All Outputs (4)

A Functional Single-Nucleotide Polymorphism Upstream of the Collagen Type III Gene Is Associated with Catastrophic Fracture Risk in Thoroughbred Horses (2023)
Journal Article
Lago, E. P., Baird, A., Blott, S. C., Mcphail, R. E., Ross, A. C., Durward-Akhurst, S. A., & Guest, D. J. (2023). A Functional Single-Nucleotide Polymorphism Upstream of the Collagen Type III Gene Is Associated with Catastrophic Fracture Risk in Thoroughbred Horses. Animals, 14(1), 116. https://doi.org/10.3390/ani14010116

Fractures caused by bone overloading are a leading cause of euthanasia in Thoroughbred racehorses. The risk of fatal fracture has been shown to be influenced by both environmental and genetic factors but, to date, no specific genetic mechanisms unde... Read More about A Functional Single-Nucleotide Polymorphism Upstream of the Collagen Type III Gene Is Associated with Catastrophic Fracture Risk in Thoroughbred Horses.

Equine induced pluripotent stem cells are responsive to inflammatory cytokines before and after differentiation into musculoskeletal cell types (2023)
Journal Article
Palomino Lago, E., Jelbert, E. R., Baird, A., Lam, P. Y., & Guest, D. J. (in press). Equine induced pluripotent stem cells are responsive to inflammatory cytokines before and after differentiation into musculoskeletal cell types. In Vitro Cellular and Developmental Biology - Animal, https://doi.org/10.1007/s11626-023-00800-3

Exogenous interleukin-1 beta stimulation regulates equine tenocyte function and gene expression in three-dimensional culture which can be rescued by pharmacological inhibition of interleukin 1 receptor, but not nuclear factor kappa B, signaling (2023)
Journal Article
Beaumont, R. E., Smith, E. J., Zhou, L., Marr, N., Thorpe, C. T., & Guest, D. J. (in press). Exogenous interleukin-1 beta stimulation regulates equine tenocyte function and gene expression in three-dimensional culture which can be rescued by pharmacological inhibition of interleukin 1 receptor, but not nuclear factor kappa B, signaling. Molecular and Cellular Biochemistry, https://doi.org/10.1007/s11010-023-04779-z

Influence of Rho/ROCK inhibitor Y-27632 on proliferation of equine mesenchymal stromal cells (2023)
Journal Article
Melzer, M., Burk, J., Guest, D. J., & Dudhia, J. (in press). Influence of Rho/ROCK inhibitor Y-27632 on proliferation of equine mesenchymal stromal cells. Frontiers in Veterinary Science, 10, https://doi.org/10.3389/fvets.2023.1154987