All Outputs (9)

Pituitary pathology and gene expression in acromegalic cats (2019)
Journal Article
Scudder, C. J., Mirczuk, S. M., Richardson, K. M., Crossley, V. J., Regan, J. T. C., Gostelow, R., …Niessen, S. J. M. (2019). Pituitary pathology and gene expression in acromegalic cats. Journal of the Endocrine Society, 3(1), 181-200. https://doi.org/10.1210/js.2018-00226

The prevalence of growth hormone secreting pituitary tumours in domestic cats (Felis catus) is ten times greater than in humans. The predominant inhibitory receptors of growth hormone-secreting pituitary tumours are somatostatin receptors (SSTRs) and... Read More about Pituitary pathology and gene expression in acromegalic cats.

Lipoma in dogs under primary veterinary care in the UK: prevalence and breed associations (2018)
Journal Article
O'Neill, D. G., Corah, C. H., Church, D. B., Brodbelt, D. C., & Rutherford, L. (2018). Lipoma in dogs under primary veterinary care in the UK: prevalence and breed associations. Canine Genetics and Epidemiology, 5(9), https://doi.org/10.1186/s40575-018-0065-9

Feline hypersomatotropism and acromegaly tumorigenesis: a potential role for the AIP gene (2017)
Journal Article
Scudder, C. J., Niessen, S. J. M., Catchpole, B., Fowkes, R. C., Church, D. B., & Forcada, Y. (2017). Feline hypersomatotropism and acromegaly tumorigenesis: a potential role for the AIP gene. Domestic Animal Endocrinology, 59, 134-139. https://doi.org/10.1016/j.domaniend.2016.11.005

Acromegaly in humans is usually sporadic, however up to 20% of familial isolated pituitary adenomas are caused by germline sequence variants of the aryl-hydrocarbon-receptor interacting protein (AIP) gene. Feline acromegaly has similarities to human... Read More about Feline hypersomatotropism and acromegaly tumorigenesis: a potential role for the AIP gene.

Dogs attending primary-care practice in England with clinical signs suggestive of Chiari-like malformation/syringomyelia (2016)
Journal Article
Sanchis-Mora, S., Pelligand, L., Thomas, C. L., Volk, H. A., Abeyesinghe, S. M., Brodbelt, D. C., …O'Neill, D. G. (2016). Dogs attending primary-care practice in England with clinical signs suggestive of Chiari-like malformation/syringomyelia. Veterinary Record, 179(17), 436. https://doi.org/10.1136/vr.103651

Chiari-like malformation/syringomyelia (CM/SM) in dogs describes a developmental disorder that can cause pain and reduced quality of life. This retrospective study aimed to report the period prevalence, clinical signs and risk factors for diagnosis o... Read More about Dogs attending primary-care practice in England with clinical signs suggestive of Chiari-like malformation/syringomyelia.

Studying Cat (Felis catus) Diabetes: Beware of the Acromegalic Imposter (2015)
Journal Article
Niessen, S. J. M., Forcada, Y., Mantis, P., Lamb, C. R., Harrington, N., Fowkes, R. C., …Church, D. B. (2015). Studying Cat (Felis catus) Diabetes: Beware of the Acromegalic Imposter. PLoS ONE, 10(5), e0127794. https://doi.org/10.1371/journal.pone.0127794

Chronic Kidney Disease in Dogs in UK Veterinary Practices: Prevalence, Risk Factors, and Survival (2013)
Journal Article
O'Neill, D. G., Elliott, J., Church, D. B., McGreevy, P. D., Thomson, P. C., & Brodbelt, D. C. (2013). Chronic Kidney Disease in Dogs in UK Veterinary Practices: Prevalence, Risk Factors, and Survival. Journal of Veterinary Internal Medicine, 27(4), 814-821. https://doi.org/10.1111/jvim.12090

Pasireotide Long-Acting Release Treatment for Diabetic Cats with Underlying Hypersomatotropism
Journal Article
Gostelow, R. S. C., Keyte, S., Forcada, Y., Fowkes, R. C., Schmid, H. A., Church, D. B., & Niessen, S. J. M. (in press). Pasireotide Long-Acting Release Treatment for Diabetic Cats with Underlying Hypersomatotropism. Journal of Veterinary Internal Medicine, 31(2), 355-364. https://doi.org/10.1111/jvim.14662

Novel diabetes mellitus treatment: mature canine insulin production by canine striated muscle through gene therapy
Journal Article
Niessen, S. J. M., Fernandez-Fuente, M., Mahmoud, A., Campbell, S. C., Aldibbiat, A., Huggins, C., …Church, D. B. Novel diabetes mellitus treatment: mature canine insulin production by canine striated muscle through gene therapy. Domestic Animal Endocrinology, 43(1), 16-25. https://doi.org/10.1016/j.domaniend.2012.01.006

Luteinizing hormone and follicle-stimulating hormone receptors and their transcribed genes (mRNA) are present in the lower urinary tract of intact male and female dogs
Journal Article
Ponglowhapan, S., Church, D. B., Scaramuzzi, R. J., & Khalid, M. Luteinizing hormone and follicle-stimulating hormone receptors and their transcribed genes (mRNA) are present in the lower urinary tract of intact male and female dogs. Theriogenology, 67(2), 353-366. https://doi.org/10.1016/j.theriogenology.2006.08.007