All Outputs (2)

Proteomic Analysis Reveals Age-related Changes in Tendon Matrix Composition, with Age- and Injury-specific Matrix Fragmentation (2014)
Journal Article
Peffers, M. J., Thorpe, C. T., Collins, J. A., Eong, R., Wei, T. K., Screen, H. R., & Clegg, P. D. (2014). Proteomic Analysis Reveals Age-related Changes in Tendon Matrix Composition, with Age- and Injury-specific Matrix Fragmentation. Journal of Biological Chemistry, 289(37), 25867-78. https://doi.org/10.1074/jbc.M114.566554

Energy storing tendons, such as the human Achilles and equine superficial digital flexor tendon (SDFT), are highly prone to injury, the incidence of which increases with aging. The cellular and molecular mechanisms that result in increased injury in... Read More about Proteomic Analysis Reveals Age-related Changes in Tendon Matrix Composition, with Age- and Injury-specific Matrix Fragmentation.

Fascicles from energy-storing tendons show an age-specific response to cyclic fatigue loading (2014)
Journal Article
Thorpe, C. T., Riley, G. P., Birch, H. L., Clegg, P. D., & Screen, H. R. C. (2014). Fascicles from energy-storing tendons show an age-specific response to cyclic fatigue loading. https://doi.org/10.1098/rsif.2013.1058

Some tendons, such as the human Achilles and equine superficial digital flexor tendon (SDFT), act as energy stores, stretching and recoiling to increase efficiency during locomotion. Our previous observations of rotation in response to applied strain... Read More about Fascicles from energy-storing tendons show an age-specific response to cyclic fatigue loading.