All Outputs (3)

Distribution of proteins within different compartments of tendon varies according to tendon type (2016)
Journal Article
Thorpe, C. T., Karunaseelan, K. J., Ng Chieng Hin, J., Riley, G. P., Birch, H. L., Clegg, P. D., & Screen, H. R. (2016). Distribution of proteins within different compartments of tendon varies according to tendon type. Journal of Anatomy, 229(3), 450-8. https://doi.org/10.1111/joa.12485

Although the predominant function of all tendons is to transfer force from muscle to bone and position the limbs, some tendons additionally function as energy stores, reducing the energetic cost of locomotion. To maximise energy storage and return, e... Read More about Distribution of proteins within different compartments of tendon varies according to tendon type.

Anatomical heterogeneity of tendon: Fascicular and interfascicular tendon compartments have distinct proteomic composition (2016)
Journal Article
Thorpe, C. T., Peffers, M. J., Simpson, D., Hallwell, E., Screen, H. R., & Clegg, P. D. (2016). Anatomical heterogeneity of tendon: Fascicular and interfascicular tendon compartments have distinct proteomic composition. https://doi.org/10.1038/srep20455

Tendon is a simple aligned fibre composite, consisting of collagen-rich fascicles surrounded by a softer interfascicular matrix (IFM). The composition and interactions between these material phases are fundamental in ensuring tissue mechanics meet fu... Read More about Anatomical heterogeneity of tendon: Fascicular and interfascicular tendon compartments have distinct proteomic composition.

Fascicles and the interfascicular matrix show adaptation for fatigue resistance in energy storing tendons (2016)
Journal Article
Thorpe, C. T., Riley, G. P., Birch, H. L., Clegg, P. D., & Screen, H. R. C. (2016). Fascicles and the interfascicular matrix show adaptation for fatigue resistance in energy storing tendons. Acta Biomaterialia, 42, 308-315. https://doi.org/10.1016/j.actbio.2016.06.012

Tendon is composed of rope-like fascicles, bound together by interfascicular matrix (IFM). Our previous work shows that the IFM is critical for tendon function, facilitating sliding between fascicles to allow tendons to stretch. This function is part... Read More about Fascicles and the interfascicular matrix show adaptation for fatigue resistance in energy storing tendons.