies, B. K., Neven, E., Verhulst, A., D'Haese, P. C., PD Wheeler-Jones, C., & Orriss, I. R. (in press). N-acetylcysteine (NAC) differentially affects arterial medial calcification and bone formation: the role of L-cysteine and hydrogen sulphide. Journal of Cellular Physiology, https://doi.org/10.1002/jcp.30605

Arterial medial calcification (AMC) is the deposition of calcium phosphate in the arteries. AMC is widely thought to share similarities with physiological bone formation; however, emerging evidence suggests several key differences between these proce... Read More about N-acetylcysteine (NAC) differentially affects arterial medial calcification and bone formation: the role of L-cysteine and hydrogen sulphide.

Natriuretic peptide expression and function in GH3 somatolactotropes and feline somatotrope pituitary tumors (2021)
Journal Article
Mirczuk, S., Scudder, C., Read, J., Crossley, V., Regan, J., Richardson, K., Simbi, B., Mcardle, C., Church, D., Fenn, J., Kenny, P., Volk, H., Wheeler-Jones, C., Korbonits, M., Niessen, S., Mcgonnell, I., & Fowkes, R. (2021). Natriuretic peptide expression and function in GH3 somatolactotropes and feline somatotrope pituitary tumors. International Journal of Molecular Sciences, -. https://doi.org/10.3390/ijms22031076

Patients harbouring mutations in genes encoding C-type natriuretic peptide (CNP; NPPC) or its receptor guanylyl cyclase B (GC-B, NPR2) suffer from severe growth phenotypes; loss-of-function mutations cause achondroplasia, whereas gain-of-function mut... Read More about Natriuretic peptide expression and function in GH3 somatolactotropes and feline somatotrope pituitary tumors.